Excitatory signaling
Recent articles
‘Understudied secret’ in brain dampens nicotine drive in mice
The interpeduncular nucleus produces an aversion to nicotine, even at low doses, and helps moderate how rewarding mice find the drug.
‘Understudied secret’ in brain dampens nicotine drive in mice
The interpeduncular nucleus produces an aversion to nicotine, even at low doses, and helps moderate how rewarding mice find the drug.
Inhibitory cells work in concert to orchestrate neuronal activity in mouse brain
A cubic millimeter of brain tissue, meticulously sectioned, stained and scrutinized over the past seven years, reveals in stunning detail the role of inhibitory interneurons in brain structure and function.
Inhibitory cells work in concert to orchestrate neuronal activity in mouse brain
A cubic millimeter of brain tissue, meticulously sectioned, stained and scrutinized over the past seven years, reveals in stunning detail the role of inhibitory interneurons in brain structure and function.
Bespoke photometry system captures variety of dopamine signals in mice
The tool tracks the excitation of an engineered protein that senses dopamine’s absolute levels, including fast and slow fluctuations in real time, and offers new insights into how the signals change across the brain.
Bespoke photometry system captures variety of dopamine signals in mice
The tool tracks the excitation of an engineered protein that senses dopamine’s absolute levels, including fast and slow fluctuations in real time, and offers new insights into how the signals change across the brain.
What are recurrent networks doing in the brain?
The cortex is filled with excitatory local synapses, but we know little about their role in brain function. New experimental tools, along with ideas from artificial intelligence, are poised to change that.
What are recurrent networks doing in the brain?
The cortex is filled with excitatory local synapses, but we know little about their role in brain function. New experimental tools, along with ideas from artificial intelligence, are poised to change that.
Newfound gene network controls long-range connections between emotional, cognitive brain areas
The finding could help unravel gene regulatory networks and explain how genetic and environmental factors interact in neurodevelopmental conditions.
Newfound gene network controls long-range connections between emotional, cognitive brain areas
The finding could help unravel gene regulatory networks and explain how genetic and environmental factors interact in neurodevelopmental conditions.
As circuits wire up, interneurons take cues from surrounding cells
The inhibitory cells’ development, diversity and abundance in the cortex is directed in part by pyramidal cells, a new preprint suggests.
As circuits wire up, interneurons take cues from surrounding cells
The inhibitory cells’ development, diversity and abundance in the cortex is directed in part by pyramidal cells, a new preprint suggests.
Brain patterning in utero may be implicated in autism, other conditions
Genes tied to several conditions are expressed in regions that control neural stem cell fate within the first few months post-conception.
Brain patterning in utero may be implicated in autism, other conditions
Genes tied to several conditions are expressed in regions that control neural stem cell fate within the first few months post-conception.
Brain ‘chimeroids’ reveal person-to-person differences rooted in genetics
These fusions created from multiple donors’ organoids may help scale up comparative brain research.
Brain ‘chimeroids’ reveal person-to-person differences rooted in genetics
These fusions created from multiple donors’ organoids may help scale up comparative brain research.
Synaptic anomalies in autistic people support imbalance hypothesis
Increased excitatory and decreased inhibitory synapses in the prefrontal cortex of autistic people suggest broader impacts on brain function and connectivity.
Synaptic anomalies in autistic people support imbalance hypothesis
Increased excitatory and decreased inhibitory synapses in the prefrontal cortex of autistic people suggest broader impacts on brain function and connectivity.
Opioid receptors may guide formation of gut nervous system in zebrafish
Fish lacking functional copies of the receptors have fewer enteric neurons than usual, but the findings await further validation.
Opioid receptors may guide formation of gut nervous system in zebrafish
Fish lacking functional copies of the receptors have fewer enteric neurons than usual, but the findings await further validation.
Explore more from The Transmitter
Xiao-Jing Wang outlines the future of theoretical neuroscience
Wang discusses why he decided the time was right for a new theoretical neuroscience textbook and how bifurcation is a key missing concept in neuroscience explanations.
Xiao-Jing Wang outlines the future of theoretical neuroscience
Wang discusses why he decided the time was right for a new theoretical neuroscience textbook and how bifurcation is a key missing concept in neuroscience explanations.
Memory study sparks debate over statistical methods
Critics of a 2024 Nature paper suggest the authors failed to address the risk of false-positive findings. The authors argue more rigorous methods can result in missed leads.
Memory study sparks debate over statistical methods
Critics of a 2024 Nature paper suggest the authors failed to address the risk of false-positive findings. The authors argue more rigorous methods can result in missed leads.
Attention not necessary for visual awareness, large study suggests
People can perceive some visual information even if they do not pay direct attention to it.
Attention not necessary for visual awareness, large study suggests
People can perceive some visual information even if they do not pay direct attention to it.