Many mouths making conversation, with speech bubbles in red and blue.
Illustration by Laurène Boglio

‘wildDISCO’ whole-mouse mapping; high-resolution imaging of living brain tissue

A new technique to map the entire body of a mouse and a high-resolution 4D imaging method for living brain tissue samples piqued researchers’ interest on social media this week — that and more in this issue of Community Newsletter.

Ali Ertürk of Ludwig-Maximilians-Universität München detailed his team’s study, “Whole-body cellular mapping in mouse using standard IgG antibodies,” published in Nature Biotechnology 10 July.

John-Paul Fuller-Jackson of the University of Melbourne and Kateryna Shkarina of the Institute of Innate Immunity were among the many who responded to Ertürk.

The Allen Institute shared a link to its new resource, the Allen Brain Cell Atlas.

 

Post by @alleninstitute
View on Threads

 

Eric Minikel of the Broad Institute explained his team’s preprint, “Refining the impact of genetic evidence on clinical success,” posted on medRxiv 29 June.

Philipp Velicky of the Medical University of Vienna described his team’s study, “Dense 4D nanoscale reconstruction of living brain tissue,” published in Nature Methods 10 July.

Reto Fiolka of the University of Texas Southwestern asked a question, to which Velicky replied.

Jakob Troidl of Harvard University responded to Velicky.

Mustafa Sahin of Harvard University posted a link to his team’s article, “Updated consensus guidelines on the management of Phelan–McDermid syndrome,” published in the American Journal of Medical Genetics 1 July.

Shani Stern of the University of Haifa linked to her team’s study, “Early maturation and hyperexcitability is a shared phenotype of cortical neurons derived from different ASD-associated mutations,” published in Translational Psychiatry 6 July.

Peter Bandettini of the National Institute of Mental Health announced the relaunch of the open-access journal Aperture Neuro.

Meng-Chuan Lai of the University of Toronto posted a link to his team’s study, “Exploring camouflaging by the Chinese version Camouflaging Autistic Traits Questionnaire in Taiwanese autistic and non-autistic adolescents: An initial development,” published in Autism 10 July.

Tyler Perfitt shared a link to his team’s study, “Clustering of CaV1.3 L-type calcium channels by Shank3,” published in Journal of Neurochemistry 30 June.

Santhosh Girirajan of Pennsylvania State University commented on “Partner selection may amplify rare variants in children,” published in Spectrum 6 July.

That’s it for this week’s Community Newsletter! If you have any suggestions for interesting social posts you saw in the autism research sphere, feel free to send an email to [email protected].

Follow us on Facebook, Twitter, Instagram and LinkedIn. We are also now on Threads!

Sign up for the weekly Spectrum newsletter.

Stay current with the latest advancements in autism research.