Methylation

Recent articles

Unknown isoform adds twist to theory of fragile X origins

Contrary to conventional wisdom, most people with fragile X syndrome express the FMR1 gene — albeit improperly.

By Holly Barker
11 July 2023 | 6 min read
Illustration of a fragile X syndrome chromosome.

New gene-editing method flags fragile X mutation for repair

The approach prompts cultured cells to correct the genetic mutation in fragile X syndrome using their own DNA repair system, but it still needs to be tested further.

By Angie Voyles Askham
5 July 2023 | 5 min read

Explore more from The Transmitter

Home makeover helps rats better express themselves: Q&A with Raven Hickson and Peter Kind

The “Habitat”—a complex environment with space for large social groups—expands the behavioral repertoire of rodent models, Hickson and Kind say.

By Holly Barker
4 December 2025 | 0 min watch

Tatiana Engel explains how to connect high-dimensional neural circuitry with low-dimensional cognitive functions

Neuroscientists have long sought to understand the relationship between structure and function in the vast connectivity and activity patterns in the brain. Engel discusses her modeling approach to discovering the hidden patterns that connect the two.

By Paul Middlebrooks
3 December 2025 | 1 min read
A hand holds a clear rectangular prism up to a series of abstract patterns, offering a new view of them.

Beyond the algorithmic oracle: Rethinking machine learning in behavioral neuroscience

Machine learning should not be a replacement for human judgment but rather help us embrace the various assumptions and interpretations that shape behavioral research.

By Nedah Nemati, Matthew Whiteway
3 December 2025 | 7 min read

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