GWAS

Recent articles

A younger looking set of hands holds an older looking set of hands.

New catalog charts familial ties from autism to 90 other conditions

The research tool reveals associations stretching across three generations.

By Charles Q. Choi
17 October 2024 | 4 min read
Illustration of a brain made up of many smaller brains.

Breaking down the winner’s curse: Lessons from brain-wide association studies

We found an issue with a specific type of brain imaging study and tried to share it with the field. Then the backlash began.

By Nico Dosenbach, Scott Marek
25 March 2024 | 7 min listen

Common genetic variants shape the structure of the cortex

A genome-wide association study lays a foundation for deeper investigation of these variants in neurodevelopmental conditions.

By Lauren Schenkman
18 September 2023 | 6 min listen
Research diagram of gene clusters.

Atlas of gene activity in prenatal brain holds clues to autism

Genes exert their strongest influence on the brain in the first half of gestation — a key window for autism and other neurodevelopmental conditions.

By Brendan Borrell
24 April 2023 | 4 min read
Illustration of a room with DNA sequence wallpaper and three doors leading to abstract new environments.

The future of autism therapies: A conversation with Lilia Iakoucheva and Derek Hong

If a therapy for autism’s core traits makes it to market, it will likely take one of three forms, the researchers say.

By Peter Hess
14 April 2023 | 5 min read
MRI scan of a 2-year-old child.

Mapping genetic influences on the infant brain: A chat with Rebecca Knickmeyer

Researchers know little about the ways genetic variants affect development in the infant brain. Knickmeyer, who launched the Organization for Imaging Genomics in Infancy, has spent the past five years trying to close the gap.

By Laura Dattaro
27 February 2023 | 6 min read
A pattern in the style of genetic sequencing forms into the shape of the African continent.

Africa’s genomic role: Q&A with Conrad Iyegbe and Niran Okewole

Psychiatric genomics promises to shed light on the genetic basis of autism, but it’s vital to include Africa in this research, Iyegbe and Okewole say.

By Charles Q. Choi
28 November 2022 | 7 min read
Conceptual illustration of a door leading from one area of the brain to another area of the brain.

Autism’s genetic heterogeneity evident in brain connectivity patterns

The results highlight the importance of subgrouping study participants based on their underlying genetics, the researchers say.

By Angie Voyles Askham
27 September 2022 | 5 min read

Mutations disrupting chromatin interactions contribute to autism

The mutations occur spontaneously in noncoding stretches of DNA that control gene expression.

By Giorgia Guglielmi
8 August 2022 | 5 min read
A pregnant woman and another figure are obscured by shadows.

Maternal genetics may confound studies of autism’s link to prenatal factors

Women who carry genetic variants tied to autism have an elevated chance of experiencing pregnancy-related events linked to the condition in their children.

By Charles Q. Choi
2 August 2022 | 5 min read

Explore more from The Transmitter

Piggy bank with half of its body replaced by a brain.

Neuroscientists reeling from past cuts advocate for more BRAIN Initiative funding

The director of the U.S. National Institutes of Health calls BRAIN a “high priority” but acknowledges that difficult decisions lie ahead if federal budgets remain flat.

By Angie Voyles Askham
22 November 2024 | 5 min read
A repeating pattern of orange butterflies against a blue background.

‘Huge influx’ of neuroscientists migrates to Bluesky

Daily neuroscience-related posts on the social-media platform this week have increased more than 400 percent, on average, compared with October.

By Calli McMurray
21 November 2024 | 5 min read
Woman in a clinician's office.

Autism prevalence increasing in children, adults, according to electronic medical records

The uptick from 2011 to 2022 in the United States underscores a need for more services and research, the investigators say.

By Shaena Montanari
21 November 2024 | 2 min read