Myelin
Giant analysis reveals how autism-linked genes affect brain cell types
Genes that predispose people to autism account for a large portion of the neuronal and glial cell changes seen in those with the condition.
![Research illustration groups genes by their effects on brain cell types.](https://www.thetransmitter.org/wp-content/uploads/2024/06/fig-6a-1024x683.webp)
Giant analysis reveals how autism-linked genes affect brain cell types
Genes that predispose people to autism account for a large portion of the neuronal and glial cell changes seen in those with the condition.
Antihistamine aids myelination in Pitt-Hopkins mice
The drug clemastine and other compounds that fortify the protective sheath around neurons may prove therapeutic for some genetic neurodevelopmental conditions.
![Research image of oligodendrocytes in mice treated with clemastine compared to untreated mice.](https://www.thetransmitter.org/wp-content/uploads/2023/05/844-lede-demo-1.png)
Antihistamine aids myelination in Pitt-Hopkins mice
The drug clemastine and other compounds that fortify the protective sheath around neurons may prove therapeutic for some genetic neurodevelopmental conditions.
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Temperature tunes circadian timing in some desert mammals
Light has hogged all the attention in chronobiology research—but now, in camel, goat and mole rat experiments, temperature takes the lead.
![A man walks a dromedary camel down a hallway.](https://www.thetransmitter.org/wp-content/uploads/2024/06/camel-walking-1200-1024x692.webp)
Temperature tunes circadian timing in some desert mammals
Light has hogged all the attention in chronobiology research—but now, in camel, goat and mole rat experiments, temperature takes the lead.
Synaptic anomalies in autistic people support imbalance hypothesis
Increased excitatory and decreased inhibitory synapses in the prefrontal cortex of autistic people suggest broader impacts on brain function and connectivity.
![Research image of excitatory synapses in the prefrontal cortex.](https://www.thetransmitter.org/wp-content/uploads/2024/06/Fig2BD3BD-1200-1024x692.webp)
Synaptic anomalies in autistic people support imbalance hypothesis
Increased excitatory and decreased inhibitory synapses in the prefrontal cortex of autistic people suggest broader impacts on brain function and connectivity.
Opioid receptors may guide formation of gut nervous system in zebrafish
Fish lacking functional copies of the receptors have fewer enteric neurons than usual, but the findings await further validation.
![Research image of enteric neurons in zebrafish.](https://www.thetransmitter.org/wp-content/uploads/2024/06/Fig2D-fish-1200-1024x692.webp)
Opioid receptors may guide formation of gut nervous system in zebrafish
Fish lacking functional copies of the receptors have fewer enteric neurons than usual, but the findings await further validation.