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The latest developments in neuroscience

Neuronal genes SATB2 and MEF2C.

Nuclear location helps control gene activity during brain development

A study of developing human brain tissue suggests that genes switch on more strongly when they move from the nucleus’s edge toward structures that contain proteins involved in making and processing RNA.

By Giorgia Guglielmi
20 August 2026 | 4 min read
Cortical organoids.

Five-year-old human brain organoids aged on schedule

The cultured spheres typically mimic only prenatal development, but the five-year-old ones grown in Paola Arlotta’s lab acquired postnatal features.

By Claudia López Lloreda
19 August 2026 | 5 min read

Brainstem neurons add new element to ‘already complex’ anxiety circuitry

Precise optogenetic modulation of a medullary neuron population reveals their role in anxiety-like behaviors.

By Sarah Thau
19 August 2026 | 0 min watch
Illustration of an open journal featuring lines of text and small illustrations of eyes and mouths.

Links between tuberous sclerosis complex and autism, and more

Here is a roundup of autism-related news and research spotted around the web for the week of 17 August.

By Jill Adams
18 August 2026 | 1 min read

Early experience reshapes zebrafish retinal cells, alters behavior

The cells undergo a classic form of plasticity previously thought to occur only in downstream visual circuits.

By Siddhant Pusdekar
13 August 2026 | 0 min watch
Research image of expression of MEIS2 in PV interneurons.

Loss of interneuron plasticity may be shared hallmark of neurodevelopmental conditions

Restoring an experience-dependent interneuron plasticity gene in adulthood improves memory and cuts seizures in CNTNAP2 knockout mice, a new study shows.

By Claudia López Lloreda
12 August 2026 | 5 min read
Structural MRI scans of people with Alzheimer’s disease and depression.

Neuropsychiatric MRI brain signatures fail reproducibility test

Small neuroimaging studies are unlikely to capture consistent anatomical changes related to conditions such as autism, schizophrenia and mood disorders, according to a new “wake-up call” study.

By Holly Barker
12 August 2026 | 5 min read
Research image of astrocytes.

Three models, three routes to altered auditory processing, and more

Here is a roundup of autism-related news and research spotted around the web for the week of 10 August.

By Jill Adams
11 August 2026 | 2 min read

Optimized two-photon microscopy enables voltage imaging at multiple depths

The tool could reveal how information flows within and between cortical layers during neural processing.

By Simon Makin
11 August 2026 | 4 min read

New findings begin to resolve theta sweep debate

Theta sweeps have been mired in controversy for decades, but the field is starting to converge on a consensus view of their function.

By Natalia Mesa
6 August 2026 | 1 min watch

Explore more from The Transmitter

Taylor Bolt photo illustration.

The fun and flexibility of data science

Taylor Bolt spent his Ph.D. and postdoc digging through brain imaging data for clues to cognition. In industry, the datasets are different but the joy of answering questions with data remains.

By Katie Moisse
18 August 2026 | 7 min read
Two trajectories cross over each other showing areas of alignment and misalignment.

Mind over metrics: How can we tell if two brains (or AI models) are alike?

The ability to record from large populations of neurons has triggered the development of myriad methods for comparing them. But we’re still grappling with how to convert measures of likeness into a better mechanistic understanding.

By Alex Williams
17 August 2026 | 7 min read