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Learn about early-career scientists starting their own labs.

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Interviews have been lightly edited for length and clarity.

December 2025

Alexandra Decker, assistant professor of psychological and brain sciences, Washington University in St. Louis

Lab start date: January 2026

What do you study? What part of your research are you most excited about?

Brains are dynamic systems, constantly shifting and adapting from one moment to the next. My lab asks how these fluctuations shape attention, learning and memory—and what this variability reveals about the principles that make our brains so flexible and adaptive. I’m excited that I get to keep learning and exploring the idea that variability in cognition isn’t a “bug” but a hallmark of an adaptive system designed to balance competing needs, such as exploration and focus; learning and predicting; and stability and flexibility.

Are there any traditions or practices from the labs you trained in that you will implement in your own lab?

In my previous lab, we had a “big, crazy ideas” lab meeting, where everyone pitched bold ideas with no data. I’m adopting that—and adding a brief “anything‑cool‑I‑learned‑this‑week” round before each lab meeting, where we share something new we learned that week, such as why puffins and penguins look similar but aren’t related or how chess champions strategize.

What is the best advice you received from a mentor or colleague before opening your lab?

One of my colleagues is always reminding me to “just relax, because nothing is under control.” This idea first made me laugh and then terrified me, but now I have it pasted as a sticker on my laptop. Remembering that much of success and failure is outside my control frees me to focus on learning, doing my best, having empathy and not worrying too much about the outcome.

Hannah Shoenhard, assistant professor of biology, Bryn Mawr College

Lab start date: January 2025

What do you study? What part of your research are you most excited about?

Missing sleep can interfere with the ability to consolidate long-term memories, not just in humans but in many different animals across many different memory paradigms. My lab is using genetic and behavioral methods in fruit flies to compare two forms of memory: one that is consolidated during sleep and one that doesn’t require sleep to consolidate. We hope to discover how cellular and metabolic strategies for memory consolidation are deployed differently in sleep versus awake states. This research might even one day point toward strategies for supporting memory, even in people who get poor sleep.

Over the summer, one of my students replicated an odd incidental finding that I had made during my postdoc. It was one of those things that didn’t really answer the question I was asking at the time, so I set it aside. But now that I’m a PI, I’m excited to develop that into its own story. It’s early days yet, and we still have a ton of work to do to validate the initial finding, but if it pans out, it’s going to be really cool.

What is the best advice you received from a mentor or colleague before opening your lab?

Order Drosophila incubators at least 120 days in advance, and make sure you have a 20-amp outlet to plug them into!

Actually, though, the best “advice” I got was more of an attitude. Another postdoc from the Sehgal Lab, where I trained, and who got a faculty position, received a going-away present of a flint and steel. The joke was that when you start your own lab, you’re setting up from scratch—it’s on you to get the metaphorical fires burning. At the same time, it’s a gentle reminder not to expect as much of your science productivity in the first couple of “flint and steel” years. In an established lab, it’s easy to take for granted not just the equipment but also the troubleshooting expertise, the lab culture and the network of intellectual and emotional support that surrounds you. It takes time to build that technology back up.

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