Mouse models
Recent articles
Molecular changes after MECP2 loss may drive Rett syndrome traits
Knocking out the gene in adult mice triggered up- and down-regulated expression of myriad genes weeks before there were changes in neuronal function.
Molecular changes after MECP2 loss may drive Rett syndrome traits
Knocking out the gene in adult mice triggered up- and down-regulated expression of myriad genes weeks before there were changes in neuronal function.
Targeting NMDA receptor subunit reverses fragile X traits in mice
The subunit acts as a “volume control” on signaling that shapes the density of dendritic spines, the new work suggests.
Targeting NMDA receptor subunit reverses fragile X traits in mice
The subunit acts as a “volume control” on signaling that shapes the density of dendritic spines, the new work suggests.
Soft touch quells loneliness in mice
Touch modulates one of two dueling types of hypothalamic neurons that, thermostat-like, balance an animal’s drive for social interaction.
Soft touch quells loneliness in mice
Touch modulates one of two dueling types of hypothalamic neurons that, thermostat-like, balance an animal’s drive for social interaction.
X marks the spot in search for autism variants
Genetic variants on the X chromosome, including those in the gene DDX53, contribute to autism’s gender imbalance, two new studies suggest.
X marks the spot in search for autism variants
Genetic variants on the X chromosome, including those in the gene DDX53, contribute to autism’s gender imbalance, two new studies suggest.
The non-model organism “renaissance” has arrived
Meet 10 neuroscientists bringing model diversity back with the funky animals they study.
The non-model organism “renaissance” has arrived
Meet 10 neuroscientists bringing model diversity back with the funky animals they study.
Expanding set of viral tools targets almost any brain cell type
Harmless viruses that encase short noncoding DNA elements called enhancers enable cell-type-specific gene delivery across the central nervous system in rodents and primates.
Expanding set of viral tools targets almost any brain cell type
Harmless viruses that encase short noncoding DNA elements called enhancers enable cell-type-specific gene delivery across the central nervous system in rodents and primates.
Stress warps fear memories in multiple ways
Expanding the bounds of a fear memory or linking it to a neutral memory can shape a mouse’s fear response, two new studies show.
Stress warps fear memories in multiple ways
Expanding the bounds of a fear memory or linking it to a neutral memory can shape a mouse’s fear response, two new studies show.
Astrocytes star in memory storage, recall
The cells, long cast as support players in memory research, can activate or disrupt fear memories, according to a new study.
Astrocytes star in memory storage, recall
The cells, long cast as support players in memory research, can activate or disrupt fear memories, according to a new study.
Synaptic changes shape winning mice into bullies
When a mouse repeatedly defeats its opponents, brain circuits that underlie aggressive behaviors develop more stable connections, helping to ensure continual triumph, a new study shows.
Synaptic changes shape winning mice into bullies
When a mouse repeatedly defeats its opponents, brain circuits that underlie aggressive behaviors develop more stable connections, helping to ensure continual triumph, a new study shows.
Cell population in brainstem coordinates cough, new study shows
The work also adds to a growing body of evidence showing that mice, and their genetic toolbox, can be used to study cough.
Cell population in brainstem coordinates cough, new study shows
The work also adds to a growing body of evidence showing that mice, and their genetic toolbox, can be used to study cough.
Explore more from The Transmitter
Acting NIH director dismisses four neuroscientists from advisory boards
The letters they received this week did not include a reason for their termination.
Acting NIH director dismisses four neuroscientists from advisory boards
The letters they received this week did not include a reason for their termination.
NIH neurodevelopmental assessment system now available as iPad app
Here is a roundup of autism-related news and research spotted around the web for the week of 24 March.
NIH neurodevelopmental assessment system now available as iPad app
Here is a roundup of autism-related news and research spotted around the web for the week of 24 March.
Keep sex as a biological variable: Don’t let NIH upheaval turn back the clock on scientific rigor
Even in the absence of any formal instruction to do so, we should continue to hold our ourselves and our neuroscience colleagues accountable for SABV practices.
Keep sex as a biological variable: Don’t let NIH upheaval turn back the clock on scientific rigor
Even in the absence of any formal instruction to do so, we should continue to hold our ourselves and our neuroscience colleagues accountable for SABV practices.