Female protective effect

Recent articles

Research image highlighting different brain regions.

X marks the spot in search for autism variants

Genetic variants on the X chromosome, including those in the gene DDX53, contribute to autism’s gender imbalance, two new studies suggest.

By Holly Barker
16 January 2025 | 6 min read
Illustration of children looking at a gigantic set of building blocks, some of which display genetic sequences on their surfaces.

Autism is more heritable in boys than in girls

If boys have greater inherited liability for autism, the female protective effect may not fully explain the sex difference in prevalence.

Research illustration groups genes by their effects on brain cell types.

Giant analysis reveals how autism-linked genes affect brain cell types

Genes that predispose people to autism account for a large portion of the neuronal and glial cell changes seen in those with the condition.

By Charles Q. Choi
20 June 2024 | 5 min read
Composite research image of organoids at several stages of development.

Genetic background sways effects of autism-linked mutation

Experiments offer clues to why certain mutations are associated with autism in some people and not others.

By Charles Q. Choi
18 May 2023 | 4 min read
Illustration of an X chromosome against a black background.

X-chromosome variants help explain autism’s sex bias

The rare variants are also linked to ADHD and Tourette syndrome, two other conditions that disproportionately affect boys and men.

By Charles Q. Choi
24 October 2022 | 4 min read

Explore more from The Transmitter

Illustration of an open journal featuring lines of text and small illustrations of eyes and mouths.

Interneurons’ role in epilepsy, and more

Here is a roundup of autism-related news and research spotted around the web for the week of 9 February.

By Jill Adams
10 February 2026 | 1 min read
Research image of neuronal proteins in mice.

Aging neurons outsource garbage disposal, clog microglia

Degradation-resistant proteins pass from neurons to glial cells in a process that may spread protein clumps around the brain, according to a study in mice.

By Holly Barker
10 February 2026 | 4 min read
Monkey against a soft, colorful background.

Oregon primate research center to negotiate with NIH on possible transition to sanctuary

The board of directors at Oregon Health & Science University, which runs the primate center, voted unanimously in favor of the move.

By Calli McMurray
9 February 2026 | 6 min read

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