The future of fMRI

Recent articles

This series of essays explores new developments and challenges in human brain imaging.

A hand holds multi-colored cubes.

Should we use the computational or the network approach to analyze functional brain-imaging data—why not both?

Emerging methods make it possible to combine the two tactics from opposite ends of the analytic spectrum, enabling scientists to have their cake and eat it too.

By Mac Shine
13 May 2024 | 7 min listen
Illustration of a hand reaching out to adjust a dial that sits in the middle of several images depicting brain activity and various behaviors.

To improve big data, we need small-scale human imaging studies

By insisting that every brain-behavior association study include hundreds or even thousands of participants, we risk stifling innovation. Smaller studies are essential to test new scanning paradigms.

By Emily S. Finn
15 April 2024 | 7 min read
An illustration of a mouse sitting in an armchair next to a framed picture of mouse brains

To make fMRI more clinically useful, we need to really get BOLD

A better understanding of the blood oxygen level dependent, or BOLD, signal requires more support for multimodal imaging studies.

By Evelyn Lake
22 January 2024 | 6 min read

Get notified every time a new column in this series is published.

Explore more from The Transmitter

Image of squirrels on a branch.

NeuroAI and the hidden complexity of agency

As we attempt to build autonomous artificial-intelligence systems, we're discovering that a capability we take for granted in animals may be much more complex than we imagined.

By Anthony Zador
5 February 2025 | 6 min read

Plaque levels differ in popular Alzheimer’s mouse model depending on which parent’s variants are passed down

5XFAD model mice that inherit two disease-related genes from their fathers have double the plaques seen in those with maternal inheritance, a new study shows.

By Shaena Montanari
4 February 2025 | 0 min watch
The word Doctored spelled out on pills.

‘Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer’s,’ an excerpt

In his new book, published today, investigative journalist Charles Piller tells the story of the scientific misconduct that shook Alzheimer’s disease research to its core, and the neuroscientist who helped to expose it.

By Charles Piller
4 February 2025 | 9 min read