Methylation

Recent articles

Unknown isoform adds twist to theory of fragile X origins

Contrary to conventional wisdom, most people with fragile X syndrome express the FMR1 gene — albeit improperly.

By Holly Barker
11 July 2023 | 6 min read
Illustration of a fragile X syndrome chromosome.

New gene-editing method flags fragile X mutation for repair

The approach prompts cultured cells to correct the genetic mutation in fragile X syndrome using their own DNA repair system, but it still needs to be tested further.

By Angie Voyles Askham
5 July 2023 | 6 min listen

Explore more from The Transmitter

Coding error caused layoffs at National Institute of Neurological Disorders and Stroke this week, source says

Thirty employees—including 11 lab heads—at the institute should “immediately return to work,” according to an email the institute’s Office of Human Resources sent to top administration at the institute Wednesday evening.

By Sydney Wyatt
3 April 2025 | 3 min read

PTEN problems underscore autism connection to excess brain fluid

Damaging variants in the autism-linked gene cause congenital hydrocephalus—a buildup of cerebrospinal fluid in the brain—by turbocharging a downstream signaling pathway that promotes the growth of cells, according to a new study.

By Holly Barker
3 April 2025 | 4 min read

U.S. health agency purge includes 10 lab heads at National Institute of Neurological Disorders and Stroke

The reasons for selecting these researchers—who have led work on neuronal migration, dopamine receptors in neuronal signaling and the structure of ion channels, among other areas—remain unclear.

By Angie Voyles Askham, Sydney Wyatt
2 April 2025 | 5 min read