Systems neuroscience

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Researcher hands and mice navigate a series of connected spaces and paths.

To understand decision-making, we need to truly challenge lab animals

Complex, multidimensional tasks that unfold over time could reveal how different brain areas work together to support decisions.

By Chand Chandrasekaran
20 April 2026 | 6 min read
A fragmenting cube hovers over a person reading a book.

Error equation predicts brain’s ability to generalize

Four statistical measurements of neural network geometry capture how well brains and artificial networks use what they already know to solve new problems, a study suggests.

By Natalia Mesa
10 April 2026 | 5 min read
Digital model of a fly next to a digital model of a nematode.

‘Digital sphinx’ raises questions about connectome models

The sphinx, with a worm’s brain and a fly’s body, illustrates the potential pitfalls of using deep-learning techniques to model biological processes.

By Natalia Mesa
2 April 2026 | 5 min read

Head direction cells stably orient mice to outside world

The cells’ representations show little drift over time—unlike those of other navigation system neurons—and may provide a “rigid backbone” for more flexible sensory and cognitive responses.

By Angie Voyles Askham
25 March 2026 | 0 min watch
Research image of a mouse hippocampus.

Hippocampus builds reputation as ‘general-purpose statistical learning machine’

New cross-species findings may help settle a long-standing debate about whether the hippocampus is required for passive learning.

By Natalia Mesa
10 March 2026 | 5 min read

Explore more from The Transmitter

What Trump’s psychedelics executive order means for basic neuroscience

The order provides a potential path to remove some psychedelic drugs from the strictest regulatory category, yet it “may not be the breakthrough the basic research community has been looking for,” says neuroscientist Shawn Lockery.

By Calli McMurray
24 April 2026 | 4 min read

Switching neural code may solve ongoing face-recognition debate

Face patch cells in macaque monkeys initially respond to images of any object but rapidly transition to attend to faces exclusively, a new study finds.

By Holly Barker
23 April 2026 | 5 min read

Liset de la Prida explains how neuron subtypes may control the activity of large neural populations, from manifolds to ripples

De la Prida's work analyzing the varieties of sharp wave ripples in the hippocampus led to her discovery that specific types of neurons control the properties of neural manifolds.

By Paul Middlebrooks
22 April 2026 | 104 min listen