Open neuroscience and data-sharing

Recent articles

This series of scientist-written essays explores some of the benefits and challenges of data-sharing.

Illustration of a funnel taking abstract shapes in at the top and spouting an organized flow of shapes out at the bottom.

To keep or not to keep: Neurophysiology’s data dilemma

An exponential growth in data size presents neuroscientists with a significant challenge: Should we be keeping all raw data or focusing on processed datasets? I asked experimentalists and theorists for their thoughts.

By Nima Dehghani
25 November 2024 | 5 min read
Illustration of three figures standing in front of a grid of dots and a world map.

The S-index Challenge: Develop a metric to quantify data-sharing success

The NIH-sponsored effort aims to help incentivize scientists to share data. But many barriers to the widespread adoption of useful data-sharing remain.

By Loren Frank
8 October 2024 | 6 min listen
Illustration of three figures cleaning data with brooms and brushes.

A README for open neuroscience

Making data (and code) useful for yourself automatically makes it useful for others.

By Samuel Gershman
9 September 2024 | 5 min read
Illustration of a scientist attempting to wrangle many forms of data at once: a pile of charts and graphs threatens to knock them off of their feet as they attempt to prop it up.

Neuroscience graduate students deserve comprehensive data-literacy education

Despite growing requirements around how to handle and share data, formal training is lacking.

By Letisha R. Wyatt
15 July 2024 | 6 min read
Image of neural activity in a mouse as seen through the Miniscope.

Designing an open-source microscope

Funding for the development of open-source tools is on the rise, but support for their maintenance and dissemination, both crucial for their meaningful uptake, remains a major challenge.

By Daniel Aharoni
17 June 2024 | 6 min read
An illustration of a figure looking at a flow chart

Neuroscience needs a research-video archive

Video data are enormously useful and growing rapidly, but the field lacks a searchable, shareable way to store them.

By Robert Froemke
6 May 2024 | 6 min read
An abstract illustration of colorful lines on a yellow background

Pooling data points to new potential treatment for spinal cord injury

By gathering raw data from multiple labs, we identified an overlooked predictor of recovery after spinal cord injury. Many more insights remain trapped in scattered data.

By Adam Ferguson, Hannah Radabaugh, Abel Torres-Espin
4 March 2024 | 7 min read
An illustration of a diver assisting a scientist at a giant computer.

How scuba diving helped me embrace open science

Our lab adopted practices to make data- and code-sharing feel safer, including having the coding equivalent of a dive buddy. Trainees call the buddy system a welcome safety net.

By Ted Satterthwaite
19 February 2024 | 7 min read
Abstract illustration of antibodies scattered against a peach-colored background.

We found a major flaw in a scientific reagent used in thousands of neuroscience experiments — and we’re trying to fix it.

As part of that ambition, we launched a public-private partnership to systematically evaluate antibodies used to study neurological disease, and we plan to make all the data freely available.

By Mona AlQazzaz, Aled Edwards
5 February 2024 | 6 min read

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Explore more from The Transmitter

Research image of brain glucose levels in mice.

Food for thought: Neuronal fuel source more flexible than previously recognized

The cells primarily rely on glucose—rather than lactate from astrocytes—to generate energy, according to recent findings in mice.

By Giorgia Guglielmi
7 February 2025 | 6 min read
Abstract illustration of overlapping lines.

Claims of necessity and sufficiency are not well suited for the study of complex systems

The earliest studies on necessary and sufficient neural populations were performed on simple invertebrate circuits. Does this logic still serve us as we tackle more sophisticated outputs?

By Grace Lindsay
7 February 2025 | 6 min read
Research image of a mouse brain slice stained in purple and yellow.

Subthalamic plasticity helps mice squelch innate fear responses

When the animals learn that a perceived threat is not dangerous, long-term activity changes in a part of the subthalamus suppress their instinctive fears.

By Sydney Wyatt
6 February 2025 | 5 min read