Prefrontal cortex
Recent articles
Newfound gene network controls long-range connections between emotional, cognitive brain areas
The finding could help unravel gene regulatory networks and explain how genetic and environmental factors interact in neurodevelopmental conditions.
Newfound gene network controls long-range connections between emotional, cognitive brain areas
The finding could help unravel gene regulatory networks and explain how genetic and environmental factors interact in neurodevelopmental conditions.
Neurons’ spikes may convey their whereabouts
The time lag between spurts of activity holds anatomical information, according to a preprint.
Neurons’ spikes may convey their whereabouts
The time lag between spurts of activity holds anatomical information, according to a preprint.
Synaptic anomalies in autistic people support imbalance hypothesis
Increased excitatory and decreased inhibitory synapses in the prefrontal cortex of autistic people suggest broader impacts on brain function and connectivity.
Synaptic anomalies in autistic people support imbalance hypothesis
Increased excitatory and decreased inhibitory synapses in the prefrontal cortex of autistic people suggest broader impacts on brain function and connectivity.
Preprint questions validity of postmortem brain studies
But the alternatives, including living-brain biopsies, raise logistical and ethical questions, experts say.
Preprint questions validity of postmortem brain studies
But the alternatives, including living-brain biopsies, raise logistical and ethical questions, experts say.
People’s perceptions of ‘social’ animations don’t always square with researchers’ labels
The finding calls into question differences between autistic and non-autistic people on a decades-old theory-of-mind test involving interacting geometric shapes.
People’s perceptions of ‘social’ animations don’t always square with researchers’ labels
The finding calls into question differences between autistic and non-autistic people on a decades-old theory-of-mind test involving interacting geometric shapes.
Neurons struggle to spike without fragile X gene
FMR1 loss impairs sodium channels, hindering mouse neurons from generating the electrical signals needed to transmit information.
Neurons struggle to spike without fragile X gene
FMR1 loss impairs sodium channels, hindering mouse neurons from generating the electrical signals needed to transmit information.
Multi-omics study captures CNTNAP2’s far-ranging effects
The in-depth approach shows mutations in the autism-linked gene disrupt neuronal growth and communication, as well as mitochondrial gene expression.
Multi-omics study captures CNTNAP2’s far-ranging effects
The in-depth approach shows mutations in the autism-linked gene disrupt neuronal growth and communication, as well as mitochondrial gene expression.
Autism-linked mutation disrupts brain circuit to change social behavior
Therapies that target the circuit could boost social activity, new findings suggest.
Autism-linked mutation disrupts brain circuit to change social behavior
Therapies that target the circuit could boost social activity, new findings suggest.
Histone-modifying drug improves autism-like behaviors in mice
The experimental compound, called GSK-LSD1, enhances social preferences and reduces repetitive grooming in mice, according to a new study.
Histone-modifying drug improves autism-like behaviors in mice
The experimental compound, called GSK-LSD1, enhances social preferences and reduces repetitive grooming in mice, according to a new study.
Brain’s sensory switchboard has complex connections to autism
An atypical thalamus may underlie not only sensory issues in autism but also difficulties with social skills, attention and memory.
Brain’s sensory switchboard has complex connections to autism
An atypical thalamus may underlie not only sensory issues in autism but also difficulties with social skills, attention and memory.
Explore more from The Transmitter
Assembloids illuminate circuit-level changes linked to autism, neurodevelopment
These complex combinations of organoids afford a closer look at how gene alterations affect certain brain networks.
Assembloids illuminate circuit-level changes linked to autism, neurodevelopment
These complex combinations of organoids afford a closer look at how gene alterations affect certain brain networks.
Rajesh Rao reflects on predictive brains, neural interfaces and the future of human intelligence
Twenty-five years ago, Rajesh Rao proposed a seminal theory of how brains could implement predictive coding for perception. His modern version zeroes in on actions.
Rajesh Rao reflects on predictive brains, neural interfaces and the future of human intelligence
Twenty-five years ago, Rajesh Rao proposed a seminal theory of how brains could implement predictive coding for perception. His modern version zeroes in on actions.
In memoriam: Yves Frégnac, influential and visionary French neuroscientist
Frégnac, who died on 18 October at the age of 73, built his career by meeting neuroscience’s complexity straight on.
In memoriam: Yves Frégnac, influential and visionary French neuroscientist
Frégnac, who died on 18 October at the age of 73, built his career by meeting neuroscience’s complexity straight on.