Manifolds

Recent articles

Tatiana Engel explains how to connect high-dimensional neural circuitry with low-dimensional cognitive functions

Neuroscientists have long sought to understand the relationship between structure and function in the vast connectivity and activity patterns in the brain. Engel discusses her modeling approach to discovering the hidden patterns that connect the two.

By Paul Middlebrooks
3 December 2025 | 1 min read
Illustration of a colorful, donut-shaped object resting on a distorted plane with its own topography.

Neural manifolds: Latest buzzword or pathway to understand the brain?

When you cut away the misconceptions, neural manifolds present a conceptually appropriate level at which systems neuroscientists can study the brain.

By Matthew Perich
2 October 2024 | 8 min read

Explore more from The Transmitter

Research image of the mouse dentate gyrus.

Microglia implicated in infantile amnesia

The glial cells could explain the link between maternal immune activation and autism-like behaviors in mice, but methodological challenges prompt questions about the new evidence.

By Lauren Schneider
12 February 2026 | 5 min read
Research image of myelinated axons.

Oligodendrocytes need mechanical cues to myelinate axons correctly

Without the mechanosensor TMEM63A, the cells cannot deposit the appropriate amount of insulation, according to a new study.

By Calli McMurray
11 February 2026 | 5 min read

Modern AI is simply no match for the complexity likely required for harboring consciousness, says Jaan Aru

He argues that our brain’s computations are of a completely different nature than any artificial intelligence because they take place across many spatial and temporal scales and are inextricably entwined with biological materials.

By Paul Middlebrooks
11 February 2026 | 1 min read

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