Manifolds

Recent articles

Tatiana Engel explains how to connect high-dimensional neural circuitry with low-dimensional cognitive functions

Neuroscientists have long sought to understand the relationship between structure and function in the vast connectivity and activity patterns in the brain. Engel discusses her modeling approach to discovering the hidden patterns that connect the two.

By Paul Middlebrooks
3 December 2025 | 1 min read
Illustration of a colorful, donut-shaped object resting on a distorted plane with its own topography.

Neural manifolds: Latest buzzword or pathway to understand the brain?

When you cut away the misconceptions, neural manifolds present a conceptually appropriate level at which systems neuroscientists can study the brain.

By Matthew Perich
2 October 2024 | 8 min read

Explore more from The Transmitter

Clockwise: lab mouse, zebrafish, octopus, rat pushing a cube, nematodes, fruit fly.

The term ‘model organism’ should be reserved for biological systems

By referring to artificial neural networks as model organisms, we run the risk of distorting funding priorities and disregard the explanatory power of a shared evolutionary history across biological organisms.

By Marc Coutanche
13 November 2026 | 6 min read

New phase of BRAIN Initiative spawns basal ganglia ‘parts list’

With a standardized cell naming system and infrastructure for data collection and analysis, the basal ganglia project sets the stage for a whole-brain primate atlas.

By Claudia López Lloreda
12 November 2026 | 1 min watch
Research image showing genes containing microexons in mice.

Machine-learning model spots autism-linked variants that scramble splicing

The model provides a way to investigate genetic variation in regions of the genome whose functions have been difficult to interpret.

By Giorgia Guglielmi
12 November 2026 | 4 min read