The big picture

Recent articles

Researchers ask colleagues to weigh in on important topics in the field.

Illustration of a series of shapes, with a few resembling human eyes.

The visual system’s lingering mystery: Connecting neural activity and perception

Figuring out how the brain uses information from visual neurons may require new tools. I asked 10 neuroscientists what experimental and conceptual methods they think we’re missing.

By Grace Lindsay
13 October 2025 | 24 min read
A drosophila connectome.

One year of FlyWire: How the resource is redefining Drosophila research

We asked nine neuroscientists how they are using FlyWire data in their labs, how the connectome has transformed the field and what new tools they would like to see in the future.

By Francisco J. Rivera Rosario
7 October 2025 | 17 min read
Illustration of a hand drawing lines between different points on the outline of a brain.

Beyond Newtonian causation in neuroscience: Embracing complex causality

The traditional mechanistic framework must give way to a richer understanding of how brains actually generate behavior over time.

By Luiz Pessoa
22 September 2025 | 20 min read
Hands arrange various shapes over a color background.

Emotion research has a communication conundrum

In 2025, the words we use to describe emotions matter, but their definitions are controversial. Here, I unpack the different positions in this space and the rationales behind them—and I invite 13 experts to chime in.

By Nicole Rust
5 September 2025 | 29 min read
Data streams into a transparent box.

Accepting “the bitter lesson” and embracing the brain’s complexity

To gain insight into complex neural data, we must move toward a data-driven regime, training large models on vast amounts of information. We asked nine experts on computational neuroscience and neural data analysis to weigh in.

By Eva Dyer, Blake Richards
26 March 2025 | 25 min read
Illustration of a funnel taking abstract shapes in at the top and spouting an organized flow of shapes out at the bottom.

To keep or not to keep: Neurophysiology’s data dilemma

An exponential growth in data size presents neuroscientists with a significant challenge: Should we be keeping all raw data or focusing on processed datasets? I asked experimentalists and theorists for their thoughts.

By Nima Dehghani
25 November 2024 | 24 min read
Illustration of an image of a landscape repeated over and over again, with some versions distorted and warped.

What makes memories last—dynamic ensembles or static synapses?

Teasing out how different subfields conceptualize central terms might help move this long-standing debate forward. I asked eight scientists to weigh in.

By Jason Shepherd
14 October 2024 | 30 min read
Collage of different images of brains and mechanical devices in the background with a suitcase in the foreground.

What are mechanisms? Unpacking the term is key to progress in neuroscience

Mechanism is a common and powerful concept, invoked in grant calls and publication guidelines. But scientists use it in different ways, making it difficult to clarify standards in the field. We asked nine scientists to weigh in.

By Dani S. Bassett, Lauren N. Ross
7 October 2024 | 27 min read
Illustration of a sparkly brain.

What, if anything, makes mood fundamentally different from memory?

To better understand mood disorders—and to develop more effective treatments—should we target the brain, the mind, the environment or all three?

By Nicole Rust
8 April 2024 | 21 min read
Illustration of a meteorologist pointing to an aerial view of clouds swirling over a brain-shaped land mass.

Is the brain uncontrollable, like the weather?

The brain may be chaotic. Does that mean our efforts to control it are doomed?

By Nicole Rust
18 December 2023 | 24 min read

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Explore more from The Transmitter

Two hands hold a paper airplane.

How will neuroscience training need to change in the future?

Training in computational neuroscience, data science and statistics will need to expand, say many of the scientists we surveyed. But that must be balanced with a more traditional grounding in the scientific method and critical thinking. Researchers noted that funding concerns will also affect training, especially for people from underrepresented groups.

By The Transmitter
15 November 2025 | 11 min read
Composite of headshots of neuroscientists who passed away in the past several years.

The leaders we have lost

Learn more about the lives and legacies of the neuroscientists who passed away between 2023 and 2025.

By The Transmitter
15 November 2025 | 4 min read
Stack of papers.

What are the most-cited neuroscience papers from the past 30 years?

Highly cited papers reflect the surge in artificial-intelligence research in the field and other technical advances, plus prizewinning work on analgesics, the fusiform face area and ion channels.

By The Transmitter
15 November 2025 | 11 min read

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