Stem cells
Recent articles
Microglia nurture young interneurons
The immune cells secrete a growth factor that “sets the supply of GABAergic interneurons in the developing brain.”

Microglia nurture young interneurons
The immune cells secrete a growth factor that “sets the supply of GABAergic interneurons in the developing brain.”
Why hype for autism stem cell therapies continues despite dead ends
After numerous tests, there is still no evidence that these experimental treatments help, so now is not the time to expand access to them.

Why hype for autism stem cell therapies continues despite dead ends
After numerous tests, there is still no evidence that these experimental treatments help, so now is not the time to expand access to them.
Cell ‘antennae’ link autism, congenital heart disease
Variants in genes tied to both conditions derail the formation of cilia, the tiny hair-like structure found on almost every cell in the body, a new study finds.
Cell ‘antennae’ link autism, congenital heart disease
Variants in genes tied to both conditions derail the formation of cilia, the tiny hair-like structure found on almost every cell in the body, a new study finds.
In vivo veritas: Xenotransplantation can help us study the development and function of human neurons in a living brain
Transplanted cells offer insight into human-specific properties, such as a lengthy cortical development and sensitivity to neurodevelopmental and neurodegenerative disease.

In vivo veritas: Xenotransplantation can help us study the development and function of human neurons in a living brain
Transplanted cells offer insight into human-specific properties, such as a lengthy cortical development and sensitivity to neurodevelopmental and neurodegenerative disease.
Organoids and assembloids offer a new window into human brain
These sophisticated 3D cultures reveal previously inaccessible stages of human brain development and enable the systematic study of disease genes.

Organoids and assembloids offer a new window into human brain
These sophisticated 3D cultures reveal previously inaccessible stages of human brain development and enable the systematic study of disease genes.
Impaired molecular ‘chaperone’ accompanies multiple brain changes, conditions
Rare genetic variants in a protein-folding complex contribute to a spectrum of phenotypes that encompass brain malformations, intellectual disability, autism and seizures, according to a new “hallmark” study.

Impaired molecular ‘chaperone’ accompanies multiple brain changes, conditions
Rare genetic variants in a protein-folding complex contribute to a spectrum of phenotypes that encompass brain malformations, intellectual disability, autism and seizures, according to a new “hallmark” study.
Brain organoid size matches intensity of social problems in autistic people
Overgrown organoids could point to mechanisms underlying profound autism.

Brain organoid size matches intensity of social problems in autistic people
Overgrown organoids could point to mechanisms underlying profound autism.
Autism subgroups converge on cell growth pathway
Faulty mTOR signaling, implicated in syndromic forms of autism, also hinders cells grown from people with idiopathic autism or autism-linked deletions on chromosome 16.

Autism subgroups converge on cell growth pathway
Faulty mTOR signaling, implicated in syndromic forms of autism, also hinders cells grown from people with idiopathic autism or autism-linked deletions on chromosome 16.
Building a brain: How does it generate its exquisite diversity of cells?
High-throughput technologies have revealed new insights into how the brain develops. But a truly comprehensive map of neurodevelopment requires further advances.

Building a brain: How does it generate its exquisite diversity of cells?
High-throughput technologies have revealed new insights into how the brain develops. But a truly comprehensive map of neurodevelopment requires further advances.
Raising the bar for stem cell research: Q&A with Jack Mosher
New quality benchmarks for basic research involving stem cells promise to improve rigor and reproducibility, says Mosher, who helped develop the standards.

Raising the bar for stem cell research: Q&A with Jack Mosher
New quality benchmarks for basic research involving stem cells promise to improve rigor and reproducibility, says Mosher, who helped develop the standards.
Explore more from The Transmitter
Autism and anxiety insights; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 15 September.

Autism and anxiety insights; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 15 September.
First nerve-net connectome shows how evolutionarily ancient nervous system coordinates movement
The map of a comb jelly’s aboral nerve net, which helps the animal orient and position itself within the water column, reveals a unique system for sensing the world and coordinating movement.
First nerve-net connectome shows how evolutionarily ancient nervous system coordinates movement
The map of a comb jelly’s aboral nerve net, which helps the animal orient and position itself within the water column, reveals a unique system for sensing the world and coordinating movement.
Paper by memory institute director garners expression of concern over image integrity
The notice, posted last week in Nature, follows a recent string of corrections to at least three other articles by Li-Huei Tsai’s lab.

Paper by memory institute director garners expression of concern over image integrity
The notice, posted last week in Nature, follows a recent string of corrections to at least three other articles by Li-Huei Tsai’s lab.