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Recent articles
Untangling biological threads from autism’s phenotypic patchwork reveals four core subtypes
People belonging to the same subtype share genetic variants, behaviors and often co-occurring diagnoses, according to a new preprint.
Untangling biological threads from autism’s phenotypic patchwork reveals four core subtypes
People belonging to the same subtype share genetic variants, behaviors and often co-occurring diagnoses, according to a new preprint.
Genome structure could be key factor in some forms of autism
Variants in DNA stretches that do not code for proteins may alter the genome’s 3D architecture, influencing the expression of distant genes linked to autism.
Genome structure could be key factor in some forms of autism
Variants in DNA stretches that do not code for proteins may alter the genome’s 3D architecture, influencing the expression of distant genes linked to autism.
Some who lack autism diagnosis carry variants tied to the condition
The variants are associated with slight differences in measures of intelligence, income and employment, but the relationship may not be causal.
Some who lack autism diagnosis carry variants tied to the condition
The variants are associated with slight differences in measures of intelligence, income and employment, but the relationship may not be causal.
Null and Noteworthy: Modified MRI; father findings
This month’s newsletter tackles null findings from an attempted replication of a “revolutionary” MRI approach and an analysis of family genetics.
Null and Noteworthy: Modified MRI; father findings
This month’s newsletter tackles null findings from an attempted replication of a “revolutionary” MRI approach and an analysis of family genetics.
X-chromosome variants help explain autism’s sex bias
The rare variants are also linked to ADHD and Tourette syndrome, two other conditions that disproportionately affect boys and men.
X-chromosome variants help explain autism’s sex bias
The rare variants are also linked to ADHD and Tourette syndrome, two other conditions that disproportionately affect boys and men.
Scans of sundry variant types uncover autism-linked genes
Troves of sequencing data reveal genes tied to autism through different variant types, providing a more complete picture of the condition’s genetic roots and new clues to its heterogeneity.
Scans of sundry variant types uncover autism-linked genes
Troves of sequencing data reveal genes tied to autism through different variant types, providing a more complete picture of the condition’s genetic roots and new clues to its heterogeneity.
Mutations disrupting chromatin interactions contribute to autism
The mutations occur spontaneously in noncoding stretches of DNA that control gene expression.
Mutations disrupting chromatin interactions contribute to autism
The mutations occur spontaneously in noncoding stretches of DNA that control gene expression.
The final frontier: Autism geneticists take on the noncoding genome
The vast stretches of DNA that don't code for proteins could fill key knowledge gaps about autism genetics. But making sense of it all won't be easy.
The final frontier: Autism geneticists take on the noncoding genome
The vast stretches of DNA that don't code for proteins could fill key knowledge gaps about autism genetics. But making sense of it all won't be easy.
Common inherited variants tied to autism show sex bias in families
Siblings of autistic females are more likely to have autism than siblings of autistic males are, and mothers of autistic children carry more common, autism-linked variants than fathers do.
Common inherited variants tied to autism show sex bias in families
Siblings of autistic females are more likely to have autism than siblings of autistic males are, and mothers of autistic children carry more common, autism-linked variants than fathers do.
Spectrum of variants contribute differently to autism traits
Different combinations of common, rare, inherited and spontaneous mutations may explain why traits vary so widely among autistic people.
Spectrum of variants contribute differently to autism traits
Different combinations of common, rare, inherited and spontaneous mutations may explain why traits vary so widely among autistic people.
Explore more from The Transmitter
Newly awarded NIH grants for neuroscience lag 77 percent behind previous nine-year average
Since President Donald Trump took office on 20 January, the National Institute of Neurological Disease and Stroke and the National Institute of Mental Health have awarded one quarter as many new grants as during the same two-month period, on average, since 2016.
Newly awarded NIH grants for neuroscience lag 77 percent behind previous nine-year average
Since President Donald Trump took office on 20 January, the National Institute of Neurological Disease and Stroke and the National Institute of Mental Health have awarded one quarter as many new grants as during the same two-month period, on average, since 2016.
Releasing the Hydra with Rafael Yuste
Losing HHMI Investigator status caused Yuste to study neural networks in a new way.
Releasing the Hydra with Rafael Yuste
Losing HHMI Investigator status caused Yuste to study neural networks in a new way.
Coding error caused layoffs at National Institute of Neurological Disorders and Stroke this week, source says
Thirty employees—including 11 lab heads—at the institute should “immediately return to work,” according to an email the institute’s Office of Human Resources sent to top administration at the institute Wednesday evening.
Coding error caused layoffs at National Institute of Neurological Disorders and Stroke this week, source says
Thirty employees—including 11 lab heads—at the institute should “immediately return to work,” according to an email the institute’s Office of Human Resources sent to top administration at the institute Wednesday evening.