Treatments
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Finding the Rett syndrome gene and ways to fix it
Kevin Mitchell talks with Huda Zoghbi about her work identifying the MECP2 gene, its role in the brain and therapies to address its dysfunction.
Finding the Rett syndrome gene and ways to fix it
Kevin Mitchell talks with Huda Zoghbi about her work identifying the MECP2 gene, its role in the brain and therapies to address its dysfunction.
Dutch primate center awaits October animal research debate
Science is forging ahead at the Biomedical Primate Research Centre in the Netherlands, following a reversal of last year’s mandate to phase out primate studies. But researchers aren’t sure how long the reprieve will last.
Dutch primate center awaits October animal research debate
Science is forging ahead at the Biomedical Primate Research Centre in the Netherlands, following a reversal of last year’s mandate to phase out primate studies. But researchers aren’t sure how long the reprieve will last.
Study questions DSM-5’s combining of autism traits
Sensory traits and restricted and repetitive behaviors are best understood as distinct but related characteristics, the new work suggests.
Study questions DSM-5’s combining of autism traits
Sensory traits and restricted and repetitive behaviors are best understood as distinct but related characteristics, the new work suggests.
Exclusive: Brain and spinal cord institute halts research, citing funding problems
The Burke Neurological Institute, which calls itself “the only research institute in the U.S. dedicated to finding treatments to repair the brain and spinal cord,” ceased research operations on 22 May.
Exclusive: Brain and spinal cord institute halts research, citing funding problems
The Burke Neurological Institute, which calls itself “the only research institute in the U.S. dedicated to finding treatments to repair the brain and spinal cord,” ceased research operations on 22 May.
Allen Institute sets sights on treatments for five brain diseases
The Brain Health Accelerator program aims to harness single-cell transcriptomics and cell-type-specific genetic tools to develop treatments for Alzheimer’s, Huntington’s and Parkinson’s diseases, Lewy body dementia and ALS.
Allen Institute sets sights on treatments for five brain diseases
The Brain Health Accelerator program aims to harness single-cell transcriptomics and cell-type-specific genetic tools to develop treatments for Alzheimer’s, Huntington’s and Parkinson’s diseases, Lewy body dementia and ALS.
‘Overdue’ debate unfurls over neuroimaging method
After a January paper questioned the validity of an approach called lesion network mapping, its users are pressure testing their results.
‘Overdue’ debate unfurls over neuroimaging method
After a January paper questioned the validity of an approach called lesion network mapping, its users are pressure testing their results.
Nearly 400 compounds affect behaviors tied to autism-linked genes in zebrafish
Estropipate, paclitaxel and levocarnitine altered behaviors tied to SCN2A and DYRK1A variants specifically, a new open-source platform revealed.
Nearly 400 compounds affect behaviors tied to autism-linked genes in zebrafish
Estropipate, paclitaxel and levocarnitine altered behaviors tied to SCN2A and DYRK1A variants specifically, a new open-source platform revealed.
Methodological flaw may upend network mapping tool
The lesion network mapping method, used to identify disease-specific brain networks for clinical stimulation, produces a nearly identical network map for any given condition, according to a new study.
Methodological flaw may upend network mapping tool
The lesion network mapping method, used to identify disease-specific brain networks for clinical stimulation, produces a nearly identical network map for any given condition, according to a new study.
Gene replacement therapy normalizes some traits in SYNGAP1 model mice
The first published virus-based gene therapy for SYNGAP1 deletion yields benefits despite the gene’s long length and complexity.
Gene replacement therapy normalizes some traits in SYNGAP1 model mice
The first published virus-based gene therapy for SYNGAP1 deletion yields benefits despite the gene’s long length and complexity.
Nonhuman primate research to lose federal funding at major European facility
The Dutch Senate has ordered the Biomedical Primate Research Centre in the Netherlands to shift its funding away from primate experiments by 2030.
Nonhuman primate research to lose federal funding at major European facility
The Dutch Senate has ordered the Biomedical Primate Research Centre in the Netherlands to shift its funding away from primate experiments by 2030.
Explore more from The Transmitter
Remembering Barbara Finlay, ‘maverick’ of evolutionary neuroscience
Finlay, who died on 12 September, championed the idea that developmental constraints dictate how evolution sculpts brains, a concept she used to model the timing of hundreds of events and align them across mammalian species.
Remembering Barbara Finlay, ‘maverick’ of evolutionary neuroscience
Finlay, who died on 12 September, championed the idea that developmental constraints dictate how evolution sculpts brains, a concept she used to model the timing of hundreds of events and align them across mammalian species.
Crows have brains ‘in the fast lane’
The birds accurately complete decision-making tasks twice as fast as primates, although their endbrains look considerably different.
Crows have brains ‘in the fast lane’
The birds accurately complete decision-making tasks twice as fast as primates, although their endbrains look considerably different.
Prevalence of profound autism declines with new definition
The updated, more precise definition used in a CDC study includes adaptive scores.
Prevalence of profound autism declines with new definition
The updated, more precise definition used in a CDC study includes adaptive scores.