Neurodegenerative disorders

Recent articles

Burke Neurological Institute.

Exclusive: Brain and spinal cord institute halts research, citing funding problems

The Burke Neurological Institute, which calls itself “the only research institute in the U.S. dedicated to finding treatments to repair the brain and spinal cord,” ceased research operations on 22 May.

By Lauren Schenkman
4 June 2026 | 5 min read
Research image of brain cells involved with Amyotrophic lateral sclerosis (ALS) illuminated through genetic tools

Allen Institute sets sights on treatments for five brain diseases

The Brain Health Accelerator program aims to harness single-cell transcriptomics and cell-type-specific genetic tools to develop treatments for Alzheimer’s, Huntington’s and Parkinson’s diseases, Lewy body dementia and ALS.

By Calli McMurray
2 June 2026 | 5 min read
Research image of neuronal proteins in mice.

Aging neurons outsource garbage disposal, clog microglia

Degradation-resistant proteins pass from neurons to glial cells in a process that may spread protein clumps around the brain, according to a study in mice.

By Holly Barker
10 February 2026 | 5 min read
Nonhuman brain slice.

Nonhuman primate research to lose federal funding at major European facility

The Dutch Senate has ordered the Biomedical Primate Research Centre in the Netherlands to shift its funding away from primate experiments by 2030.

By Lauren Schenkman
30 October 2025 | 4 min read
Illustration of a neuron.

New questions around motor neurons and plasticity

A researcher’s theory hangs muscle degeneration on a broken neural circuit.

By David Adam
10 October 2025 | 9 min read
Illustration of complex, intersecting biological structures.

Everything, everywhere, all at once: Inside the chaos of Alzheimer’s disease

To truly understand Alzheimer’s disease, we may need to take a systems approach, in which inflammation, vascular injury, impaired glucose metabolism and other factors interact in complex ways.

By Michael A. Yassa
16 June 2025 | 7 min read

The brain’s quiet conductor: How hidden cells fine-tune arousal

New research published today suggests that the pericoeruleus acts as a kind of micromanager of arousal, selectively inhibiting different subgroups of locus coeruleus neurons depending on the behavioral context.

By Mac Shine
7 May 2025 | 59 min watch
Research image of human cortical neurons xenotransplanted into a mouse brain for months.

In vivo veritas: Xenotransplantation can help us study the development and function of human neurons in a living brain

Transplanted cells offer insight into human-specific properties, such as a lengthy cortical development and sensitivity to neurodevelopmental and neurodegenerative disease.

By Pierre Vanderhaeghen
7 April 2025 | 7 min read
Six different neurons.

Early trajectory of Alzheimer’s tracked in single-cell brain atlases

Inflammation in glia and the loss of certain inhibitory cells may kick off a disease cascade decades before diagnosis.

By Angie Voyles Askham
23 October 2024 | 8 min read
A collage illustration of a woman’s face fragmented by a mosaic of X chromosomes, lines and shapes.

Brains, biases and amyloid beta: Why the female brain deserves a closer look in Alzheimer’s research

New results suggest the disease progresses differently in women, but we need more basic science to unpack the mechanisms involved.

By Rachel Buckley
22 October 2024 | 7 min read

Explore more from The Transmitter

When autistic kids grow up, Chapter 5: The war dial

“You have to reshape the whole system.” Tempest McDonald earns a measure of peace.

By Brady Huggett
2 July 2026 | 42 min listen
Red note stuck in a stack of paper.

Scientists decry conference’s use of hidden prompts to snare AI peer reviews

The invisible messages, which instruct large language models to use telltale phrases in a peer-review report, are effective in catching artificial-intelligence misuse but also erode trust, some say.

By Dalmeet Singh Chawla
1 July 2026 | 4 min read

Johannes Jaeger explains why we should care that brains and AI are not the same

From single cells to whole organisms, living beings must continuously regenerate themselves and judge what's important to continue living. Artificial intelligence does not and cannot.

By Paul Middlebrooks
1 July 2026 | 1 min read