Spectrum

Recent articles

Spectrum is the go-to destination for the latest news and analysis about autism research and a springboard for scientists and clinicians to forge collaborations that deepen our understanding of autism.

Action potentials

Image
Upcoming event
FEBRUARY
11
2025
ASSISI
Subcortical sensory circuits: From perception to behavior
11-14 FEBRUARY 2025
Learn more
Quote

It’s a new framework to understand how microexons perform their activities. — XAVIER SALVATELLA

Read more
WHAT WE ARE READING
“Autism Spectrum Disorder Across the Lifespan”
By MAIRA TAFOLLA et al. IN ANNUAL REVIEWS IN CLINICAL PSYCHOLOGY
READ MORE
Decorative background of a grid of pale yellow envelopes.
Sign up for the weekly Spectrum newsletter.
Stay current with the latest advancements in autism research.
an illustration of scientists parachuting
Spectrum

The perils of parachute research

Scientists who study autism in lower-income countries are working to end practices that exploit or ignore collaborators and communities on the ground.

By Linda Nordling
6 June 2024 | 11 min read
Research video of a zebrafish larva (zoomed in on the gut) being given glucose.
Spectrum

On the periphery: Thinking ‘outside the brain’ offers new ideas about autism

Neuronal alterations outside the brain may help to explain a host of the condition’s characteristic traits, including sensory changes, gut problems and motor differences.

By Sarah DeWeerdt
13 April 2023 | 20 min read
See all Features See all Features - opens a new tab
Research image of different cell types in the neocortex.

New human brain atlas charts gene activity and chromosome accessibility, from embryo to adolescence

The resource profiles millions of single cells across the developing cortex, revealing when, where and how certain cell types emerge and illuminating possible origins of autism and other conditions.

By Saima Sidik
30 January 2025 | 5 min read
Research image of regional structural differences in the brains of neurodiverse people.

Cortical myelination; early vocabulary; EEG in tuberous sclerosis

Here is a roundup of autism-related news and research spotted around the web for the week of 27 January.

By Jill Adams
28 January 2025 | 2 min read
Research image of cells lacking microexon 4.

Protein aggregates gum up ‘master regulator’ of autism-linked genes

The regulator, CPEB4, typically controls protein production for hundreds of autism-linked genes, but an alternative version of it found in autistic people forms irreversible clumps and malfunctions.

By Giorgia Guglielmi
23 January 2025 | 4 min read
Research image of brain organoids with astroglia formation represented in green.

Personalized medicine; astroglia organoids; fast track for fragile X drug

Here is a roundup of autism-related news and research spotted around the web for the week of 20 January.

By Jill Adams
21 January 2025 | 2 min read
Research image highlighting different brain regions.

X marks the spot in search for autism variants

Genetic variants on the X chromosome, including those in the gene DDX53, contribute to autism’s gender imbalance, two new studies suggest.

By Holly Barker
16 January 2025 | 6 min read

Explore more from The Transmitter

‘Digital humans’ in a virtual world

By combining large language models with modular cognitive control architecture, Robert Yang and his collaborators have built agents that are capable of grounded reasoning at a linguistic level. Striking collective behaviors have emerged.

By Kevin Mitchell
10 February 2025 | 4 min read
Research image of brain glucose levels in mice.

Food for thought: Neuronal fuel source more flexible than previously recognized

The cells primarily rely on glucose—rather than lactate from astrocytes—to generate energy, according to recent findings in mice.

By Giorgia Guglielmi
7 February 2025 | 6 min read
Abstract illustration of overlapping lines.

Claims of necessity and sufficiency are not well suited for the study of complex systems

The earliest studies on necessary and sufficient neural populations were performed on simple invertebrate circuits. Does this logic still serve us as we tackle more sophisticated outputs?

By Grace Lindsay
7 February 2025 | 6 min read