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Recent articles

Synaptic protein’s shape-shifting skills propel plasticity

SYNGAP supports learning without tapping its eponymous “GAP” enzymatic activity, according to a new study.

By Angie Voyles Askham
29 February 2024 | 0 min watch

Signaling pathways link autism, schizophrenia

Autism, schizophrenia and intellectual disability share underlying deficits in pathways that regulate how the brain encodes new experiences, says Jason Shepherd.

By Jason Shepherd
27 May 2014 | 5 min read

High-throughput screen finds genes that link neurons

A new algorithm allows researchers to search among hundreds of genes and identify those involved in building synapses, the junctions that transmit signals between neurons, according to a report published 14 March in PLoS One.

By Jessica Wright
30 April 2014 | 1 min read

Fluorescent proteins shine new light on cells

Researchers have found a new way to light up proteins in living cells, revealing the connections between neurons, according to a study published 19 June in Neuron.

By Jessica Wright
17 July 2013 | 2 min read

Molecular mechanisms: Rats could model autism gender bias

Prenatal exposure of rats to the epilepsy drug valproic acid leads to behavioral and brain features that resemble autism, in males more than in females, according to a study published in the March issue of the Journal of Neurochemistry.

By Jessica Wright
9 April 2013 | 3 min read

Molecular mechanisms: Pruning path links autism, fragile X

The protein lacking in fragile X syndrome works with three autism-linked proteins to fine-tune the connections between neurons, according to a study published 21 December in Cell.

By Jessica Wright
1 February 2013 | 1 min read

Rett syndrome-linked gene maintains neuronal connections

A gene linked to some types of Rett syndrome is needed for the stability of connections between neurons, according to research published 4 September in Nature Cell Biology.

By Emily Singer
10 September 2012 | 4 min read

Molecular mechanisms: Autism gene tied to neuronal junctions

Neurobeachin, or NBEA, an autism–associated gene, may regulate the transport of signaling molecules to neuronal branches, according to a study published 22 November in Nature Communications.

By Jessica Wright
24 January 2012 | 3 min read

Molecular mechanisms: SHANK2 mutants alter synapses

Three mutations in SHANK2, an autism-associated gene, each lead to abnormal synapses, the junctions between neurons, according to a study in Human Molecular Genetics.

By Jessica Wright
30 November 2011 | 3 min read

Molecular mechanisms: Fragments of RNA regulate synapse

Small fragments of RNA, called microRNAs, can fine-tune the levels of proteins at the junctions between neurons in response to cell signals, according to a study published 10 June in Molecular Cell.

By Jessica Wright
27 July 2011 | 2 min read

Explore more from The Transmitter

Illustration of a shrew, sandpiper, locust, axolotl, monarch butterfly, African killifish, naked mole rat, octopus, bat and cichlid.

The non-model organism “renaissance” has arrived

Meet 10 neuroscientists bringing model diversity back with the funky animals they study.

Assembloids illuminate circuit-level changes linked to autism, neurodevelopment

These complex combinations of organoids afford a closer look at how gene alterations affect certain brain networks.

By Sarah DeWeerdt
19 December 2024 | 0 min watch
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Rajesh Rao reflects on predictive brains, neural interfaces and the future of human intelligence

Twenty-five years ago, Rajesh Rao proposed a seminal theory of how brains could implement predictive coding for perception. His modern version zeroes in on actions.

By Paul Middlebrooks
18 December 2024 | 97 min listen