Synaptic vesicles
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Timothy Ryan on his pivotal switch from studying particle physics to decoding synaptic transmission
Dissuaded from pursuing theoretical physics and deterred by the “long feedback loop” in experimental physics, the National Academy of Sciences member took inspiration from “polymath” Watt Webb and “visionary” Stephen Smith—and learned to work “completely outside his comfort zone.”
Timothy Ryan on his pivotal switch from studying particle physics to decoding synaptic transmission
Dissuaded from pursuing theoretical physics and deterred by the “long feedback loop” in experimental physics, the National Academy of Sciences member took inspiration from “polymath” Watt Webb and “visionary” Stephen Smith—and learned to work “completely outside his comfort zone.”
Multi-omics study captures CNTNAP2’s far-ranging effects
The in-depth approach shows mutations in the autism-linked gene disrupt neuronal growth and communication, as well as mitochondrial gene expression.
Multi-omics study captures CNTNAP2’s far-ranging effects
The in-depth approach shows mutations in the autism-linked gene disrupt neuronal growth and communication, as well as mitochondrial gene expression.
How microscopic ‘condensates’ in cells might contribute to autism
A controversial idea about how cells compartmentalize their contents into droplets — like beads of oil in water — could be key to understanding autism, says Julie Forman-Kay.
How microscopic ‘condensates’ in cells might contribute to autism
A controversial idea about how cells compartmentalize their contents into droplets — like beads of oil in water — could be key to understanding autism, says Julie Forman-Kay.
New method exposes structures inside ‘rainbow’ of brain cells
Molecules from alpacas may enable scientists to identify cell types in the brain while also revealing their interior structures.
New method exposes structures inside ‘rainbow’ of brain cells
Molecules from alpacas may enable scientists to identify cell types in the brain while also revealing their interior structures.
Dividing autism; novel messengers; million-dollar mark and more
A researcher proposes splitting autism into subtypes, mitochondria make neurotransmitters, and highly successful grantees may face a funding cap.
Dividing autism; novel messengers; million-dollar mark and more
A researcher proposes splitting autism into subtypes, mitochondria make neurotransmitters, and highly successful grantees may face a funding cap.
New tool spotlights neuron junctions in living human brains
A new imaging technique allows researchers to illuminate the junctions between neurons in a living person’s brain.
New tool spotlights neuron junctions in living human brains
A new imaging technique allows researchers to illuminate the junctions between neurons in a living person’s brain.
Rainbow of dyes maps neurons’ tangled paths in brain
A new method that lets researchers trace the paths of many neurons at once may reveal how neurons go astray in autism.
Rainbow of dyes maps neurons’ tangled paths in brain
A new method that lets researchers trace the paths of many neurons at once may reveal how neurons go astray in autism.
Suite of methods yields complex model of neuronal junctions
Researchers debuted a three-dimensional model of an average synapse, the point of connection between neurons, in the 30 May issue of Science.
Suite of methods yields complex model of neuronal junctions
Researchers debuted a three-dimensional model of an average synapse, the point of connection between neurons, in the 30 May issue of Science.
Molecular mechanisms: Autism gene establishes brain links
The autism-linked protein MET is expressed at the junctions between neurons during early brain development in mice, suggesting that it helps establish the connections, according to a study published 21 June in The Journal of Comparative Neurology.
Molecular mechanisms: Autism gene establishes brain links
The autism-linked protein MET is expressed at the junctions between neurons during early brain development in mice, suggesting that it helps establish the connections, according to a study published 21 June in The Journal of Comparative Neurology.
Researchers watch as proteins travel to neuronal junctions
Using high-resolution microscopy, researchers can watch as signaling complexes assemble at neuronal junctions in zebrafish embryos, according to a study published 17 April in Cell Reports.
Researchers watch as proteins travel to neuronal junctions
Using high-resolution microscopy, researchers can watch as signaling complexes assemble at neuronal junctions in zebrafish embryos, according to a study published 17 April in Cell Reports.
Explore more from The Transmitter
Autism program chief among National Institutes of Health layoffs
The termination is one of more than 1,000 employee cuts at the U.S. agency this week.
Autism program chief among National Institutes of Health layoffs
The termination is one of more than 1,000 employee cuts at the U.S. agency this week.
This paper changed my Life: Bill Newsome reflects on a quadrilogy of classic visual perception studies
The 1970s papers from Goldberg and Wurtz made ambitious mechanistic studies of higher brain functions seem feasible.
This paper changed my Life: Bill Newsome reflects on a quadrilogy of classic visual perception studies
The 1970s papers from Goldberg and Wurtz made ambitious mechanistic studies of higher brain functions seem feasible.
Science must step away from nationally managed infrastructure
Scientific data and independence are at risk. We need to work with community-driven services and university libraries to create new multi-country organizations that are resilient to political interference.
Science must step away from nationally managed infrastructure
Scientific data and independence are at risk. We need to work with community-driven services and university libraries to create new multi-country organizations that are resilient to political interference.