Open neuroscience

Recent articles

fMRI scans exiting a grain silo.

To make a meaningful contribution to neuroscience, fMRI must break out of its silo

We need to develop research programs that link phenomena across levels, from genes and molecules to cells, circuits, networks and behavior.

By Avram Holmes
8 April 2025 | 6 min read
Data streams into a transparent box.

Accepting “the bitter lesson” and embracing the brain’s complexity

To gain insight into complex neural data, we must move toward a data-driven regime, training large models on vast amounts of information. We asked nine experts on computational neuroscience and neural data analysis to weigh in.

By Eva Dyer, Blake Richards
26 March 2025 | 8 min read
A group of scientists discusses in a lab.

Learning scientific rigor: Q&A with Konrad Kording and Hao Ye

The developers of a new open-access curriculum to teach rigor discuss confirmation bias and other common errors in scientific thinking, plus ways to avoid these missteps.

By Calli McMurray
19 March 2025 | 6 min read
Interconnected lines form a world map.

Science must step away from nationally managed infrastructure

Scientific data and independence are at risk. We need to work with community-driven services and university libraries to create new multi-country organizations that are resilient to political interference.

By Dan Goodman
20 February 2025 | 7 min read
Grid of human brain scans.

Dose, scan, repeat: Tracking the neurological effects of oral contraceptives

We know little about how the brain responds to oral contraceptives, despite their widespread use. I am committed to changing that: I scanned my brain 75 times over the course of a year and plan to make my data openly available.

By Carina Heller
20 January 2025 | 7 min read
A curly line connects two pencils that are hovering over overlapping speech bubbles.

Say what? The Transmitter’s top quotes of 2024

“We’ve cured mouse-heimer’s thousands of times...”—find out who said this to a Transmitter reporter, and read our other favorite quotes from the past year.

By The Transmitter
23 December 2024 | 2 min read
Illustration of an open book with the pages creating a brain shape, and with a tassel resembling a DNA sequence.

Open-access neuroscience comes to the classroom: Q&A with Liz Kirby

Neuroscience textbooks can be prohibitively expensive for some undergraduate students. A new open-access alternative seeks to change that.

By Francisco J. Rivera Rosario
13 December 2024 | 6 min read
Illustration of a funnel taking abstract shapes in at the top and spouting an organized flow of shapes out at the bottom.

To keep or not to keep: Neurophysiology’s data dilemma

An exponential growth in data size presents neuroscientists with a significant challenge: Should we be keeping all raw data or focusing on processed datasets? I asked experimentalists and theorists for their thoughts.

By Nima Dehghani
25 November 2024 | 5 min read
Illustration of three figures standing in front of a grid of dots and a world map.

The S-index Challenge: Develop a metric to quantify data-sharing success

The NIH-sponsored effort aims to help incentivize scientists to share data. But many barriers to the widespread adoption of useful data-sharing remain.

By Loren Frank
8 October 2024 | 6 min listen
Illustration of three figures cleaning data with brooms and brushes.

A README for open neuroscience

Making data (and code) useful for yourself automatically makes it useful for others.

By Samuel Gershman
9 September 2024 | 5 min read

Explore more from The Transmitter

People help each other climb up a supersized human brain.

As federal funders desert mentorship programs for marginalized students, trainee-led initiatives fill the gap

Grassroots organizations, led by graduate students and postdoctoral researchers, are stepping up to provide neuroscience career training and guidance for students from marginalized backgrounds—and they need your support.

By Christian Cazares, Maribel Patiño
11 April 2025 | 5 min read
Research image of two mouse brain slices.

Split gene therapy delivers promise in mice modeling Dravet syndrome

The new approach overcomes viral packaging limitations by delivering SCN1A piecemeal and stitching it together in target cells.

By Holly Barker
10 April 2025 | 5 min read
Screenshot of NeMO website with banner reading This repository is under review for potential modification in compliance with Administration directives.

U.S. human data repositories ‘under review’ for gender identity descriptors

Researchers associated with the repositories received an email from the U.S. National Institutes of Health in March noting that they must comply with a 20 January executive order from President Trump that recognizes only two sexes: male and female.

By Angie Voyles Askham
9 April 2025 | 4 min read