Systems neuroscience

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Psilocybin rewires specific mouse cortical networks in lasting ways

Neuronal activity induced by the psychedelic drug strengthens inputs from sensory brain areas and weakens cortico-cortical recurrent loops.

By Siddhant Pusdekar
5 December 2025 | 0 min watch
Illustration of a group of neurons.

This paper changed my life: Nancy Padilla-Coreano on learning the value of population coding

The 2013 Nature paper by Mattia Rigotti and his colleagues revealed how mixed selectivity neurons—cells that are not selectively tuned to a stimulus—play a key role in cognition.

By Nancy Padilla-Coreano
1 December 2025 | 5 min read
Two bouncing balls.

What are the fastest-growing areas in neuroscience?

Respondents pointed to computational neuroscience, systems neuroscience, neuroimmunology and neuroimaging, among other subfields.

By The Transmitter
15 November 2025 | 6 min read
Collage illustration of a brain, people looking at the brain, and geometric shapes.

Neuroscience needs engineers—for more reasons than you think

Adopting an engineering mindset will help the field focus its research priorities.

By Timothy O’Leary
3 November 2025 | 8 min read
Illustration of a series of floating pools of water overflowing into each other.

The missing half of the neurodynamical systems theory

Bifurcations—an underexplored concept in neuroscience—can help explain how small differences in neural circuits give rise to entirely novel functions.

By Xiao-Jing Wang
27 October 2025 | 8 min read

Explore more from The Transmitter

Home makeover helps rats better express themselves: Q&A with Raven Hickson and Peter Kind

The “Habitat”—a complex environment with space for large social groups—expands the behavioral repertoire of rodent models, Hickson and Kind say.

By Holly Barker
4 December 2025 | 0 min watch

Tatiana Engel explains how to connect high-dimensional neural circuitry with low-dimensional cognitive functions

Neuroscientists have long sought to understand the relationship between structure and function in the vast connectivity and activity patterns in the brain. Engel discusses her modeling approach to discovering the hidden patterns that connect the two.

By Paul Middlebrooks
3 December 2025 | 1 min read
A hand holds a clear rectangular prism up to a series of abstract patterns, offering a new view of them.

Beyond the algorithmic oracle: Rethinking machine learning in behavioral neuroscience

Machine learning should not be a replacement for human judgment but rather help us embrace the various assumptions and interpretations that shape behavioral research.

By Nedah Nemati, Matthew Whiteway
3 December 2025 | 7 min read

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