Plasticity

Recent articles

Illustration of a mouse melting in front of a fan.

To beat the heat, hypothalamus neurons in mice ramp up their firing

The uptick may help the rodents acclimate to temperature hikes and keep their cool.

By Calli McMurray
11 December 2024 | 7 min read
Illustration of a pen hovering over a gene sequence-like series of colored rectangles.

This paper changed my life: ‘Histone demethylation mediated by the nuclear amine oxidase homolog LSD1,’ from the Shi Lab

This paper defined key rules of epigenomic regulation and shaped how I study chromatin plasticity as a mechanism for experience-dependent changes in the brain.

By Anne E. West
27 November 2024 | 5 min read
Research image of different interneuron subtypes responding to the absence of pyramidal neurons in the mouse cortex.

As circuits wire up, interneurons take cues from surrounding cells

The inhibitory cells’ development, diversity and abundance in the cortex is directed in part by pyramidal cells, a new preprint suggests.

By Olivia Gieger
14 August 2024 | 5 min read
Illustration of a canyon landscape with an orange clock face in place of a sun.

How to teach this paper: ‘Behavioral time scale synaptic plasticity underlies CA1 place fields,’ by Bittner and Milstein et al. (2017)

Katie Bittner, Aaron Milstein and their colleagues found that cellular learning can happen over longer timescales than Hebb’s rule predicts. How long should we wait to teach students about this phenomenon?

By Ashley Juavinett
24 June 2024 | 11 min read
Illustrated portrait of Eve Marder

Eve Marder, neural circuits and being heard

The National Medal of Science winner explains why she built her career around the crustacean and what it was like attending high school in a Hudson River town.

By Brady Huggett
1 June 2024 | 79 min listen

The question of regeneration—an excerpt from ‘Periphery: How Your Nervous System Predicts and Protects Against Disease’

In his recent book, Moses Chao makes the case that the peripheral nervous system can warn of future illnesses.

By Moses V. Chao
26 April 2024 | 7 min read

Neurons making memories shush their neighbors

When neurons strengthen their synapses, they “infect” surrounding cells with a virus-like protein to weaken those cells’ excitatory connections, according to a new preprint.

By Holly Barker
22 March 2024 | 5 min read
Photograph of a gloved hand pointing to a computer screen that is displaying an image of a mouse brain.

Going deep: The Transmitter’s top long-form stories in 2023

Our favorite features and book excerpts from the past year delved into the neurobiology of cancer; problems with survey data; free will; mathematical minds; and questions around one startup’s quest to treat brain conditions with cell therapies.

By The Transmitter
26 December 2023 | 4 min read
An abstract illustration of a figure from the shoulders up with multi-colored boxes on its face

What ‘drifting representations’ reveal about the brain

How neuronal activity patterns associated with a behavior can change, even when the behavior does not — something once seen as an experimental artifact — could offer new insights about neural function.

By Angie Voyles Askham
13 December 2023 | 8 min read
Close-up of a green glass slide embedded with dozens of tiny electrodes.

Making cancer nervous

Nerve cells in the brain and throughout the body can turbocharge tumor growth — a finding that not only expands conventional ideas about the nervous system but points to novel therapeutic targets for a range of malignancies.

By Sarah DeWeerdt
13 November 2023 | 25 min listen

Explore more from The Transmitter

Illustration of distorted lines of different colors being pulled into a box where they are smoothed in a single multicolored line.

The Transmitter’s favorite essays and columns of 2024

From sex differences in Alzheimer’s disease to enduring citation bias, experts weighed in on important scientific and practical issues in neuroscience.

By The Transmitter
23 December 2024 | 2 min read
A curly line connects two pencils that are hovering over overlapping speech bubbles.

Say what? The Transmitter’s top quotes of 2024

“We’ve cured mouse-heimer’s thousands of times...”—find out who said this to a Transmitter reporter, and read our other favorite quotes from the past year.

By The Transmitter
23 December 2024 | 2 min read
Four microphones on a table with speech bubbles above them.

The Transmitter’s favorite podcasts of 2024

Our picks include a deep dive into dopamine, the role of PKMzeta in memory, and studying the stomatogastric ganglion.

By The Transmitter
23 December 2024 | 1 min read