Special Report: Lessons from other fields
The link between epilepsy and autism, explained
Autism and epileptic seizures often go hand in hand. What explains the overlap, and what does it reveal about autism’s origins?
![a human brain model made of springs is shaking on its spring base](https://www.thetransmitter.org/wp-content/uploads/2019/10/20190921Epilepsy844.jpg)
The link between epilepsy and autism, explained
Autism and epileptic seizures often go hand in hand. What explains the overlap, and what does it reveal about autism’s origins?
Rett syndrome’s link to autism, explained
Studies of Rett syndrome hint at genes, cells and brain circuits that may be involved in autism — and may pave the way to treatments for both conditions.
![linked hands in a pattern intertwined with DNA showing some broken parts, symbolizing mutations](https://www.thetransmitter.org/wp-content/uploads/2019/10/20190921-Rett844.jpg)
Rett syndrome’s link to autism, explained
Studies of Rett syndrome hint at genes, cells and brain circuits that may be involved in autism — and may pave the way to treatments for both conditions.
What two rare ‘social’ syndromes reveal about autism
Studying Smith-Magenis and Potocki-Lupski syndromes — two single-gene conditions in which people have trouble reading social cues — may boost our understanding of autism.
![Mouse shows friendliness to all mice, friends or strangers](https://www.thetransmitter.org/wp-content/uploads/2019/10/Walz844.jpg)
What two rare ‘social’ syndromes reveal about autism
Studying Smith-Magenis and Potocki-Lupski syndromes — two single-gene conditions in which people have trouble reading social cues — may boost our understanding of autism.
What Ehlers-Danlos syndrome can teach us about autism
Not much is known about the connection between autism and Ehlers-Danlos syndrome, a condition that affects collagen. But preliminary work provides tantalizing clues.
![](https://www.thetransmitter.org/wp-content/uploads/2019/10/EhlersDanlos-Casanova844.jpg)
What Ehlers-Danlos syndrome can teach us about autism
Not much is known about the connection between autism and Ehlers-Danlos syndrome, a condition that affects collagen. But preliminary work provides tantalizing clues.
Angelman syndrome’s silent gene points way forward for autism therapies
Advances in research and help from families have brought scientists to the brink of an effective therapy for Angelman syndrome.
![](https://www.thetransmitter.org/wp-content/uploads/2019/10/20190921-Angelman1120.jpg)
Angelman syndrome’s silent gene points way forward for autism therapies
Advances in research and help from families have brought scientists to the brink of an effective therapy for Angelman syndrome.
Single molecule tracks with mutation’s path to autism, cancer
A molecule made by mitochondria, the energy factories of cells, might help doctors forecast the impact of mutations in a top autism gene.
![](https://www.thetransmitter.org/wp-content/uploads/2019/10/PTEN844.jpg)
Single molecule tracks with mutation’s path to autism, cancer
A molecule made by mitochondria, the energy factories of cells, might help doctors forecast the impact of mutations in a top autism gene.
Getting at the heart of autism
Cardiac activity could reveal autism's physiology and confirm a hunch many clinicians share: that people with autism experience great stress.
![red beating heart, in see-through person](https://www.thetransmitter.org/wp-content/uploads/2019/10/20191009Autonomic844.jpg)
Getting at the heart of autism
Cardiac activity could reveal autism's physiology and confirm a hunch many clinicians share: that people with autism experience great stress.
Studies of tuberous sclerosis may shed light on biology of autism
Tuberous sclerosis provides a unique opportunity to understand autism because about half of people with that single-gene condition also have autism.
![row of babies playing with toys that look like genome sequence](https://www.thetransmitter.org/wp-content/uploads/2019/09/20190921-TSC-Sahin-844.jpg)
Studies of tuberous sclerosis may shed light on biology of autism
Tuberous sclerosis provides a unique opportunity to understand autism because about half of people with that single-gene condition also have autism.
Can preventing seizures alter the course of autism?
Experimental surgeries to prevent seizures may help scientists understand the link between autism and epilepsy.
![medical personnel in operating theater during brain surgery](https://www.thetransmitter.org/wp-content/uploads/2019/09/20190918-844.jpg)
Can preventing seizures alter the course of autism?
Experimental surgeries to prevent seizures may help scientists understand the link between autism and epilepsy.
The deep emotional ties between depression and autism
Autistic people are four times as likely to experience depression over the course of their lives as their neurotypical peers. Yet researchers know little about why, or how best to help.
![Boy on bed is weighed down by pressures and troubles](https://www.thetransmitter.org/wp-content/uploads/2019/07/20190731-Depression844.jpg)
The deep emotional ties between depression and autism
Autistic people are four times as likely to experience depression over the course of their lives as their neurotypical peers. Yet researchers know little about why, or how best to help.
Explore more from The Transmitter
Temperature tunes circadian timing in some desert mammals
Light has hogged all the attention in chronobiology research—but now, in camel, goat and mole rat experiments, temperature takes the lead.
![A man walks a dromedary camel down a hallway.](https://www.thetransmitter.org/wp-content/uploads/2024/06/camel-walking-1200-1024x692.webp)
Temperature tunes circadian timing in some desert mammals
Light has hogged all the attention in chronobiology research—but now, in camel, goat and mole rat experiments, temperature takes the lead.
Synaptic anomalies in autistic people support imbalance hypothesis
Increased excitatory and decreased inhibitory synapses in the prefrontal cortex of autistic people suggest broader impacts on brain function and connectivity.
![Research image of excitatory synapses in the prefrontal cortex.](https://www.thetransmitter.org/wp-content/uploads/2024/06/Fig2BD3BD-1200-1024x692.webp)
Synaptic anomalies in autistic people support imbalance hypothesis
Increased excitatory and decreased inhibitory synapses in the prefrontal cortex of autistic people suggest broader impacts on brain function and connectivity.
Opioid receptors may guide formation of gut nervous system in zebrafish
Fish lacking functional copies of the receptors have fewer enteric neurons than usual, but the findings await further validation.
![Research image of enteric neurons in zebrafish.](https://www.thetransmitter.org/wp-content/uploads/2024/06/Fig2D-fish-1200-1024x692.webp)
Opioid receptors may guide formation of gut nervous system in zebrafish
Fish lacking functional copies of the receptors have fewer enteric neurons than usual, but the findings await further validation.