Systems neuroscience
Recent articles
How tiny tardigrades could help tackle systems neuroscience questions
The eight-legged, millimeter-long animals reveal how small nervous systems produce complex behaviors and perceptual abilities, a preprint suggests.

How tiny tardigrades could help tackle systems neuroscience questions
The eight-legged, millimeter-long animals reveal how small nervous systems produce complex behaviors and perceptual abilities, a preprint suggests.
The limits of neuroscience
Truly understanding the brain requires a set of conditions we’re unlikely to meet: that knowledge about the brain is finite, and that we have both access to that knowledge and the means to understand it.

The limits of neuroscience
Truly understanding the brain requires a set of conditions we’re unlikely to meet: that knowledge about the brain is finite, and that we have both access to that knowledge and the means to understand it.
Soft touch quells loneliness in mice
Touch modulates one of two dueling types of hypothalamic neurons that, thermostat-like, balance an animal’s drive for social interaction.

Soft touch quells loneliness in mice
Touch modulates one of two dueling types of hypothalamic neurons that, thermostat-like, balance an animal’s drive for social interaction.
Claims of necessity and sufficiency are not well suited for the study of complex systems
The earliest studies on necessary and sufficient neural populations were performed on simple invertebrate circuits. Does this logic still serve us as we tackle more sophisticated outputs?

Claims of necessity and sufficiency are not well suited for the study of complex systems
The earliest studies on necessary and sufficient neural populations were performed on simple invertebrate circuits. Does this logic still serve us as we tackle more sophisticated outputs?
Subthalamic plasticity helps mice squelch innate fear responses
When the animals learn that a perceived threat is not dangerous, long-term activity changes in a part of the subthalamus suppress their instinctive fears.

Subthalamic plasticity helps mice squelch innate fear responses
When the animals learn that a perceived threat is not dangerous, long-term activity changes in a part of the subthalamus suppress their instinctive fears.
In memoriam: Yves Frégnac, influential and visionary French neuroscientist
Frégnac, who died on 18 October at the age of 73, built his career by meeting neuroscience’s complexity straight on.

In memoriam: Yves Frégnac, influential and visionary French neuroscientist
Frégnac, who died on 18 October at the age of 73, built his career by meeting neuroscience’s complexity straight on.
What are recurrent networks doing in the brain?
The cortex is filled with excitatory local synapses, but we know little about their role in brain function. New experimental tools, along with ideas from artificial intelligence, are poised to change that.

What are recurrent networks doing in the brain?
The cortex is filled with excitatory local synapses, but we know little about their role in brain function. New experimental tools, along with ideas from artificial intelligence, are poised to change that.
Imagining the ultimate systems neuroscience paper
A growing body of papers on systems neuroscience and on giant simulations of neural circuits involves data beyond the point that anyone can reasonably understand end to end. Looking ahead, “paper-bots” could solve that problem.

Imagining the ultimate systems neuroscience paper
A growing body of papers on systems neuroscience and on giant simulations of neural circuits involves data beyond the point that anyone can reasonably understand end to end. Looking ahead, “paper-bots” could solve that problem.
How to be a multidisciplinary neuroscientist
Neuroscience subfields are often siloed. Embracing an integrative approach during training can help change that.

How to be a multidisciplinary neuroscientist
Neuroscience subfields are often siloed. Embracing an integrative approach during training can help change that.
Widely distributed brain areas sync to orchestrate decisions in rodents
Multiple brain areas synchronize their activity to help a rodent accumulate the evidence it needs to make a choice, two new studies suggest.

Widely distributed brain areas sync to orchestrate decisions in rodents
Multiple brain areas synchronize their activity to help a rodent accumulate the evidence it needs to make a choice, two new studies suggest.
Explore more from The Transmitter
Single-neuron recordings are helping to unravel complexities of human cognition
As this work begins to bear fruit, researchers “are becoming less afraid to ask very difficult questions that you can uniquely ask in people.”

Single-neuron recordings are helping to unravel complexities of human cognition
As this work begins to bear fruit, researchers “are becoming less afraid to ask very difficult questions that you can uniquely ask in people.”
The future of neuroscience research at U.S. minority-serving institutions is in danger
Cuts to federally funded programs present an existential crisis for the University of Puerto Rico’s rich neuroscience community and for research at minority-serving institutions everywhere.

The future of neuroscience research at U.S. minority-serving institutions is in danger
Cuts to federally funded programs present an existential crisis for the University of Puerto Rico’s rich neuroscience community and for research at minority-serving institutions everywhere.
Sequencing study spotlights tight web of genes tied to autism
The findings, shared in a preprint, help to illuminate how a large and heterogeneous group of genes could be involved in autism.

Sequencing study spotlights tight web of genes tied to autism
The findings, shared in a preprint, help to illuminate how a large and heterogeneous group of genes could be involved in autism.