GWAS

Recent articles

Research image of gene expression.

Sequencing study spotlights tight web of genes tied to autism

The findings, shared in a preprint, help to illuminate how a large and heterogeneous group of genes could be involved in autism.

By Katie Moisse
13 March 2025 | 5 min read
A younger looking set of hands holds an older looking set of hands.

New catalog charts familial ties from autism to 90 other conditions

The research tool reveals associations stretching across three generations.

By Charles Q. Choi
17 October 2024 | 4 min read
Illustration of a brain made up of many smaller brains.

Breaking down the winner’s curse: Lessons from brain-wide association studies

We found an issue with a specific type of brain imaging study and tried to share it with the field. Then the backlash began.

By Nico Dosenbach, Scott Marek
25 March 2024 | 7 min listen

Common genetic variants shape the structure of the cortex

A genome-wide association study lays a foundation for deeper investigation of these variants in neurodevelopmental conditions.

By Lauren Schenkman
18 September 2023 | 6 min listen
Research diagram of gene clusters.

Atlas of gene activity in prenatal brain holds clues to autism

Genes exert their strongest influence on the brain in the first half of gestation — a key window for autism and other neurodevelopmental conditions.

By Brendan Borrell
24 April 2023 | 4 min read
Illustration of a room with DNA sequence wallpaper and three doors leading to abstract new environments.

The future of autism therapies: A conversation with Lilia Iakoucheva and Derek Hong

If a therapy for autism’s core traits makes it to market, it will likely take one of three forms, the researchers say.

By Peter Hess
14 April 2023 | 5 min read
MRI scan of a 2-year-old child.

Mapping genetic influences on the infant brain: A chat with Rebecca Knickmeyer

Researchers know little about the ways genetic variants affect development in the infant brain. Knickmeyer, who launched the Organization for Imaging Genomics in Infancy, has spent the past five years trying to close the gap.

By Laura Dattaro
27 February 2023 | 6 min read
A pattern in the style of genetic sequencing forms into the shape of the African continent.

Africa’s genomic role: Q&A with Conrad Iyegbe and Niran Okewole

Psychiatric genomics promises to shed light on the genetic basis of autism, but it’s vital to include Africa in this research, Iyegbe and Okewole say.

By Charles Q. Choi
28 November 2022 | 7 min read
Conceptual illustration of a door leading from one area of the brain to another area of the brain.

Autism’s genetic heterogeneity evident in brain connectivity patterns

The results highlight the importance of subgrouping study participants based on their underlying genetics, the researchers say.

By Angie Voyles Askham
27 September 2022 | 5 min read

Mutations disrupting chromatin interactions contribute to autism

The mutations occur spontaneously in noncoding stretches of DNA that control gene expression.

By Giorgia Guglielmi
8 August 2022 | 5 min read

Explore more from The Transmitter

NIH campus in Bethesda, Maryland.

Acting NIH director dismisses four neuroscientists from advisory boards

The letters they received this week did not include a reason for their termination.

By Calli McMurray, Angie Voyles Askham
25 March 2025 | 5 min read
Research image of protein synthesis in mice.

NIH neurodevelopmental assessment system now available as iPad app

Here is a roundup of autism-related news and research spotted around the web for the week of 24 March.

By Jill Adams
25 March 2025 | 2 min read
Illustration of a face covered by several black rectangles.

Keep sex as a biological variable: Don’t let NIH upheaval turn back the clock on scientific rigor

Even in the absence of any formal instruction to do so, we should continue to hold our ourselves and our neuroscience colleagues accountable for SABV practices.

By Rebecca Shansky
25 March 2025 | 7 min read