Neurodegenerative disorders

Recent articles

Monkeys at Dutch primate center.

Dutch primate center awaits October animal research debate

Science is forging ahead at the Biomedical Primate Research Centre in the Netherlands, following a reversal of last year’s mandate to phase out primate studies. But researchers aren’t sure how long the reprieve will last.

By Lauren Schenkman
2 September 2026 | 5 min read
Stages of neurodegeneration: Neurofibrillary tangles at different stages of neurodegeneration are labeled with phosphorylated tau antibodies (green and blue).

Reimagining Mexico’s brain bank

Since Alzheimer’s disease researcher José Luna-Muñoz assumed leadership of the facility—Latin America’s oldest—in 2011, he has been acquiring additional tissue types and is working to expand donor recruitment to rural areas.

By Alejandra Manjarrez
28 August 2026 | 7 min read
Stages of neurodegeneration: Neurofibrillary tangles at different stages of neurodegeneration are labeled with phosphorylated tau antibodies (green and blue).

Reimaginando o banco de cérebros do México

Desde que o pesquisador da doença de Alzheimer José Luna-Muñoz assumiu a direção da instituição—a mais antiga da América Latina—em 2011, ele vem adquirindo novos tipos de tecido e trabalhando para ampliar o recrutamento de doadores nas áreas rurais

By Alejandra Manjarrez
28 August 2026 | 9 min read
Stages of neurodegeneration: Neurofibrillary tangles at different stages of neurodegeneration are labeled with phosphorylated tau antibodies (green and blue).

Reimaginando el banco de cerebros de México

Desde que el investigador de la enfermedad de Alzheimer José Luna-Muñoz se hizo cargo del banco de cerebros—el más antiguo de América Latina—en 2011, ha incorporado otros tipos de tejidos y trabaja para ampliar la captación de donantes a las zonas rurales.

By Alejandra Manjarrez
28 August 2026 | 9 min read
Burke Neurological Institute.

Exclusive: Brain and spinal cord institute halts research, citing funding problems

The Burke Neurological Institute, which calls itself “the only research institute in the U.S. dedicated to finding treatments to repair the brain and spinal cord,” ceased research operations on 22 May.

By Lauren Schenkman
4 June 2026 | 5 min read
Research image of brain cells involved with Amyotrophic lateral sclerosis (ALS) illuminated through genetic tools

Allen Institute sets sights on treatments for five brain diseases

The Brain Health Accelerator program aims to harness single-cell transcriptomics and cell-type-specific genetic tools to develop treatments for Alzheimer’s, Huntington’s and Parkinson’s diseases, Lewy body dementia and ALS.

By Calli McMurray
2 June 2026 | 5 min read
Research image of neuronal proteins in mice.

Aging neurons outsource garbage disposal, clog microglia

Degradation-resistant proteins pass from neurons to glial cells in a process that may spread protein clumps around the brain, according to a study in mice.

By Holly Barker
10 February 2026 | 5 min read
Nonhuman brain slice.

Nonhuman primate research to lose federal funding at major European facility

The Dutch Senate has ordered the Biomedical Primate Research Centre in the Netherlands to shift its funding away from primate experiments by 2030.

By Lauren Schenkman
30 October 2025 | 4 min read
Illustration of a neuron.

New questions around motor neurons and plasticity

A researcher’s theory hangs muscle degeneration on a broken neural circuit.

By David Adam
10 October 2025 | 9 min read
Illustration of complex, intersecting biological structures.

Everything, everywhere, all at once: Inside the chaos of Alzheimer’s disease

To truly understand Alzheimer’s disease, we may need to take a systems approach, in which inflammation, vascular injury, impaired glucose metabolism and other factors interact in complex ways.

By Michael A. Yassa
16 June 2025 | 7 min read

Explore more from The Transmitter

Cortical organoids from the anterior (green) or posterior (red) cortex.

Polarized cortical organoids mimic the brain’s regional organization

The organoids show region-specific gene-expression changes that match those observed during fetal development.

By Holly Barker
24 September 2026 | 4 min read
Research diagram of gene expression.

Prefrontal cortex has three transcriptomic acts across human lifespan, new atlas suggests

Various genes show distinct exits and entrances with age in the open-source dataset, the largest of its kind to date.

By Siddhant Pusdekar
23 September 2026 | 5 min read

Microglia scoop out garbage from inside neurons

Through a newly identified process called skoupocytosis, neurons recruit the immune cells to remove cellular waste they find hard to deal with themselves.

By Siddhant Pusdekar
23 September 2026 | 0 min watch