Mouse models

Recent articles

Illustration of a shrew, sandpiper, locust, axolotl, monarch butterfly, African killifish, naked mole rat, octopus, bat and cichlid.

The non-model organism “renaissance” has arrived

Meet 10 neuroscientists bringing model diversity back with the funky animals they study.

Expanding set of viral tools targets almost any brain cell type

Harmless viruses that encase short noncoding DNA elements called enhancers enable cell-type-specific gene delivery across the central nervous system in rodents and primates.

By Holly Barker
19 November 2024 | 2 min watch
Research image of a portion of mouse brain.

Stress warps fear memories in multiple ways

Expanding the bounds of a fear memory or linking it to a neutral memory can shape a mouse’s fear response, two new studies show.

By Claudia López Lloreda
15 November 2024 | 5 min read
Research image of astrocytes in red activating alongside neurons in green in response to specific fear memories in mice.

Astrocytes star in memory storage, recall

The cells, long cast as support players in memory research, can activate or disrupt fear memories, according to a new study.

By Angie Voyles Askham
6 November 2024 | 5 min read
Two mice fighting.

Synaptic changes shape winning mice into bullies

When a mouse repeatedly defeats its opponents, brain circuits that underlie aggressive behaviors develop more stable connections, helping to ensure continual triumph, a new study shows.

By Claudia López Lloreda
14 October 2024 | 6 min read
Research image of neurons in the nucleus of the mouse solitary tract.

Cell population in brainstem coordinates cough, new study shows

The work also adds to a growing body of evidence showing that mice, and their genetic toolbox, can be used to study cough.

By Calli McMurray
6 September 2024 | 5 min read
Illustration of ketamine blocking open ion channels in active NMDA receptors, quieting the cells and disrupting downstream signaling involved in depression.

Ketamine targets lateral habenula, setting off cascade of antidepressant effects

The drug’s affinity for overactive cells in the “anti-reward” region may help explain its rapid and long-lasting results.

By Olivia Gieger
4 September 2024 | 6 min read
Illustrated portrait of Lin Tian.

Biosensors and being fearless with Lin Tian

Tian discusses protein function and structure, and the historic city in China where she was born.

By Brady Huggett
1 September 2024 | 62 min listen
Research image of fetal macaque brains.

Brain patterning in utero may be implicated in autism, other conditions

Genes tied to several conditions are expressed in regions that control neural stem cell fate within the first few months post-conception.

By Chloe Williams
1 August 2024 | 6 min read
Research image of neurons in the rostral anterior cingulate cortex (right, in green) sending signals to cells in the pontine nucleus (left, in yellow) to quell pain.

Cerebellar circuit may convert expected pain relief into real thing

The newly identified circuit taps into the brain’s opioid system to provide a top-down form of pain relief.

By Angie Voyles Askham
24 July 2024 | 6 min read

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The Transmitter’s favorite essays and columns of 2024

From sex differences in Alzheimer’s disease to enduring citation bias, experts weighed in on important scientific and practical issues in neuroscience.

By The Transmitter
23 December 2024 | 2 min read
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Say what? The Transmitter’s top quotes of 2024

“We’ve cured mouse-heimer’s thousands of times...”—find out who said this to a Transmitter reporter, and read our other favorite quotes from the past year.

By The Transmitter
23 December 2024 | 2 min read
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The Transmitter’s favorite podcasts of 2024

Our picks include a deep dive into dopamine, the role of PKMzeta in memory, and studying the stomatogastric ganglion.

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