Hippocampus

Recent articles

Eleanor Maguire.

Remembering Eleanor Maguire, ‘trailblazer’ of human memory

Maguire, mastermind of the famous London taxi-driver study, broadened the field and championed the importance of spatial representations in memory.

By Calli McMurray
10 January 2025 | 8 min read
Four microphones on a table with speech bubbles above them.

The Transmitter’s favorite podcasts of 2024

Our picks include a deep dive into dopamine, the role of PKMzeta in memory, and studying the stomatogastric ganglion.

By The Transmitter
23 December 2024 | 1 min read
Research image of astrocytes in red activating alongside neurons in green in response to specific fear memories in mice.

Astrocytes star in memory storage, recall

The cells, long cast as support players in memory research, can activate or disrupt fear memories, according to a new study.

By Angie Voyles Askham
6 November 2024 | 5 min read
Photograph of two hands drawing overlapping red and blue waveforms on a chalkboard.

How to teach this paper: ‘Coordination of entorhinal-hippocampal ensemble activity during associative learning,’ by Igarashi et al. (2014)

Kei Igarashi and his colleagues established an important foundation in memory research: the premise that brain regions oscillate together to form synaptic connections and, ultimately, memories.

By Ashley Juavinett
4 November 2024 | 8 min read
Illustration of a brain.

This paper changed my life: ‘Response of hippocampal synapses to natural stimulation patterns,’ by Dobrunz and Stevens

The work demonstrated how to effectively combine controlled in-vitro experiments and the messiness of natural brain patterns.

By Robert Froemke
17 September 2024 | 4 min read
Illustration of ketamine blocking open ion channels in active NMDA receptors, quieting the cells and disrupting downstream signaling involved in depression.

Ketamine targets lateral habenula, setting off cascade of antidepressant effects

The drug’s affinity for overactive cells in the “anti-reward” region may help explain its rapid and long-lasting results.

By Olivia Gieger
4 September 2024 | 6 min read
Research image of place cells plotted onto a reference zebrafish larva brain.

‘Place cells’ help guide freely swimming zebrafish larvae

The newly found cells function like those in mammals, revealing that spatial cognition evolved earlier than previously thought.

By Shaena Montanari
28 August 2024 | 5 min read
Illustration of a group of books floating against a light blue and yellow background.

Six new neuroscience books for fall—plus five titles you may have missed

We highlight the most anticipated neuroscience books for the remainder of 2024 and recap notable releases since last December.

By Francisco J. Rivera Rosario
26 August 2024 | 6 min read
Illustration of a neuron with cardinal directions superimposed over it as on a compass.

Neurons’ spikes may convey their whereabouts

The time lag between spurts of activity holds anatomical information, according to a preprint.

By Holly Barker
23 August 2024 | 4 min read
Research image of tau proteins in the brains of people with Alzheimer’s disease.

Supersized version of Alzheimer’s protein avoids clumping in brain

“Big tau” may explain why some brain regions, such as the cerebellum and brainstem, are largely spared from neurodegeneration, even though tau is expressed throughout the nervous system.

By Charles Q. Choi
16 August 2024 | 6 min read

Explore more from The Transmitter

Colorful illustration of a latticework of proteins.

Cracking the code of the extracellular matrix

Despite evidence for a role in plasticity and other crucial functions, many neuroscientists still view these proteins as “brain goop.” The field needs technical advances and a shift in scientific thinking to move beyond this outdated perspective.

By Anna Victoria Molofsky
17 January 2025 | 5 min read
A repeated DNA strand extends farther from the left side of the image with each iteration.

Huntington’s disease gene variants past a certain size poison select cells

The findings—providing “the next step in the whole pathway”—help explain the disease’s late onset and offer hope that it has an extended therapeutic window.

By Angie Voyles Askham
16 January 2025 | 6 min read
Research image highlighting different brain regions.

X marks the spot in search for autism variants

Genetic variants on the X chromosome, including those in the gene DDX53, contribute to autism’s gender imbalance, two new studies suggest.

By Holly Barker
16 January 2025 | 6 min read