Mac Shine

Associate professor of computational systems neurobiology
University of Sydney

Mac Shine is associate professor of computational systems neurobiology in the Brain and Mind Centre at the University of Sydney in Australia. His lab focuses on mapping mechanistic neurobiological neural models to dynamical network signatures estimated from functional neuroimaging data.

Shine completed his Ph.D. in cognitive neuroscience at the University of Sydney. As a graduate student, he helped to refine the neural mechanisms of non-motor symptoms of Parkinson’s disease. As a postdoctoral fellow at Stanford University in California, Shine developed innovative approaches for tracking whole-brain network dynamics from noninvasive functional neuroimaging data. In 2017, he returned to the University of Sydney, where he runs a diverse research lab that creates neurobiological models of cognitive function. He is a joint National Health and Medical Research Council/Bellberry fellow.

From this contributor

Explore more from The Transmitter

Among brain changes studied in autism, spotlight shifts to subcortex

The striatum and thalamus are more likely than the cerebral cortex to express autism variants or bear transcriptional changes, two unpublished studies find.

By Holly Barker
11 December 2025 | 5 min read
Brain organoid.

What is the future of organoid and assembloid regulation?

Four experts weigh in on how to establish ethical guardrails for research on the 3D neuron clusters as these models become ever more complex.

By Claudia López Lloreda
10 December 2025 | 7 min read
Research image of variants of the ATPase subunit PSMC5/RPT6.

Insights on suicidality and autism; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 8 December.

By Jill Adams
9 December 2025 | 2 min read

privacy consent banner

Privacy Preference

We use cookies to provide you with the best online experience. By clicking “Accept All,” you help us understand how our site is used and enhance its performance. You can change your choice at any time. To learn more, please visit our Privacy Policy.