Microscopy

Recent articles

Research image of simultaneous imaging of neurons.

Optimized two-photon microscopy enables voltage imaging at multiple depths

The tool could reveal how information flows within and between cortical layers during neural processing.

By Simon Makin
11 August 2026 | 4 min read

A planetarium for the brain

Tyler Sloan’s new film, more than a decade in the making, takes viewers on an immersive journey.

By Emily Singer
27 July 2026 | 1 min watch
Adam Kampff.

Remembering Adam Kampff, neuroscience educator and researcher

Kampff’s do-it-yourself approach inspired a generation of neuroscientists.

By Lauren Schneider
24 December 2025 | 6 min read
Research image of a mouse brain with the same spot shown three times in different colors to show different neurochemical concentrations.

New dopamine sensor powers three-color imaging in live animals

The tool leverages a previously unused segment of the color spectrum to track the neurotransmitter and can be used with two additional sensors to monitor other neurochemicals at different wavelengths.

By Diana Kwon
25 July 2025 | 4 min read
Detailed image of neurons in the mouse visual cortex.

Inhibitory cells work in concert to orchestrate neuronal activity in mouse brain

A cubic millimeter of brain tissue, meticulously sectioned, stained and scrutinized over the past seven years, reveals in stunning detail the role of inhibitory interneurons in brain structure and function.

By Katie Moisse
9 April 2025 | 6 min read
Astrocytes in a mouse brain.

Unexpected astrocyte gene flips image of brain’s ‘stalwart sentinels’

The genetic marker upends the accepted orientation of non-star-like astrocytes in the glia limitans superficialis.

By Lauren Schenkman
28 March 2025 | 5 min read

New tissue-clearing techniques let microscopes peer deeper into living brains

Washing mouse brain tissue with a blood protein or complex sugar can illuminate cells 550 micrometers into the cortex without compromising its normal physiology.

By Calli McMurray
18 October 2024 | 0 min watch

Octopus arm anatomy, molecular makeup revealed in new maps

The datasets provide “a very nice reference” for future functional studies.

By Calli McMurray
25 September 2024 | 1 min watch
A dense reconstruction of layer 2/3 neurons of the mouse visual cortex containing 394 neurons and 3.2 million synapses.

To develop better nervous-system visualizations, we need to think BIG

With a full mouse connectome on the horizon, neuroscience needs to overcome its legacy of minimalism and embrace the contemporary challenge of representing whole-nervous-system connectivity.

By Tyler Sloan
8 July 2024 | 8 min read
Image of neural activity in a mouse as seen through the Miniscope.

Designing an open-source microscope

Funding for the development of open-source tools is on the rise, but support for their maintenance and dissemination, both crucial for their meaningful uptake, remains a major challenge.

By Daniel Aharoni
17 June 2024 | 6 min read

Explore more from The Transmitter

How energy determines where proteins are produced in neurons

Tatjana Tchumatchenko explains how mathematical modeling elucidates whether ion-channel proteins are produced locally in the soma or in the dendrites.

By Gaute Einevoll
26 August 2026 | 1 min read
A brown mouse between a red cube and blue cylinder looks curiously at the top of the cylinder, standing on hind legs.

Wouldn’t you like to know? A mouse would

Mice seek information for curiosity’s sake—and their desire for knowledge versus a payout is represented distinctly in the brain, new findings suggest.

By Sarah Thau
26 August 2026 | 5 min read
Covers of The Transmitter's summer book picks.

Five new neuroscience books, and other notable titles from 2026

The Transmitter’s summer reading list includes an autopsy of the Human Brain Project, an overview of the neuroscience of motherhood and a memoir from a pioneer in Huntington’s disease research.

By Francisco J. Rivera Rosario
25 August 2026 | 7 min read