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Recent articles

Illustration of a binocular microscope with an X Chromosome in one eyepiece and cancer cells in the other.

The cloudy connection between fragile X and cancer

People with the autism-linked syndrome lack a protein implicated in several cancers, but it’s unclear whether — or how — they are protected from malignancies.

By Giorgia Guglielmi
28 September 2022 | 8 min read

Autism model mice develop typical social and motor behaviors after drug treatment

The drug suppresses an overactive signaling pathway implicated in tuberous sclerosis complex.

By Laura Dattaro
9 March 2022 | 5 min read
Conceptual illustration of child sleeping under blanket with multiple EEG waves overlaid on top and a window on left showing it is daytime and window on right showing nighttime.

Cracking autism’s sleep conundrum

Sleep problems may contribute to or derive from autism traits — or both. After decades of work, researchers are beginning to uncover the biological connections between the two conditions, revealing new paths to potential treatments.

By Chloe Williams
25 February 2022 | 8 min read

Molecular overlap links tuberous sclerosis, fragile X

Brain cells from the cerebellums of mice that model tuberous sclerosis show dampened levels of proteins controlled by FMRP, the protein missing in fragile X syndrome.

By Rachel Zamzow
16 August 2021 | 5 min read

Extra proteins alter microglia and behavior in mice

The overproduction of proteins in brain cells called microglia causes social impairments, cognitive deficits and repetitive behavior in male mice, a new study has found.

By Emily Anthes
29 May 2020 | 4 min read
Illustration showing the human brain with neurons made out of flower shapes and the cerebellum highlighted in gold and yellow.

Brain’s motor hub plays unsung role in social skills, cognition

Long known as the director of movement, the cerebellum may also coordinate social and cognitive abilities, including those central to autism.

By Sarah DeWeerdt
9 March 2020 | 7 min read
row of babies playing with toys that look like genome sequence

Studies of tuberous sclerosis may shed light on biology of autism

Tuberous sclerosis provides a unique opportunity to understand autism because about half of people with that single-gene condition also have autism.

By Mustafa Sahin
24 September 2019 | 5 min read

Trial results temper hopes of tumor drug for treating autism

A drug that treats tumors and epilepsy in people with tuberous sclerosis complex does not boost their intelligence or ease autism traits.

By Alla Katsnelson
29 August 2019 | 4 min read
Purkinje neurons glow red in this section.

Cerebellum’s role in autism may depend on timing

Two studies published in the past two months provide new clues to when and how the cerebellum contributes to autism.

By Nicholette Zeliadt
12 November 2018 | 5 min read
Two scientists standing in a lab.

Family ties: Sabatini brothers crack codes that may underlie autism

David and Bernardo Sabatini, brothers born just a year and a half year apart, invent their way to answering big questions about autism.

By Hannah Furfaro
30 August 2018 | 9 min read

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Rajesh Rao reflects on predictive brains, neural interfaces and the future of human intelligence

Twenty-five years ago, Rajesh Rao proposed a seminal theory of how brains could implement predictive coding for perception. His modern version zeroes in on actions.

By Paul Middlebrooks
18 December 2024 | 97 min listen

In memoriam: Yves Frégnac, influential and visionary French neuroscientist

Frégnac, who died on 18 October at the age of 73, built his career by meeting neuroscience’s complexity straight on.

By Bahar Gholipour
18 December 2024 | 9 min read
Illustration shows a solitary figure moving through a green and blue field of dots moving at different rates.

Explaining ‘the largest unexplained number in brain science’: Q&A with Markus Meister and Jieyu Zheng

The human brain takes in sensory information roughly 100 million times faster than it can respond. Neuroscientists need to explore this perceptual paradox to better understand the limits of the brain, Meister and Zheng say.

By Claudia López Lloreda
17 December 2024 | 8 min read