Manifolds

Recent articles

Tatiana Engel explains how to connect high-dimensional neural circuitry with low-dimensional cognitive functions

Neuroscientists have long sought to understand the relationship between structure and function in the vast connectivity and activity patterns in the brain. Engel discusses her modeling approach to discovering the hidden patterns that connect the two.

By Paul Middlebrooks
3 December 2025 | 1 min read
Illustration of a colorful, donut-shaped object resting on a distorted plane with its own topography.

Neural manifolds: Latest buzzword or pathway to understand the brain?

When you cut away the misconceptions, neural manifolds present a conceptually appropriate level at which systems neuroscientists can study the brain.

By Matthew Perich
2 October 2024 | 8 min read

Explore more from The Transmitter

Nearly 400 compounds affect behaviors tied to autism-linked genes in zebrafish

Estropipate, paclitaxel and levocarnitine altered behaviors tied to SCN2A and DYRK1A variants specifically, a new open-source platform revealed.

By Charles Q. Choi
16 April 2026 | 4 min read

What neuroscientists want from a new NINDS director

The search is underway for the next director of the U.S. National Institute of Neurological Disorders and Stroke, who will face a range of challenges, neuroscientists say, but will also have an “immense opportunity to do good things.”

By Helena Kudiabor
15 April 2026 | 4 min read
3D illustration of arterial blood supply in the human brain.

Arousal neurons’ activity explains brain’s blood flow dynamics in mice

The findings could influence how researchers interpret signals from techniques that use blood flow as a surrogate for neuronal activity.

By Claudia López Lloreda
15 April 2026 | 5 min read