Whole-exome sequencing
Recent articles
African genetics study NeuroDev shares initial findings
The most comprehensive study of neurodevelopmental conditions in Kenya and South Africa ever conducted shares preliminary results and lessons.
African genetics study NeuroDev shares initial findings
The most comprehensive study of neurodevelopmental conditions in Kenya and South Africa ever conducted shares preliminary results and lessons.
X-chromosome variants help explain autism’s sex bias
The rare variants are also linked to ADHD and Tourette syndrome, two other conditions that disproportionately affect boys and men.
X-chromosome variants help explain autism’s sex bias
The rare variants are also linked to ADHD and Tourette syndrome, two other conditions that disproportionately affect boys and men.
Scans of sundry variant types uncover autism-linked genes
Troves of sequencing data reveal genes tied to autism through different variant types, providing a more complete picture of the condition’s genetic roots and new clues to its heterogeneity.
Scans of sundry variant types uncover autism-linked genes
Troves of sequencing data reveal genes tied to autism through different variant types, providing a more complete picture of the condition’s genetic roots and new clues to its heterogeneity.
Macaques’ social skills tied to variation in autism-linked genes
Genetics strongly influences some aspects of the monkey’s social behavior, including tendencies to solicit grooming and sit or play alone.
Macaques’ social skills tied to variation in autism-linked genes
Genetics strongly influences some aspects of the monkey’s social behavior, including tendencies to solicit grooming and sit or play alone.
Q&A with Brenda Finucane: Building pipelines for genetic tests for autism
Most autistic people do not receive the medically recommended genetic tests for autism. Brenda Finucane and her colleagues want to change that.
Q&A with Brenda Finucane: Building pipelines for genetic tests for autism
Most autistic people do not receive the medically recommended genetic tests for autism. Brenda Finucane and her colleagues want to change that.
Autism genetics, explained
The more scientists dig into DNA, the more intricate its contribution to autism seems to be. Here, we unravel the complex genetics of autism.
Autism genetics, explained
The more scientists dig into DNA, the more intricate its contribution to autism seems to be. Here, we unravel the complex genetics of autism.
Genes tied to autism, developmental delay, schizophrenia share functions
Many genes linked to autism, schizophrenia and neurodevelopmental delay regulate gene expression and support communication between neurons.
Genes tied to autism, developmental delay, schizophrenia share functions
Many genes linked to autism, schizophrenia and neurodevelopmental delay regulate gene expression and support communication between neurons.
Largest autism genetics analysis to date uncovers more high-confidence candidates
The largest-yet study of genetic data from autistic people has identified 255 genes associated with the condition.
Largest autism genetics analysis to date uncovers more high-confidence candidates
The largest-yet study of genetic data from autistic people has identified 255 genes associated with the condition.
There are no autism-specific genes, just brain genes
There is not yet a single example of a gene that, when mutated, increases the likelihood of autism but not of other neurodevelopmental conditions, including intellectual disability.
There are no autism-specific genes, just brain genes
There is not yet a single example of a gene that, when mutated, increases the likelihood of autism but not of other neurodevelopmental conditions, including intellectual disability.
Analysis links 98 genes to neurodevelopmental conditions
Genetic sequences from nearly 53,000 people with autism, developmental delay or intellectual disability reveal strong ties to 98 genes.
Analysis links 98 genes to neurodevelopmental conditions
Genetic sequences from nearly 53,000 people with autism, developmental delay or intellectual disability reveal strong ties to 98 genes.
Explore more from The Transmitter
Mitochondrial ‘landscape’ shifts across human brain
Evolutionarily newer regions sport mitochondria with a higher capacity for energy production than older regions, according to the first detailed map of the organelles in a tissue slice, adding to mounting evidence that the brain features a metabolic gradient.
Mitochondrial ‘landscape’ shifts across human brain
Evolutionarily newer regions sport mitochondria with a higher capacity for energy production than older regions, according to the first detailed map of the organelles in a tissue slice, adding to mounting evidence that the brain features a metabolic gradient.
Expediting clinical trials for profound autism: Q&A with Matthew State
Aligning Research to Impact Autism, a new initiative funded by the Sergey Brin Family Foundation, wants to bring basic science discoveries to the clinic faster.
Expediting clinical trials for profound autism: Q&A with Matthew State
Aligning Research to Impact Autism, a new initiative funded by the Sergey Brin Family Foundation, wants to bring basic science discoveries to the clinic faster.
This paper changed my life: Shane Liddelow on two papers that upended astrocyte research
A game-changing cell culture method developed in Ben Barres’ lab completely transformed the way we study astrocytes and helped me build a career studying their reactive substates.
This paper changed my life: Shane Liddelow on two papers that upended astrocyte research
A game-changing cell culture method developed in Ben Barres’ lab completely transformed the way we study astrocytes and helped me build a career studying their reactive substates.