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Illustration of a shrew, sandpiper, locust, axolotl, monarch butterfly, African killifish, naked mole rat, octopus, bat and cichlid.

The non-model organism “renaissance” has arrived

Meet 10 neuroscientists bringing model diversity back with the funky animals they study.

Assembloids illuminate circuit-level changes linked to autism, neurodevelopment

These complex combinations of organoids afford a closer look at how gene alterations affect certain brain networks.

By Sarah DeWeerdt
19 December 2024 | 0 min watch
Illustration shows a solitary figure moving through a green and blue field of dots moving at different rates.

Explaining ‘the largest unexplained number in brain science’: Q&A with Markus Meister and Jieyu Zheng

The human brain takes in sensory information roughly 100 million times faster than it can respond. Neuroscientists need to explore this perceptual paradox to better understand the limits of the brain, Meister and Zheng say.

By Claudia López Lloreda
17 December 2024 | 8 min read
Research image of mouse neurons.

DDX3X gene function; gender diversity; lithium

Here is a roundup of autism-related news and research spotted around the web for the week of 16 December.

By Jill Adams
17 December 2024 | 2 min read
Research image of brain scans.

Impaired molecular ‘chaperone’ accompanies multiple brain changes, conditions

Rare genetic variants in a protein-folding complex contribute to a spectrum of phenotypes that encompass brain malformations, intellectual disability, autism and seizures, according to a new “hallmark” study.

By Holly Barker
12 December 2024 | 5 min read
Illustration of a mouse melting in front of a fan.

To beat the heat, hypothalamus neurons in mice ramp up their firing

The uptick may help the rodents acclimate to temperature hikes and keep their cool.

By Calli McMurray
11 December 2024 | 7 min read
Drawing by Santiago Ramón y Cajal of a hypothesis for how signals travel through neurons.

‘Sacred objects’ display discredits Golgi and Ramón y Cajal’s rivalry: Q&A with curator Daniel Colón Ramos

A new exhibit that opened last week shows drawings from the influential duo side by side for the first time and recasts them as collaborators. It also reveals lessons for modern scholars.

By Claudia López Lloreda
10 December 2024 | 7 min read
Research image of cerebellum damage in neonatal mice.

Genome folding; organelle changes; self-injury

Here is a roundup of autism-related news and research spotted around the web for the week of 9 December.

By Jill Adams
10 December 2024 | 2 min read
Research image of brain circuits.

Novel neurons upend ‘yin-yang’ model of hunger, satiety in brain

The new type of leptin-sensitive cells curb hunger quickly—adding to an increasingly complex picture of brain circuits that control feeding behaviors.

By Giorgia Guglielmi
9 December 2024 | 5 min read
A stack of dollar bills floats above the outline of a keyhole.

Howard Hughes Medical Institute to limit eligible universities for Investigator Program in bid to spread the wealth

The next round of competition, slated for late 2025, will have a new focus, according to an HHMI spokesperson.

By Shaena Montanari
6 December 2024 | 2 min read

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Rajesh Rao reflects on predictive brains, neural interfaces and the future of human intelligence

Twenty-five years ago, Rajesh Rao proposed a seminal theory of how brains could implement predictive coding for perception. His modern version zeroes in on actions.

By Paul Middlebrooks
18 December 2024 | 97 min listen
Portrait of Yves Fregnac.

In memoriam: Yves Frégnac, influential and visionary French neuroscientist

Frégnac, who died on 18 October at the age of 73, built his career by meeting neuroscience’s complexity straight on.

By Bahar Gholipour
18 December 2024 | 9 min read
High-resolution image of interconnected brain cells highlighted in magenta and blue.

What are recurrent networks doing in the brain?

The cortex is filled with excitatory local synapses, but we know little about their role in brain function. New experimental tools, along with ideas from artificial intelligence, are poised to change that.

By Mark Histed
16 December 2024 | 5 min read