Purkinje cells

Recent articles

A slice of a cerebellum.

Mutation in top autism-linked gene may alter eye reflex

The discovery could help clinicians diagnose children who carry mutations in the gene, called SCN2A, and gauge their responses to potential therapies.

By Charles Q. Choi
26 February 2024 | 5 min read
Illustration of hybrid objects: part light bulb, part lab vial, some in blue and some in red to signify null and replicated results.

Null and Noteworthy: Brain aging, oxytocin pathways, biomarker back-up

Null and replicated results in this month’s newsletter tackle aging, a purported pathway for oxytocin’s effects on autistic people, and a possible autism biomarker.

By Emily Harris
15 September 2022 | 5 min read

Mouse study links dopamine in cerebellum to social behavior

The signaling molecule’s social role in the ‘little brain’ involves Purkinje neurons in the Crus I and Crus II regions, a new study reveals.

By Sarah DeWeerdt
6 July 2022 | 5 min read

Mice missing key clock gene show autism-like traits

A new study is the first to link social, repetitive and motor behaviors to mutations in BMAL1, which regulates the body’s circadian rhythms.

By Laura Dattaro
28 April 2022 | 5 min read

Autism model mice develop typical social and motor behaviors after drug treatment

The drug suppresses an overactive signaling pathway implicated in tuberous sclerosis complex.

By Laura Dattaro
9 March 2022 | 5 min read
lab mice

Mice with autism-related mutations show brain signaling imbalance

Mutations in POGZ, a gene strongly linked to autism, lead to a signaling imbalance in multiple brain regions in mice, according to two new studies.

By Angie Voyles Askham
4 January 2021 | 7 min read
Illustration showing the human brain with neurons made out of flower shapes and the cerebellum highlighted in gold and yellow.

Brain’s motor hub plays unsung role in social skills, cognition

Long known as the director of movement, the cerebellum may also coordinate social and cognitive abilities, including those central to autism.

By Sarah DeWeerdt
9 March 2020 | 7 min read

Fake autism claim; knocking out anesthesia; haunting milestone and more

Despite social media rumors, a British children’s television show does not cause autism; childhood anesthesia is not tied to autism risk; and an adult on the spectrum reaches a haunting milestone

By Emily Willingham
23 February 2018 | 5 min read
four brains with the RCrusl section highlighted

Study of cerebellum’s role in autism homes in on ‘social’ region

New evidence from both people and mice points to a part of the cerebellum that helps process social information as being critical in autism.

By Hannah Furfaro
18 December 2017 | 5 min read
Spectrum from The Transmitter.

Timed cues create mini-cerebellum in culture

Researchers can coax human stem cells to grow into layered structures that mimic the brain’s center for motor control, the cerebellum.

By Maris Fessenden
25 February 2015 | 3 min read

Explore more from The Transmitter

Five things to know if your federal grant is terminated

If you want to appeal the decision, know the rules that govern terminations, as well as the specific rationale given in your notice, science policy experts say.

By Calli McMurray
2 April 2025 | 7 min read

It’s time to examine neural coding from the message’s point of view

In studying the brain, we almost always take the neuron’s perspective. But we can gain new insights by reorienting our frame of reference to that of the messages flowing over brain networks.

By Daniel Graham
1 April 2025 | 0 min watch
Illustration of an open journal featuring lines of text and small illustrations of eyes and mouths.

Autism traits, mental health conditions interact in sex-dependent ways in early development

Here is a roundup of autism-related news and research spotted around the web for the week of 31 March.

By Jill Adams
1 April 2025 | 2 min read