Mouse models
Recent articles
Cell population in brainstem coordinates cough, new study shows
The work also adds to a growing body of evidence showing that mice, and their genetic toolbox, can be used to study cough.
![](https://www.thetransmitter.org/wp-content/uploads/2024/09/1200_coughingmice-1024x720.webp)
Cell population in brainstem coordinates cough, new study shows
The work also adds to a growing body of evidence showing that mice, and their genetic toolbox, can be used to study cough.
Ketamine targets lateral habenula, setting off cascade of antidepressant effects
The drug’s affinity for overactive cells in the “anti-reward” region may help explain its rapid and long-lasting results.
![Illustration of ketamine blocking open ion channels in active NMDA receptors, quieting the cells and disrupting downstream signaling involved in depression.](https://www.thetransmitter.org/wp-content/uploads/2024/09/1200-ketamine-receptor-transmitter-neuroscience-1024x683.webp)
Ketamine targets lateral habenula, setting off cascade of antidepressant effects
The drug’s affinity for overactive cells in the “anti-reward” region may help explain its rapid and long-lasting results.
Biosensors and being fearless with Lin Tian
Tian discusses protein function and structure, and the historic city in China where she was born.
![Illustrated portrait of Lin Tian.](https://www.thetransmitter.org/wp-content/uploads/2024/08/lin-tian-synaptic-1200-1024x683.webp)
Biosensors and being fearless with Lin Tian
Tian discusses protein function and structure, and the historic city in China where she was born.
Brain patterning in utero may be implicated in autism, other conditions
Genes tied to several conditions are expressed in regions that control neural stem cell fate within the first few months post-conception.
![Research image of fetal macaque brains.](https://www.thetransmitter.org/wp-content/uploads/2024/08/lede-patterning-1200-1024x692.webp)
Brain patterning in utero may be implicated in autism, other conditions
Genes tied to several conditions are expressed in regions that control neural stem cell fate within the first few months post-conception.
Cerebellar circuit may convert expected pain relief into real thing
The newly identified circuit taps into the brain’s opioid system to provide a top-down form of pain relief.
![Research image of neurons in the rostral anterior cingulate cortex (right, in green) sending signals to cells in the pontine nucleus (left, in yellow) to quell pain.](https://www.thetransmitter.org/wp-content/uploads/2024/07/paincircuit-1200-1024x692.webp)
Cerebellar circuit may convert expected pain relief into real thing
The newly identified circuit taps into the brain’s opioid system to provide a top-down form of pain relief.
Widely used calcium imaging protocol can lead to spurious results, new paper cautions
The technique, which measures calcium currents as a proxy for neuronal firing, sometimes reports unusual and potentially misleading waves of activity in the hippocampus.
Widely used calcium imaging protocol can lead to spurious results, new paper cautions
The technique, which measures calcium currents as a proxy for neuronal firing, sometimes reports unusual and potentially misleading waves of activity in the hippocampus.
Connectivity takes U-turn in people with rare autism-linked mutations
Patterns of brain connectivity shift during puberty in people with deletion of the 22q11.2 chromosomal region.
![Research image of brain activity](https://www.thetransmitter.org/wp-content/uploads/2024/05/1200_connectivity-1024x683.png)
Connectivity takes U-turn in people with rare autism-linked mutations
Patterns of brain connectivity shift during puberty in people with deletion of the 22q11.2 chromosomal region.
Cocaine, morphine commandeer neurons normally activated by food, water in mice
Confirming a long-held hypothesis, repeated exposure to the drugs alters neurons in the nucleus accumbens, the brain’s reward center, and curbs an animal’s urge for sustenance.
![A diagram of green neurnons](https://www.thetransmitter.org/wp-content/uploads/2024/05/Green-neuron-art-1200-1024x692.webp)
Cocaine, morphine commandeer neurons normally activated by food, water in mice
Confirming a long-held hypothesis, repeated exposure to the drugs alters neurons in the nucleus accumbens, the brain’s reward center, and curbs an animal’s urge for sustenance.
‘It must be something I ate’ is hard-wired into the brain
Feeling sick reactivates “novel flavor” neurons, according to a new study in mice, and points to a dedicated circuit for learning to avoid unsafe food.
![Computer-generated illustration of disgusting green food.](https://www.thetransmitter.org/wp-content/uploads/2024/03/1200-transmitter-neuroscience-food-aversion-1024x692.webp)
‘It must be something I ate’ is hard-wired into the brain
Feeling sick reactivates “novel flavor” neurons, according to a new study in mice, and points to a dedicated circuit for learning to avoid unsafe food.
Microglial overreaction to atypical neurons may drive autism
In mice and organoids lacking a neuronal protein, microglia prune synapses to excess.
![Research image of microglia in mice.](https://www.thetransmitter.org/wp-content/uploads/2023/12/1200-microglia-pruning-transmitter-neuroscience-1024x683.webp)
Microglial overreaction to atypical neurons may drive autism
In mice and organoids lacking a neuronal protein, microglia prune synapses to excess.
Explore more from The Transmitter
In updated U.S. autism bill, Congress calls for funding boost, expanded scope
The current Autism CARES Act sunsets in late September.
![Capitol building](https://www.thetransmitter.org/wp-content/uploads/2024/09/capitolhill-1200-1024x692.webp)
In updated U.S. autism bill, Congress calls for funding boost, expanded scope
The current Autism CARES Act sunsets in late September.
X-chromosome genes; neurobiology of infant crying; MCHAT in preemies
Here is a roundup of autism-related news and research spotted around the web for the week of 2 September.
![Research image of astrocytes and microglia in mouse brains.](https://www.thetransmitter.org/wp-content/uploads/2024/08/1200-spotted-20240903-1024x683.webp)
X-chromosome genes; neurobiology of infant crying; MCHAT in preemies
Here is a roundup of autism-related news and research spotted around the web for the week of 2 September.
From bench to bot: Does AI really make you a more efficient writer?
A more significant benefit may lie in improving quality, refining tone and reducing cognitive burden. But beware of bias.
![Computer-generated illustration of a pencil.](https://www.thetransmitter.org/wp-content/uploads/2024/08/APpencil-1200-1024x692.webp)
From bench to bot: Does AI really make you a more efficient writer?
A more significant benefit may lie in improving quality, refining tone and reducing cognitive burden. But beware of bias.