Synaptic plasticity
Recent articles
Cracking the code of the extracellular matrix
Despite evidence for a role in plasticity and other crucial functions, many neuroscientists still view these proteins as “brain goop.” The field needs technical advances and a shift in scientific thinking to move beyond this outdated perspective.
Cracking the code of the extracellular matrix
Despite evidence for a role in plasticity and other crucial functions, many neuroscientists still view these proteins as “brain goop.” The field needs technical advances and a shift in scientific thinking to move beyond this outdated perspective.
Synaptic changes shape winning mice into bullies
When a mouse repeatedly defeats its opponents, brain circuits that underlie aggressive behaviors develop more stable connections, helping to ensure continual triumph, a new study shows.
Synaptic changes shape winning mice into bullies
When a mouse repeatedly defeats its opponents, brain circuits that underlie aggressive behaviors develop more stable connections, helping to ensure continual triumph, a new study shows.
What makes memories last—dynamic ensembles or static synapses?
Teasing out how different subfields conceptualize central terms might help move this long-standing debate forward. I asked eight scientists to weigh in.
What makes memories last—dynamic ensembles or static synapses?
Teasing out how different subfields conceptualize central terms might help move this long-standing debate forward. I asked eight scientists to weigh in.
This paper changed my life: ‘Response of hippocampal synapses to natural stimulation patterns,’ by Dobrunz and Stevens
The work demonstrated how to effectively combine controlled in-vitro experiments and the messiness of natural brain patterns.
This paper changed my life: ‘Response of hippocampal synapses to natural stimulation patterns,’ by Dobrunz and Stevens
The work demonstrated how to effectively combine controlled in-vitro experiments and the messiness of natural brain patterns.
‘Star’ neuroscientist faked data in paper and grant applications, U.S. government finds
The faked data, which was part of research on the genetic mechanisms of synaptic plasticity, was used to obtain more than $1.4 million in federal funding.
‘Star’ neuroscientist faked data in paper and grant applications, U.S. government finds
The faked data, which was part of research on the genetic mechanisms of synaptic plasticity, was used to obtain more than $1.4 million in federal funding.
Neurons making memories shush their neighbors
When neurons strengthen their synapses, they “infect” surrounding cells with a virus-like protein to weaken those cells’ excitatory connections, according to a new preprint.
Neurons making memories shush their neighbors
When neurons strengthen their synapses, they “infect” surrounding cells with a virus-like protein to weaken those cells’ excitatory connections, according to a new preprint.
Synaptic protein’s shape-shifting skills propel plasticity
SYNGAP supports learning without tapping its eponymous “GAP” enzymatic activity, according to a new study.
Synaptic protein’s shape-shifting skills propel plasticity
SYNGAP supports learning without tapping its eponymous “GAP” enzymatic activity, according to a new study.
Mutation in top autism-linked gene may alter eye reflex
The discovery could help clinicians diagnose children who carry mutations in the gene, called SCN2A, and gauge their responses to potential therapies.
Mutation in top autism-linked gene may alter eye reflex
The discovery could help clinicians diagnose children who carry mutations in the gene, called SCN2A, and gauge their responses to potential therapies.
Top autism-linked genes join forces to shape synaptic plasticity
The protein products of ANK2 and SCN2A interact to regulate dendritic excitability.
Top autism-linked genes join forces to shape synaptic plasticity
The protein products of ANK2 and SCN2A interact to regulate dendritic excitability.
Immune-activation model mice escape infantile amnesia, retain early memories
Male pups born to mothers treated with immune-stimulating molecules show autism-like behaviors and, unlike wildtype animals, do not lose memories formed during early life.
Immune-activation model mice escape infantile amnesia, retain early memories
Male pups born to mothers treated with immune-stimulating molecules show autism-like behaviors and, unlike wildtype animals, do not lose memories formed during early life.
Explore more from The Transmitter
Revisiting sex and gender in the brain
To conduct scientifically accurate and socially responsible research, it is useful to think of “sex” as a complex, multifactorial and context-dependent variable.
Revisiting sex and gender in the brain
To conduct scientifically accurate and socially responsible research, it is useful to think of “sex” as a complex, multifactorial and context-dependent variable.
Cortical myelination; early vocabulary; EEG in tuberous sclerosis
Here is a roundup of autism-related news and research spotted around the web for the week of 27 January.
Cortical myelination; early vocabulary; EEG in tuberous sclerosis
Here is a roundup of autism-related news and research spotted around the web for the week of 27 January.
The brain holds no exclusive rights on how to create intelligence
Many of the recent developments underlying the explosive success of artificial intelligence have diverged from using neuroscience as a source of inspiration—and the trend is likely to continue.
The brain holds no exclusive rights on how to create intelligence
Many of the recent developments underlying the explosive success of artificial intelligence have diverged from using neuroscience as a source of inspiration—and the trend is likely to continue.