Perspectives

Recent articles

Expert opinions on trends and controversies in neuroscience

Research image of an assembloid.

Organoids and assembloids offer a new window into human brain

These sophisticated 3D cultures reveal previously inaccessible stages of human brain development and enable the systematic study of disease genes.

By Sergiu P. Pasca
31 March 2025 | 6 min read
University of Puerto Rico building.

The future of neuroscience research at U.S. minority-serving institutions is in danger

Cuts to federally funded programs present an existential crisis for the University of Puerto Rico’s rich neuroscience community and for research at minority-serving institutions everywhere.

By Carmen S. Maldonado-Vlaar
28 March 2025 | 5 min read
University of Puerto Rico building.

El futuro de la investigación neurocientífica en instituciones que sirven minorías está en peligro

Los recortes a los programas financiados con fondos federales representan una crisis existencial para la rica comunidad neurocientífica de la Universidad de Puerto Rico y para la investigación en instituciones que atienden a minorías en todo Estados Unidos.

By Carmen S. Maldonado-Vlaar
28 March 2025 | 7 min read
Data streams into a transparent box.

Accepting “the bitter lesson” and embracing the brain’s complexity

To gain insight into complex neural data, we must move toward a data-driven regime, training large models on vast amounts of information. We asked nine experts on computational neuroscience and neural data analysis to weigh in.

By Eva Dyer, Blake Richards
26 March 2025 | 8 min read
Illustration of a face covered by several black rectangles.

Keep sex as a biological variable: Don’t let NIH upheaval turn back the clock on scientific rigor

Even in the absence of any formal instruction to do so, we should continue to hold our ourselves and our neuroscience colleagues accountable for SABV practices.

By Rebecca Shansky
25 March 2025 | 7 min read
Research image of cell types in the human brain.

Single-cell genomics technologies and cell atlases have ushered in a new era of human neurobiology

Single-cell approaches are already shedding light on the human brain, identifying cell types that are most vulnerable in the early stages of Alzheimer’s disease, for example.

By Ed Lein, Hongkui Zeng
24 March 2025 | 7 min read
Illustration of a woman sitting on a branch with a singing bird.

This paper changed my life: Stephanie Palmer on the ties between human speech and birdsong—and her ‘informal life coach’

A groundbreaking review by Allison Doupe, who was Palmer’s mentor, and Patricia Kuhl helped shape the field’s understanding of the neural and evolutionary dynamics of speech.

By Stephanie Palmer
18 March 2025 | 5 min read
Tiger in a brain scanner.

Lions and tigers and bears: Long-lived zoo animals offer a promising venue to study mental health and neurodegenerative disorders

These animals’ lifestyles often mirror those of people, making them a more relevant milieu than lab mice for determining how environmental factors influence mental health and cognitive decline. Studying them could improve animal welfare in the process.

By Christine J. Charvet
17 March 2025 | 5 min read
Composite of brain imaging techniques.

Thanks to new technologies, neuroscientists have more direct access to the human brain than ever before

Model systems continue to offer us tremendous insight, but it’s time for basic researchers to train their sights on the human brain. If I were starting my career today, I would focus on human neurobiology.

By Joshua R. Sanes
17 March 2025 | 7 min read
A geometric figure looks out on an abstract horizon.

The limits of neuroscience

Truly understanding the brain requires a set of conditions we’re unlikely to meet: that knowledge about the brain is finite, and that we have both access to that knowledge and the means to understand it.

By Mark Humphries
10 March 2025 | 8 min read

Explore more from The Transmitter

A red pencil sits on a stack of white paper.

Who funds your basic neuroscience research? Help The Transmitter compile a list of funding sources

We want to hear from you about the sources of funding for your research.

By Claudia López Lloreda
28 March 2025 | 1 min read
Astrocytes in a mouse brain.

Unexpected astrocyte gene flips image of brain’s ‘stalwart sentinels’

The genetic marker upends the accepted orientation of non-star-like astrocytes in the glia limitans superficialis.

By Lauren Schenkman
28 March 2025 | 5 min read
Illustration of a line graph emanating from a beaker.

Null and Noteworthy: Reexamining registered reports

Out of 92 preregistered studies that resulted in published papers, only 15 had fully adhered to their preregistration details, according to a new analysis.

By Laura Dattaro
28 March 2025 | 5 min read