Pain

Recent articles

Research image of the human dorsal root ganglion.

‘Unprecedented’ dorsal root ganglion atlas captures 22 types of human sensory neurons

The atlas also offers up molecular and cellular targets for new pain therapies.

By Calli McMurray
23 December 2025 | 5 min read
Close up of thumb and forefinger holding a transparent red and white capsule pill with a lab inside it.

How basic neuroscience has paved the path to new drugs

A growing list of medications—such as zuranolone for postpartum depression, suzetrigine for pain, and the gepants class of migraine medicines—exist because of insights from basic research.

By Alex Kwan
15 December 2025 | 6 min read

Ann Kennedy explains the theoretical neuroscience of survival behaviors

The Scripps neuroscientist calls for a broader theoretical neuroscience approach in her area of research, which focuses on how the subcortex bridges life and cognition.

By Paul Middlebrooks
24 September 2025 | 1 min read
Peggy Mason at her desk.

Up and out with Peggy Mason

Mason helped define the rodent prosocial behavior field, but now she’s changing course.

By Sydney Wyatt
15 August 2025 | 12 min read
Research image of the spinal meninges in mice.

Immune cells block pain in female mice only

Regulatory T cells in the spinal meninges release endogenous opioids in a sex-specific manner, new work shows.

By Angie Voyles Askham
22 May 2025 | 5 min read
Tic-tac-toe board with pills representing x’s and o’s.

Basic pain research ‘is not working’: Q&A with Steven Prescott and Stéphanie Ratté

Prescott and Ratté critique the clinical relevance of preclinical studies in the field and highlight areas for improvement.

By Sydney Wyatt
18 April 2025 | 7 min read
Research image of neurons in the rostral anterior cingulate cortex (right, in green) sending signals to cells in the pontine nucleus (left, in yellow) to quell pain.

Cerebellar circuit may convert expected pain relief into real thing

The newly identified circuit taps into the brain’s opioid system to provide a top-down form of pain relief.

By Angie Voyles Askham
24 July 2024 | 6 min read

Robots boost data consistency in rodent studies reliant on mechanical, optogenetic stimulation

Two new devices take experimenter variation out of the equation, the lead investigators say.

By Calli McMurray
15 May 2024 | 0 min watch

The question of regeneration—an excerpt from ‘Periphery: How Your Nervous System Predicts and Protects Against Disease’

In his recent book, Moses Chao makes the case that the peripheral nervous system can warn of future illnesses.

By Moses V. Chao
26 April 2024 | 7 min read
Research image of presynapses on sensory neurons in fruit flies.

UBE3A’s link to synaptic pruning bolstered by fly study

Increasing or reducing the levels of the UBE3A gene, which is associated with autism and autism-related syndromes, results in altered patterns of synaptic pruning — a process that snips away brain cell connections.

By Giorgia Guglielmi
28 September 2023 | 5 min read

Explore more from The Transmitter

Illustration of an open journal featuring lines of text and small illustrations of eyes and mouths.

Interneurons’ role in epilepsy, and more

Here is a roundup of autism-related news and research spotted around the web for the week of 9 February.

By Jill Adams
10 February 2026 | 1 min read
Research image of neuronal proteins in mice.

Aging neurons outsource garbage disposal, clog microglia

Degradation-resistant proteins pass from neurons to glial cells in a process that may spread protein clumps around the brain, according to a study in mice.

By Holly Barker
10 February 2026 | 4 min read
Monkey against a soft, colorful background.

Oregon primate research center to negotiate with NIH on possible transition to sanctuary

The board of directors at Oregon Health & Science University, which runs the primate center, voted unanimously in favor of the move.

By Calli McMurray
9 February 2026 | 6 min read

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