Null and Noteworthy
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A monthly newsletter about neuroscience research that fails to support a hypothesis or replicates a previously proposed one.
Null and Noteworthy: Reexamining registered reports
Out of 92 preregistered studies that resulted in published papers, only 15 had fully adhered to their preregistration details, according to a new analysis.
Null and Noteworthy: Reexamining registered reports
Out of 92 preregistered studies that resulted in published papers, only 15 had fully adhered to their preregistration details, according to a new analysis.
Null and Noteworthy, relaunched: Probing a schizophrenia biomarker
This edition of Null and Noteworthy—the first for The Transmitter—highlights new findings about the auditory steady-state response in people with schizophrenia that, all within one study, somehow packed in a null result and a failed replication.
Null and Noteworthy, relaunched: Probing a schizophrenia biomarker
This edition of Null and Noteworthy—the first for The Transmitter—highlights new findings about the auditory steady-state response in people with schizophrenia that, all within one study, somehow packed in a null result and a failed replication.
The true meaning of a null result
This edition of Null and Noteworthy highlights results that reveal the difficulty in drawing definitive conclusions from data, including new findings about epidurals that contradict several others and an apparent null result on sex differences that may derive from “circular logic.”
The true meaning of a null result
This edition of Null and Noteworthy highlights results that reveal the difficulty in drawing definitive conclusions from data, including new findings about epidurals that contradict several others and an apparent null result on sex differences that may derive from “circular logic.”
Prenatal exposures; Angelman trial suspension; autistic adult well-being
This month’s issue of the Null and Noteworthy newsletter breaks down some negative results involving prenatal exposures, an experimental treatment for Angelman syndrome, and the role that age at autism diagnosis plays in subsequent outcomes, and more.
Prenatal exposures; Angelman trial suspension; autistic adult well-being
This month’s issue of the Null and Noteworthy newsletter breaks down some negative results involving prenatal exposures, an experimental treatment for Angelman syndrome, and the role that age at autism diagnosis plays in subsequent outcomes, and more.
Null and Noteworthy: Modified MRI; father findings
This month’s newsletter tackles null findings from an attempted replication of a “revolutionary” MRI approach and an analysis of family genetics.
Null and Noteworthy: Modified MRI; father findings
This month’s newsletter tackles null findings from an attempted replication of a “revolutionary” MRI approach and an analysis of family genetics.
Null and Noteworthy: Arbaclofen results; another oxytocin edition
New data from clinical trials of arbaclofen and oxytocin underscore the murkiness of null results. Plus, researchers seek clarity on the neurodevelopmental effects of oxytocin during childbirth.
Null and Noteworthy: Arbaclofen results; another oxytocin edition
New data from clinical trials of arbaclofen and oxytocin underscore the murkiness of null results. Plus, researchers seek clarity on the neurodevelopmental effects of oxytocin during childbirth.
Null and Noteworthy: Reader response; cerebrospinal fluid; connectivity subgroups
In this edition of Null and Noteworthy, researchers upend early interventions and diagnostic boundaries.
Null and Noteworthy: Reader response; cerebrospinal fluid; connectivity subgroups
In this edition of Null and Noteworthy, researchers upend early interventions and diagnostic boundaries.
Detecting a signal amid noise in autism early-intervention research
Studies of behavioral treatments for autism are complex and can easily be misunderstood. Here we provide some guidance.
Detecting a signal amid noise in autism early-intervention research
Studies of behavioral treatments for autism are complex and can easily be misunderstood. Here we provide some guidance.
Null and Noteworthy: Registered reports; motor measurements; viral DNA
In this edition of Null and Noteworthy, Spectrum talks with a Nature editor about the journal’s move to publish more null results.
Null and Noteworthy: Registered reports; motor measurements; viral DNA
In this edition of Null and Noteworthy, Spectrum talks with a Nature editor about the journal’s move to publish more null results.
Null and Noteworthy: Busting biomarkers; going after GABA; reproducibility illusion
In this edition of Null and Noteworthy, scientists find little to be excited about in research on biomarkers for neurodevelopmental conditions.
Null and Noteworthy: Busting biomarkers; going after GABA; reproducibility illusion
In this edition of Null and Noteworthy, scientists find little to be excited about in research on biomarkers for neurodevelopmental conditions.
Explore more from The Transmitter
During decision-making, brain shows multiple distinct subtypes of activity
Person-to-person variability in brain activity might represent meaningful differences in cognitive processes, rather than random noise.
During decision-making, brain shows multiple distinct subtypes of activity
Person-to-person variability in brain activity might represent meaningful differences in cognitive processes, rather than random noise.
Basic pain research ‘is not working’: Q&A with Steven Prescott and Stéphanie Ratté
Prescott and Ratté critique the clinical relevance of preclinical studies in the field and highlight areas for improvement.
Basic pain research ‘is not working’: Q&A with Steven Prescott and Stéphanie Ratté
Prescott and Ratté critique the clinical relevance of preclinical studies in the field and highlight areas for improvement.
Proposed NIH budget cut threatens ‘massive destruction of American science’
A leaked draft of a Trump administration proposal includes an approximately 40 percent cut to the National Institutes of Health’s budget and a major reorganization of its 27 institutes and centers.
Proposed NIH budget cut threatens ‘massive destruction of American science’
A leaked draft of a Trump administration proposal includes an approximately 40 percent cut to the National Institutes of Health’s budget and a major reorganization of its 27 institutes and centers.