Pain

Recent articles

Howard Fields.

In memoriam: Howard Fields, pain research pioneer

Over six decades, Fields mapped out the circuits of both pain and addiction.

By Natalia Mesa
22 May 2026 | 7 min read
Annette Dolphin.

Remembering Annette Dolphin, who helped explain gabapentin’s effects

The "intuitive" neuropharmacologist pushed against the status quo.

By Michael Eisenstein
13 March 2026 | 7 min read
Gloved hand reaches out to touch a mouse.

This paper changed my life: Ishmail Abdus-Saboor on balancing the study of pain and pleasure

A 2013 Nature paper from David Anderson’s lab revealed a group of sensory neurons involved in pleasurable touch and led Abdus-Saboor down a new research path.

By Ishmail Abdus-Saboor
13 February 2026 | 7 min read
Research image of the human dorsal root ganglion.

‘Unprecedented’ dorsal root ganglion atlas captures 22 types of human sensory neurons

The atlas also offers up molecular and cellular targets for new pain therapies.

By Calli McMurray
23 December 2025 | 5 min read
Close up of thumb and forefinger holding a transparent red and white capsule pill with a lab inside it.

How basic neuroscience has paved the path to new drugs

A growing list of medications—such as zuranolone for postpartum depression, suzetrigine for pain, and the gepants class of migraine medicines—exist because of insights from basic research.

By Alex Kwan
15 December 2025 | 6 min read

Ann Kennedy explains the theoretical neuroscience of survival behaviors

The Scripps neuroscientist calls for a broader theoretical neuroscience approach in her area of research, which focuses on how the subcortex bridges life and cognition.

By Paul Middlebrooks
24 September 2025 | 1 min read
Peggy Mason at her desk.

Up and out with Peggy Mason

Mason helped define the rodent prosocial behavior field, but now she’s changing course.

By Sydney Wyatt
15 August 2025 | 12 min read
Research image of the spinal meninges in mice.

Immune cells block pain in female mice only

Regulatory T cells in the spinal meninges release endogenous opioids in a sex-specific manner, new work shows.

By Angie Voyles Askham
22 May 2025 | 5 min read
Tic-tac-toe board with pills representing x’s and o’s.

Basic pain research ‘is not working’: Q&A with Steven Prescott and Stéphanie Ratté

Prescott and Ratté critique the clinical relevance of preclinical studies in the field and highlight areas for improvement.

By Sydney Wyatt
18 April 2025 | 7 min read
Research image of neurons in the rostral anterior cingulate cortex (right, in green) sending signals to cells in the pontine nucleus (left, in yellow) to quell pain.

Cerebellar circuit may convert expected pain relief into real thing

The newly identified circuit taps into the brain’s opioid system to provide a top-down form of pain relief.

By Angie Voyles Askham
24 July 2024 | 6 min read

Explore more from The Transmitter

Avis Cohen.

Remembering Avis H. Cohen, who bridged disciplines to decode lamprey locomotion

The founding director of the University of Maryland’s Neuroscience and Cognitive Science program brought neuroscience, math and engineering together.

By Sarah Thau
26 June 2026 | 8 min read
Photo collage featuring a portrait of Tempest McDonald.

When autistic kids grow up, Chapter 4: How did things unfold?

Tempest McDonald sues Vanderbilt University Medical Center through the Equal Employment Opportunity Commission. Her published NIH paper finds allies.

By Brady Huggett
25 June 2026 | 27 min listen
Researchers looking at KEMRI biobank vials.

NeuroDev study maps previously unseen genetic variation in Africa

The project is helping to fill critical gaps in the genetic underpinnings of autism and other neurodevelopmental conditions.

By Brianna Abbott
25 June 2026 | 5 min read