SALK 2013

Recent articles

Spectrum from The Transmitter.

Network of protein variants suggests new autism genes

Researchers have created a network of various forms of many proteins linked to autism, revealing new molecular interactions that may play a role in the disorder. The unpublished work was presented in a poster last week at the Salk Institute, Fondation IPSEN and Nature Symposium on Biological Complexity in La Jolla, California.

By Sarah DeWeerdt
25 January 2013 | 3 min read
Spectrum from The Transmitter.

Fragile X mice show brain-wave abnormalities during sleep

Neurons in mice that model fragile X syndrome show immature, overexcitable firing patterns, particularly during sleep, according to unpublished research presented last week at the Salk Institute, Fondation IPSEN and Nature Symposium on Biological Complexity in La Jolla, California.

By Sarah DeWeerdt
25 January 2013 | 3 min read
Spectrum from The Transmitter.

Eye movement, motor difficulties linked in autism

Problems with eye movements in people with autism are part of their motor difficulties and may contribute to the social deficits characteristic of the disorder, according to unpublished research presented last week at the Salk Institute, Fondation IPSEN and Nature Symposium on Biological Complexity in La Jolla, California.

By Sarah DeWeerdt
24 January 2013 | 3 min read
Spectrum from The Transmitter.

Autism-linked protein differs in male and female brains

The autism-linked protein MET is expressed at lower levels in the brains of men with autism than in control brains, according to unpublished research presented Thursday at the Salk Institute, Fondation IPSEN and Nature Symposium on Biological Complexity in La Jolla, California. Women with autism do not differ from healthy controls, however.

By Sarah DeWeerdt
24 January 2013 | 4 min read
Spectrum from The Transmitter.

Alzheimer’s drug aids autism mouse model

Memantine, a drug used to treat Alzheimer’s disease, can reverse autism-like features in mice lacking one copy of the MEF2C gene, according to a poster presented last week at the Salk Institute, Fondation IPSEN and Nature Symposium on Biological Complexity in La Jolla, California.

By Sarah DeWeerdt
23 January 2013 | 2 min read
Spectrum from The Transmitter.

Childhood-onset schizophrenia, autism share genetic links

Individuals who have childhood-onset schizophrenia carry more DNA deletions and duplications associated with other disorders, such as autism, than their unaffected siblings do. The unpublished research was presented 16 January at the Salk Institute, Fondation IPSEN and Nature Symposium on Biological Complexity in La Jolla, California.

By Sarah DeWeerdt
23 January 2013 | 4 min read

Explore more from The Transmitter

Colorful illustration of a latticework of proteins.

Cracking the code of the extracellular matrix

Despite evidence for a role in plasticity and other crucial functions, many neuroscientists still view these proteins as “brain goop.” The field needs technical advances and a shift in scientific thinking to move beyond this outdated perspective.

By Anna Victoria Molofsky
17 January 2025 | 5 min read
A repeated DNA strand extends farther from the left side of the image with each iteration.

Huntington’s disease gene variants past a certain size poison select cells

The findings—providing “the next step in the whole pathway”—help explain the disease’s late onset and offer hope that it has an extended therapeutic window.

By Angie Voyles Askham
16 January 2025 | 6 min read
Research image highlighting different brain regions.

X marks the spot in search for autism variants

Genetic variants on the X chromosome, including those in the gene DDX53, contribute to autism’s gender imbalance, two new studies suggest.

By Holly Barker
16 January 2025 | 6 min read