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The latest developments in neuroscience

Research image of organoids derived from stem cell lines from people with intellectual disability, polymicroglia or microcephaly, alongside a control organoid.

New organoid atlas unveils four neurodevelopmental signatures

The comprehensive resource details data on microcephaly, polymicrogyria, epilepsy and intellectual disability from 352 people.

By Diana Kwon
17 December 2025 | 4 min read
Illustration of an open journal featuring lines of text and small illustrations of eyes and mouths.

Glutamate receptors, mRNA transcripts and SYNGAP1; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 15 December.

By Jill Adams
16 December 2025 | 2 min read
Research image visualizing brain waves.

Dispute erupts over universal cortical brain-wave claim

The debate highlights opposing views on how the cortex transmits information.

By Claudia López Lloreda
12 December 2025 | 5 min read

Waves of calcium activity dictate eye structure in flies

Synchronized signals in non-neuronal retinal cells draw the tiny compartments of a fruit fly’s compound eye into alignment during pupal development.

By Lauren Schneider
12 December 2025 | 0 min watch
Research image of human thalamus.

Among brain changes studied in autism, spotlight shifts to subcortex

The striatum and thalamus are more likely than the cerebral cortex to express autism variants or bear transcriptional changes, two unpublished studies find.

By Holly Barker
11 December 2025 | 5 min read
Brain organoid.

What is the future of organoid and assembloid regulation?

Four experts weigh in on how to establish ethical guardrails for research on the 3D neuron clusters as these models become ever more complex.

By Claudia López Lloreda
10 December 2025 | 7 min read
Research image of variants of the ATPase subunit PSMC5/RPT6.

Insights on suicidality and autism; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 8 December.

By Jill Adams
9 December 2025 | 2 min read
A stack of papers topped by many paper shreddings against a red background.

Exclusive: Springer Nature retracts, removes nearly 40 publications that trained neural networks on ‘bonkers’ dataset

The dataset contains images of children’s faces downloaded from websites about autism, which sparked concerns at Springer Nature about consent and reliability.

By Calli McMurray
8 December 2025 | 5 min read

Psilocybin rewires specific mouse cortical networks in lasting ways

Neuronal activity induced by the psychedelic drug strengthens inputs from sensory brain areas and weakens cortico-cortical recurrent loops.

By Siddhant Pusdekar
5 December 2025 | 0 min watch
Research image of parvalbumin expression in mice.

Plumbing the link between anti-CASPR2 antibodies and autism; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 1 December.

By Jill Adams
2 December 2025 | 1 min read

Explore more from The Transmitter

Can neuroscientists decode memories solely from a map of synaptic connections?

Five experts discuss the progress, possibilities and hurdles of decoding a “nontrivial” memory from an organism just by analyzing its brain connectivity patterns.

By Paul Middlebrooks
17 December 2025 | 1 min read
A scientist chases falling code with a butterfly net in a spare landscape with beautiful high clouds.

AI-assisted coding: 10 simple rules to maintain scientific rigor

These guidelines can help researchers ensure the integrity of their work while accelerating progress on important scientific questions.

By Russell Poldrack
16 December 2025 | 7 min read
Collage illustration of Shari Wiseman.

Frameshift: Shari Wiseman reflects on her pivot from science to publishing

As chief editor of Nature Neuroscience, Wiseman applies critical-thinking skills she learned in the lab to manage the journal’s day-to-day operations.

By Katie Moisse
15 December 2025 | 7 min read

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