Gene networks

Recent articles

Research image of gene expression.

Sequencing study spotlights tight web of genes tied to autism

The findings, shared in a preprint, help to illuminate how a large and heterogeneous group of genes could be involved in autism.

By Katie Moisse
13 March 2025 | 5 min read
Research image of mouse brain slices.

Newfound gene network controls long-range connections between emotional, cognitive brain areas

The finding could help unravel gene regulatory networks and explain how genetic and environmental factors interact in neurodevelopmental conditions.

By Charles Q. Choi
14 November 2024 | 4 min read
Research image of fetal macaque brains.

Brain patterning in utero may be implicated in autism, other conditions

Genes tied to several conditions are expressed in regions that control neural stem cell fate within the first few months post-conception.

By Chloe Williams
1 August 2024 | 6 min read
A diagram of autism-linked genes.

Autism-linked proteins mingle with other molecules in overlapping networks

A massive new set of interaction maps illuminates especially high convergence in protein networks related to autism and shows how mutations could disrupt those networks.

By Alla Katsnelson
8 February 2024 | 5 min read
Illustration of half of a brain on the left and half of a heart on the right

Change of heart and mind: Autism’s ties to cardiac defects

Children with congenital heart disease have an increased likelihood of autism. Why?

By Lauren Schenkman
21 July 2023 | 12 min read

Fishing for protein partners nets clues to autism

Connections between 13 autism-linked proteins and their binding partners in excitatory neurons implicate a new molecular pathway.

By Holly Barker
6 February 2023 | 5 min read
lllustration of the junction between two nerve cells.

Multi-omics study captures CNTNAP2’s far-ranging effects

The in-depth approach shows mutations in the autism-linked gene disrupt neuronal growth and communication, as well as mitochondrial gene expression.

By Charles Q. Choi
8 December 2022 | 4 min read

Two top autism-linked proteins connect to build cell ‘skeleton’

ADNP and SHANK3 proteins may bind together and alter a neuron’s internal scaffold, hinting at a mechanism that, when disrupted, may underlie several forms of autism.

By Chloe Williams
9 June 2022 | 5 min read

Autism and the complete human genome: Q&A with Evan Eichler

Scientists have at last filled in the missing gaps — an advance likely to inform every aspect of autism genetics research, Eichler says.

By Charles Q. Choi
10 May 2022 | 8 min read
DNA helix inside the human body

Autism genetics, explained

The more scientists dig into DNA, the more intricate its contribution to autism seems to be. Here, we unravel the complex genetics of autism.

By Nicholette Zeliadt
28 May 2021 | 5 min read

Explore more from The Transmitter

NIH campus in Bethesda, Maryland.

Acting NIH director dismisses four neuroscientists from advisory boards

The letters they received this week did not include a reason for their termination.

By Calli McMurray, Angie Voyles Askham
25 March 2025 | 5 min read
Research image of protein synthesis in mice.

NIH neurodevelopmental assessment system now available as iPad app

Here is a roundup of autism-related news and research spotted around the web for the week of 24 March.

By Jill Adams
25 March 2025 | 2 min read
Illustration of a face covered by several black rectangles.

Keep sex as a biological variable: Don’t let NIH upheaval turn back the clock on scientific rigor

Even in the absence of any formal instruction to do so, we should continue to hold our ourselves and our neuroscience colleagues accountable for SABV practices.

By Rebecca Shansky
25 March 2025 | 7 min read