Spotlight on mouse models of autism
Spectrum Stories: Talking about autism mouse models
Scientists discuss the problems with using mice to study autism, and explain how the field might move forward.
![Spectrum stories podcast logo.](https://www.thetransmitter.org/wp-content/uploads/2018/08/Podcast-art-844.jpg)
Spectrum Stories: Talking about autism mouse models
Scientists discuss the problems with using mice to study autism, and explain how the field might move forward.
Inside Scoop From the Autism Anchors: The role of mouse models in autism
Our autism anchors, Raphael Bernier and James Mancini, explain how mouse models can help scientists understand the causes of autism and evaluate potential treatments for the condition.
![](https://www.thetransmitter.org/wp-content/uploads/2018/03/blogcast844.jpg)
Inside Scoop From the Autism Anchors: The role of mouse models in autism
Our autism anchors, Raphael Bernier and James Mancini, explain how mouse models can help scientists understand the causes of autism and evaluate potential treatments for the condition.
‘Outmoded’ mouse models of autism may still yield new advances
Many researchers question the value of three early mouse models of autism, but the models have their staunch supporters.
![illustration of mouse on sale in a city](https://www.thetransmitter.org/wp-content/uploads/2018/03/Spectrum_SpecialReport_Mice_PasseModels_FINAL_REVISED.jpg)
‘Outmoded’ mouse models of autism may still yield new advances
Many researchers question the value of three early mouse models of autism, but the models have their staunch supporters.
‘Outdated’ mouse model exposes key disruptions in autism brain
A mouse model based on exposure to an epilepsy drug offers a useful window into the brain circuits altered in autism.
![](https://www.thetransmitter.org/wp-content/uploads/2018/03/Spectrum_SpecialReport_Mice_Valporate_FINAL.jpg)
‘Outdated’ mouse model exposes key disruptions in autism brain
A mouse model based on exposure to an epilepsy drug offers a useful window into the brain circuits altered in autism.
‘Syntax’ of mouse behavior may speak volumes about autism
An algorithm that decodes and quantifies mouse body language could reveal the brain circuits underlying certain autism features.
‘Syntax’ of mouse behavior may speak volumes about autism
An algorithm that decodes and quantifies mouse body language could reveal the brain circuits underlying certain autism features.
Why studying autism in mice may be doomed to fail
After more than a decade of effort, scientists are questioning whether mouse models of autism can ever capture the social deficits seen in people with the condition.
![Mouse in a lab or maze hops around sniffing here and there](https://www.thetransmitter.org/wp-content/uploads/2018/03/spectrum_mice_lab_04-copy.gif)
Why studying autism in mice may be doomed to fail
After more than a decade of effort, scientists are questioning whether mouse models of autism can ever capture the social deficits seen in people with the condition.
Why we need a mouse version of a diagnostic test for autism
Researchers have developed behavioral measures that can accurately diagnose autism in people; these lessons can and should be applied to mice.
![scientist looks through binoculars showing a boy on one side, and a mouse on the other.](https://www.thetransmitter.org/wp-content/uploads/2018/03/Spectrum_SpecialReport_Mice_ADOS_Roughs_FINAL.jpg)
Why we need a mouse version of a diagnostic test for autism
Researchers have developed behavioral measures that can accurately diagnose autism in people; these lessons can and should be applied to mice.
How variability among mouse strains can aid autism research
Researchers can convert the distinct genetic backgrounds of lab mice from a problem to an advantage, exploiting the differences to advance our understanding of autism.
![](https://www.thetransmitter.org/wp-content/uploads/2018/03/Spectrum_SpecialReport_Mice_Bolivar_FINAL.jpg)
How variability among mouse strains can aid autism research
Researchers can convert the distinct genetic backgrounds of lab mice from a problem to an advantage, exploiting the differences to advance our understanding of autism.
What to watch for when analyzing mouse behavior
Many tests for unusual behavior in mice are prone to operator error. Here’s how to avoid common traps.
![Two mice in a waiting room.](https://www.thetransmitter.org/wp-content/uploads/2018/03/mouse-behavior-844.jpg)
What to watch for when analyzing mouse behavior
Many tests for unusual behavior in mice are prone to operator error. Here’s how to avoid common traps.
How to improve mouse models’ usefulness for understanding autism
Integrating human-specific genetic elements into mice may provide a permissive, ‘humanized’ environment for studying autism.
![](https://www.thetransmitter.org/wp-content/uploads/2018/03/Spectrum_SpecialReport_Mice_Noonan_FINAL.jpg)
How to improve mouse models’ usefulness for understanding autism
Integrating human-specific genetic elements into mice may provide a permissive, ‘humanized’ environment for studying autism.
Explore more from The Transmitter
Future of BRAIN Initiative funding remains unclear
As the U.S. Congress begins to discuss federal science funding for 2025, any plans to compensate for this year’s cuts to the neuroscience program face an uphill battle.
![Image of a crumpled dollar bill whose edges suggest a line graph trending downward.](https://www.thetransmitter.org/wp-content/uploads/2024/07/Funding-1200-1024x692.webp)
Future of BRAIN Initiative funding remains unclear
As the U.S. Congress begins to discuss federal science funding for 2025, any plans to compensate for this year’s cuts to the neuroscience program face an uphill battle.
Computational and systems neuroscience needs development
Embracing recent advances in developmental biology can drive a new wave of innovation.
![Illustration of a fly with its life cycle represented on its left and a technological background on its right.](https://www.thetransmitter.org/wp-content/uploads/2024/07/Lede-Scott-1200-1024x692.webp)
Computational and systems neuroscience needs development
Embracing recent advances in developmental biology can drive a new wave of innovation.
FOXP1 gene; dose effect of neurodevelopmental conditions; transcriptomics in mouse model of autism
Here is a roundup of autism-related news and research spotted around the web for the week of 1 July.
![Research image showing the number of unique SHANK3 transcripts in mice.](https://www.thetransmitter.org/wp-content/uploads/2024/06/Fig6A-Transcriptome-1200-1024x692.webp)
FOXP1 gene; dose effect of neurodevelopmental conditions; transcriptomics in mouse model of autism
Here is a roundup of autism-related news and research spotted around the web for the week of 1 July.