Systems neuroscience

Recent articles

Sign up for our weekly newsletter.

Catch up on what you missed from our recent coverage, and get breaking news alerts.

Illustration of two cats jumping to opposite buildings in a city.

Is confidence a second thought—or part of the first one?

In some settings, neural circuits may calculate confidence in a decision simultaneously with the choice itself. That changes the types of questions researchers should ask.

By Ariel Zylberberg
5 October 2026 | 6 min read
Research diagram of task-aligned activity rasters.

Cerebellar neurons reorient brain activity to differentiate similar behaviors

The findings provide a new perspective on how granule cells help to generalize learning across tasks.

By Holly Barker
29 September 2026 | 4 min read

Neuromechanical models deepen our understanding of animal motor control

Thanks to recent progress in physics-based simulators and robotics, it has never been easier for neuroscientists to use neuromechanical modeling to test hypotheses about animal movement.

By Auke Ijspeert
9 September 2026 | 0 min watch
Illustration of three steps to build an origami polyhedron.

Dimensionality—neuroscience’s red herring?

Placing too much emphasis on a specific interpretation of dimensionality, or treating it as an end-all quantification of some aspect of neural computation, may hinder progress in understanding the brain.

By Matthew Perich
7 September 2026 | 8 min read
Two trajectories cross over each other showing areas of alignment and misalignment.

Mind over metrics: How can we tell if two brains (or AI models) are alike?

The ability to record from large populations of neurons has triggered the development of myriad methods for comparing them. But we’re still grappling with how to convert measures of likeness into a better mechanistic understanding.

By Alex Williams
17 August 2026 | 7 min read

Explore more from The Transmitter

Illustration of a plate with a cherry in front of a computer server.

What AI can learn from hunger

To enhance AI safety, take a lesson from biological brains; a small set of wants maintains durable control over a much larger cognitive system.

By Anthony Zador
5 October 2026 | 6 min read

New projectome captures ‘complex beast’ of serotonin system in mice

The whole-brain map—the first of its kind in a vertebrate—identifies five distinct neuron groups.

By Madeline Shaw
2 October 2026 | 0 min watch
Research image showing a grid of MRI images.

Silent, motion-resistant fMRI expands scans in behaving mice

The method, called SORDINO, captures brain images in animals while they move and interact.

By Diana Kwon
2 October 2026 | 5 min read