Social difficulties

Recent articles

Two surreal heads touch each other’s faces.

The case for redefining ‘theory of mind’: Q&A with François Quesque

In a new commentary, Quesque and 44 experts in neuroscience and psychology propose a standardized lexicon for research on the attribution of mental states.

By Lauren Schenkman
10 October 2024 | 7 min read
Stock photograph of a women and her young child at a clinician’s office.

A genetics-first clinic for catching developmental conditions early: Q&A with Jacob Vorstman

A new clinic is assessing children who have a genetic predisposition for autism and other neurodevelopmental conditions—sometimes before traits appear.

By Lauren Schenkman
15 August 2024 | 7 min read
Black-and-white research image of brain organoids.

Brain organoid size matches intensity of social problems in autistic people

Overgrown organoids could point to mechanisms underlying profound autism.

By Holly Barker
18 July 2024 | 5 min read
A research image of X chromosomes with Fragile X syndrome

Understanding fragile X syndrome

Just in time for Fragile X Awareness Month, The Transmitter rounds up notable coverage.

By Daisy Yuhas
4 July 2024 | 2 min read
A research image of a mouse brain

Immune-activation model mice escape infantile amnesia, retain early memories

Male pups born to mothers treated with immune-stimulating molecules show autism-like behaviors and, unlike wildtype animals, do not lose memories formed during early life.

By Giorgia Guglielmi
11 January 2024 | 5 min read

Autism research hits the road

Some scientists are thinking creatively about how to collect data in flexible environments and meet communities where they’re at.

By Giorgia Guglielmi
8 December 2023 | 0 min watch
A person stands in front of a neatly organized dresser drawer.

Teasing apart insistence on sameness with Mirko Uljarević

The hallmark autism trait has multiple facets, Uljarević and his colleagues have found.

By Lauren Schenkman
30 October 2023 | 6 min read
A research image of a mouse hippocampus

Some social issues in DYRK1A model mice stem from faulty inhibitory circuits

Alterations in inhibitory circuits and difficulties in social recognition characterize mice missing one copy of DYRK1A, a gene linked to autism.

By Giorgia Guglielmi
11 October 2023 | 4 min read
A young boy sits alone on a bench in a playground.

Mental health issues emerge with shifts in autism traits across childhood

Anxiety and other challenges autistic children experience may stem from an increase in social-communication issues and a decrease in repetitive behaviors from ages 6 to 11.

By Charles Q. Choi
27 September 2023 | 3 min read
An illustration of Evodkia Anagnastou

Evdokia Anagnostou and the concept of a good life

The Holland Bloorview clinician and research director discusses how growing up on a small island shaped her career and the existential questions that keep her up at night.

By Brady Huggett
1 September 2023 | 77 min listen

Explore more from The Transmitter

Autism prevalence increasing in children, adults, according to electronic medical records

The uptick from 2011 to 2022 in the United States underscores a need for more services and research, the investigators say.

By Shaena Montanari
21 November 2024 | 2 min read

Immune cell interlopers breach—and repair—brain barrier in mice

The choroid plexus, the protective network of blood vessels and epithelial cells that line the brain’s ventricles, recruits neutrophils and macrophages during inflammation, a new study shows.

By Claudia López Lloreda
20 November 2024 | 6 min read

Expanding set of viral tools targets almost any brain cell type

Harmless viruses that encase short noncoding DNA elements called enhancers enable cell-type-specific gene delivery across the central nervous system in rodents and primates.

By Holly Barker
19 November 2024 | 2 min watch