Memory
Recent articles
To persist, memories surf molecular waves from thalamus to cortex
During the later stages of learning, the mouse brain progressively activates transcriptional regulators that drive memory consolidation.
To persist, memories surf molecular waves from thalamus to cortex
During the later stages of learning, the mouse brain progressively activates transcriptional regulators that drive memory consolidation.
Gene replacement therapy normalizes some traits in SYNGAP1 model mice
The first published virus-based gene therapy for SYNGAP1 deletion yields benefits despite the gene’s long length and complexity.
Gene replacement therapy normalizes some traits in SYNGAP1 model mice
The first published virus-based gene therapy for SYNGAP1 deletion yields benefits despite the gene’s long length and complexity.
‘How to Change a Memory: One Neuroscientist’s Quest to Alter the Past,’ an excerpt
Part scientific exploration, part memoir, Steve Ramirez’s new book delves into the study of memory manipulation and his personal journey of discovery, friendship and grief.
‘How to Change a Memory: One Neuroscientist’s Quest to Alter the Past,’ an excerpt
Part scientific exploration, part memoir, Steve Ramirez’s new book delves into the study of memory manipulation and his personal journey of discovery, friendship and grief.
Engrams in amygdala lean on astrocytes to solidify memories
Disrupting the astrocyte-neuronal dynamic in mice destabilizes their memory of fear conditioning.
Engrams in amygdala lean on astrocytes to solidify memories
Disrupting the astrocyte-neuronal dynamic in mice destabilizes their memory of fear conditioning.
Paper by memory institute director garners expression of concern over image integrity
The notice, posted last week in Nature, follows a recent string of corrections to at least three other articles by Li-Huei Tsai’s lab.
Paper by memory institute director garners expression of concern over image integrity
The notice, posted last week in Nature, follows a recent string of corrections to at least three other articles by Li-Huei Tsai’s lab.
Emotion research has a communication conundrum
In 2025, the words we use to describe emotions matter, but their definitions are controversial. Here, I unpack the different positions in this space and the rationales behind them—and I invite 13 experts to chime in.
Emotion research has a communication conundrum
In 2025, the words we use to describe emotions matter, but their definitions are controversial. Here, I unpack the different positions in this space and the rationales behind them—and I invite 13 experts to chime in.
The Transmitter’s reading list: Six upcoming neuroscience books, plus notable titles in 2025
Dig into an exploration of the fundamental aspects of intelligence, a new textbook about theoretical neuroscience and a memoir about memory research, among other new releases.
The Transmitter’s reading list: Six upcoming neuroscience books, plus notable titles in 2025
Dig into an exploration of the fundamental aspects of intelligence, a new textbook about theoretical neuroscience and a memoir about memory research, among other new releases.
Memory study sparks debate over statistical methods
Critics of a 2024 Nature paper suggest the authors failed to address the risk of false-positive findings. The authors argue more rigorous methods can result in missed leads.
Memory study sparks debate over statistical methods
Critics of a 2024 Nature paper suggest the authors failed to address the risk of false-positive findings. The authors argue more rigorous methods can result in missed leads.
Expanded view of hippocampal function comes into focus
After decades of debate, the region’s role is being rewritten. Rather than using sensory input to simply log key points in time and space, the hippocampus may serve to contextualize our experiences and memories—and ultimately make predictions about the future.
Expanded view of hippocampal function comes into focus
After decades of debate, the region’s role is being rewritten. Rather than using sensory input to simply log key points in time and space, the hippocampus may serve to contextualize our experiences and memories—and ultimately make predictions about the future.
Learning in living mice defies classic synaptic plasticity rule
Donald Hebb’s theory—memorably summarized as “cells that fire together, wire together”—does not explain the shifting hippocampal connections in mice learning to navigate a virtual environment, according to a new study.
Learning in living mice defies classic synaptic plasticity rule
Donald Hebb’s theory—memorably summarized as “cells that fire together, wire together”—does not explain the shifting hippocampal connections in mice learning to navigate a virtual environment, according to a new study.
Explore more from The Transmitter
Psilocybin rewires specific mouse cortical networks in lasting ways
Neuronal activity induced by the psychedelic drug strengthens inputs from sensory brain areas and weakens cortico-cortical recurrent loops.
Psilocybin rewires specific mouse cortical networks in lasting ways
Neuronal activity induced by the psychedelic drug strengthens inputs from sensory brain areas and weakens cortico-cortical recurrent loops.
Home makeover helps rats better express themselves: Q&A with Raven Hickson and Peter Kind
The “Habitat”—a complex environment with space for large social groups—expands the behavioral repertoire of rodent models, Hickson and Kind say.
Home makeover helps rats better express themselves: Q&A with Raven Hickson and Peter Kind
The “Habitat”—a complex environment with space for large social groups—expands the behavioral repertoire of rodent models, Hickson and Kind say.
Tatiana Engel explains how to connect high-dimensional neural circuitry with low-dimensional cognitive functions
Neuroscientists have long sought to understand the relationship between structure and function in the vast connectivity and activity patterns in the brain. Engel discusses her modeling approach to discovering the hidden patterns that connect the two.
Tatiana Engel explains how to connect high-dimensional neural circuitry with low-dimensional cognitive functions
Neuroscientists have long sought to understand the relationship between structure and function in the vast connectivity and activity patterns in the brain. Engel discusses her modeling approach to discovering the hidden patterns that connect the two.