Systems neuroscience

Recent articles

Sign up for our weekly newsletter.

Catch up on what you missed from our recent coverage, and get breaking news alerts.

Headshots of Karl Deisseroth, Peter Hegemann and Georg Nagel.

How Nobel Prize-winning optogenetics has revolutionized neuroscience

The technique has enabled neuroscientists to target brain circuits and cells with unprecedented specificity, transforming the study of memory, interoception, brain disorders and reward, among other domains.

Illustration of two cats jumping to opposite buildings in a city.

Is confidence a second thought—or part of the first one?

In some settings, neural circuits may calculate confidence in a decision simultaneously with the choice itself. That changes the types of questions researchers should ask.

By Ariel Zylberberg
5 October 2026 | 6 min read
Research diagram of task-aligned activity rasters.

Cerebellar neurons reorient brain activity to differentiate similar behaviors

The findings provide a new perspective on how granule cells help to generalize learning across tasks.

By Holly Barker
29 September 2026 | 4 min read

Neuromechanical models deepen our understanding of animal motor control

Thanks to recent progress in physics-based simulators and robotics, it has never been easier for neuroscientists to use neuromechanical modeling to test hypotheses about animal movement.

By Auke Ijspeert
9 September 2026 | 0 min watch
Illustration of three steps to build an origami polyhedron.

Dimensionality—neuroscience’s red herring?

Placing too much emphasis on a specific interpretation of dimensionality, or treating it as an end-all quantification of some aspect of neural computation, may hinder progress in understanding the brain.

By Matthew Perich
7 September 2026 | 8 min read

Explore more from The Transmitter

Illustrated collage of a monkey profile, a gloved hand holding a vaccine syringe touching an outline of the United States with two primates sitting near it, a strand of DNA, and flags of the United States and China in the background.

U.S. national primate research centers face an uncertain future

The facilities were meant to last 100 years. Four decades shy of that mark, amid flatlined funds and mounting political pressure, their directors are trying to find a path forward.

By Calli McMurray
9 October 2026 | 12 min read
Reflections of primates in lab equipment (bottom left: Rhesus macaque, top left: Pig-tailed macaque, bottom right: Crab-eating macaque. top right: Marmoset

What if nonhuman primate research goes away?

As the U.S. government takes steps to stop using nonhuman primates in research, The Transmitter investigates what that shift could mean for neuroscience.

By The Transmitter
9 October 2026 | 2 min read
Illustration of primate hands interacting with objects of cognitive tests.

The neuroscience questions that need nonhuman primates

The Transmitter asked 17 neuroscientists what questions might remain unanswered if support for nonhuman primate research continues to decline.

By Alissa de Chassey
9 October 2026 | 10 min read