Development patterns: Children with agenesis of the corpus callosum, one of the most common congenital brain malformations, show developmental delays that differ from children with a family history of autism and from those with fragile X or Down syndromes, according to a recent study. They tend to have delays in communication, motor and daily living skills compared with neurotypical children at 6, 12 and 18 months of age, respectively, but similar social skills. Compared with children who have an elevated likelihood of autism, those with agenesis of the corpus callosum generally show stronger social skills, weaker motor skills and equivalent communication skills. Children with this brain malformation also tend to have stronger skills across domains than children with a genetic syndrome. Pediatrics
More autism research we spotted:
- “Self-regulating gene therapy ameliorates phenotypes and overcomes gene dosage sensitivity in a mouse model of Rett syndrome” Science Translational Medicine
- “Random forest and Shapley Additive exPlanations predict oxytocin targeted effects on brain functional networks involved in salience and sensorimotor processing, in a randomized clinical trial in autism” Neuropsychopharmacology
See also: “Intranasal oxytocin ineffective for autism in large trial”
