Treatments
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Neuroscientists need to do better at explaining basic mental health research
The knowledge gap between scientists, health-care professionals, policymakers and people with mental health conditions is growing, slowing the translation of basic science to new treatments. Like lawyers learning to present a case to the court, scientists should learn to educate nonscientists about their findings.
Neuroscientists need to do better at explaining basic mental health research
The knowledge gap between scientists, health-care professionals, policymakers and people with mental health conditions is growing, slowing the translation of basic science to new treatments. Like lawyers learning to present a case to the court, scientists should learn to educate nonscientists about their findings.
What’s next for brain-directed gene therapy after death in Neurogene trial
The incident highlights that viral vectors can trigger deadly immune responses even when delivered directly to the nervous system.
What’s next for brain-directed gene therapy after death in Neurogene trial
The incident highlights that viral vectors can trigger deadly immune responses even when delivered directly to the nervous system.
Vasopressin boosts sociability in solitary monkeys
Inhaling the hormone did not increase aggression in unsociable rhesus macaques and appears to help the animals remember faces and reciprocate friendly behaviors.
Vasopressin boosts sociability in solitary monkeys
Inhaling the hormone did not increase aggression in unsociable rhesus macaques and appears to help the animals remember faces and reciprocate friendly behaviors.
Parasite-based tool delivers MECP2 and other proteins to neurons
A method that uses a common brain parasite could help replenish the proteins deficient in Rett syndrome and other conditions.
Parasite-based tool delivers MECP2 and other proteins to neurons
A method that uses a common brain parasite could help replenish the proteins deficient in Rett syndrome and other conditions.
A genetics-first clinic for catching developmental conditions early: Q&A with Jacob Vorstman
A new clinic is assessing children who have a genetic predisposition for autism and other neurodevelopmental conditions—sometimes before traits appear.
A genetics-first clinic for catching developmental conditions early: Q&A with Jacob Vorstman
A new clinic is assessing children who have a genetic predisposition for autism and other neurodevelopmental conditions—sometimes before traits appear.
Leveraging the power of community to strengthen clinical trials for rare genetic syndromes
Families can become not only participants but champions of these research efforts.
Leveraging the power of community to strengthen clinical trials for rare genetic syndromes
Families can become not only participants but champions of these research efforts.
Tail of hippocampus may be hub for seizures in mice and people
This little-studied subregion, called the fasciola cinereum, could be a new surgical target for people with treatment-resistant epilepsy.
Tail of hippocampus may be hub for seizures in mice and people
This little-studied subregion, called the fasciola cinereum, could be a new surgical target for people with treatment-resistant epilepsy.
Pinning down ‘profound autism’ for reliable research: Q&A with Matthew Siegel
A clear and actionable definition for the term could enhance research and improve care, Matthew Siegel says.
Pinning down ‘profound autism’ for reliable research: Q&A with Matthew Siegel
A clear and actionable definition for the term could enhance research and improve care, Matthew Siegel says.
CRISPR gives autism-linked genes a boost, rescues functioning
A modified form of the gene-editing tool increases the expression of CHD8 and SCN2A, showing potential for autism therapies.
CRISPR gives autism-linked genes a boost, rescues functioning
A modified form of the gene-editing tool increases the expression of CHD8 and SCN2A, showing potential for autism therapies.
RNA drug corrects calcium signaling in chimeric model of Timothy syndrome
The drug, tested in rats that have human neurons, could enter clinical testing as early as next year, researchers say.
RNA drug corrects calcium signaling in chimeric model of Timothy syndrome
The drug, tested in rats that have human neurons, could enter clinical testing as early as next year, researchers say.
Explore more from The Transmitter
NeuroAI and the hidden complexity of agency
As we attempt to build autonomous artificial-intelligence systems, we're discovering that a capability we take for granted in animals may be much more complex than we imagined.
NeuroAI and the hidden complexity of agency
As we attempt to build autonomous artificial-intelligence systems, we're discovering that a capability we take for granted in animals may be much more complex than we imagined.
Plaque levels differ in popular Alzheimer’s mouse model depending on which parent’s variants are passed down
5XFAD model mice that inherit two disease-related genes from their fathers have double the plaques seen in those with maternal inheritance, a new study shows.
Plaque levels differ in popular Alzheimer’s mouse model depending on which parent’s variants are passed down
5XFAD model mice that inherit two disease-related genes from their fathers have double the plaques seen in those with maternal inheritance, a new study shows.
‘Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer’s,’ an excerpt
In his new book, published today, investigative journalist Charles Piller tells the story of the scientific misconduct that shook Alzheimer’s disease research to its core, and the neuroscientist who helped to expose it.
‘Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer’s,’ an excerpt
In his new book, published today, investigative journalist Charles Piller tells the story of the scientific misconduct that shook Alzheimer’s disease research to its core, and the neuroscientist who helped to expose it.