Excitatory signaling
Recent articles
Sensory gatekeeper drives seizures, autism-like behaviors in mouse model
The new work, in mice missing the autism-linked gene CNTNAP2, suggests a mechanism to help explain the overlap between epilepsy and autism.
Sensory gatekeeper drives seizures, autism-like behaviors in mouse model
The new work, in mice missing the autism-linked gene CNTNAP2, suggests a mechanism to help explain the overlap between epilepsy and autism.
‘Understudied secret’ in brain dampens nicotine drive in mice
The interpeduncular nucleus produces an aversion to nicotine, even at low doses, and helps moderate how rewarding mice find the drug.
‘Understudied secret’ in brain dampens nicotine drive in mice
The interpeduncular nucleus produces an aversion to nicotine, even at low doses, and helps moderate how rewarding mice find the drug.
Inhibitory cells work in concert to orchestrate neuronal activity in mouse brain
A cubic millimeter of brain tissue, meticulously sectioned, stained and scrutinized over the past seven years, reveals in stunning detail the role of inhibitory interneurons in brain structure and function.
Inhibitory cells work in concert to orchestrate neuronal activity in mouse brain
A cubic millimeter of brain tissue, meticulously sectioned, stained and scrutinized over the past seven years, reveals in stunning detail the role of inhibitory interneurons in brain structure and function.
Bespoke photometry system captures variety of dopamine signals in mice
The tool tracks the excitation of an engineered protein that senses dopamine’s absolute levels, including fast and slow fluctuations in real time, and offers new insights into how the signals change across the brain.
Bespoke photometry system captures variety of dopamine signals in mice
The tool tracks the excitation of an engineered protein that senses dopamine’s absolute levels, including fast and slow fluctuations in real time, and offers new insights into how the signals change across the brain.
What are recurrent networks doing in the brain?
The cortex is filled with excitatory local synapses, but we know little about their role in brain function. New experimental tools, along with ideas from artificial intelligence, are poised to change that.
What are recurrent networks doing in the brain?
The cortex is filled with excitatory local synapses, but we know little about their role in brain function. New experimental tools, along with ideas from artificial intelligence, are poised to change that.
Newfound gene network controls long-range connections between emotional, cognitive brain areas
The finding could help unravel gene regulatory networks and explain how genetic and environmental factors interact in neurodevelopmental conditions.
Newfound gene network controls long-range connections between emotional, cognitive brain areas
The finding could help unravel gene regulatory networks and explain how genetic and environmental factors interact in neurodevelopmental conditions.
As circuits wire up, interneurons take cues from surrounding cells
The inhibitory cells’ development, diversity and abundance in the cortex is directed in part by pyramidal cells, a new preprint suggests.
As circuits wire up, interneurons take cues from surrounding cells
The inhibitory cells’ development, diversity and abundance in the cortex is directed in part by pyramidal cells, a new preprint suggests.
Brain patterning in utero may be implicated in autism, other conditions
Genes tied to several conditions are expressed in regions that control neural stem cell fate within the first few months post-conception.
Brain patterning in utero may be implicated in autism, other conditions
Genes tied to several conditions are expressed in regions that control neural stem cell fate within the first few months post-conception.
Brain ‘chimeroids’ reveal person-to-person differences rooted in genetics
These fusions created from multiple donors’ organoids may help scale up comparative brain research.
Brain ‘chimeroids’ reveal person-to-person differences rooted in genetics
These fusions created from multiple donors’ organoids may help scale up comparative brain research.
Synaptic anomalies in autistic people support imbalance hypothesis
Increased excitatory and decreased inhibitory synapses in the prefrontal cortex of autistic people suggest broader impacts on brain function and connectivity.
Synaptic anomalies in autistic people support imbalance hypothesis
Increased excitatory and decreased inhibitory synapses in the prefrontal cortex of autistic people suggest broader impacts on brain function and connectivity.
Explore more from The Transmitter
Psychedelics muddy fMRI results: Q&A with Adam Bauer and Jonah Padawer-Curry
The drugs disrupt the link between vascular and neuronal activity, which complicates interpretations of fMRI data. Adopting a more holistic view of what constitutes brain activity may help, the researchers say.
Psychedelics muddy fMRI results: Q&A with Adam Bauer and Jonah Padawer-Curry
The drugs disrupt the link between vascular and neuronal activity, which complicates interpretations of fMRI data. Adopting a more holistic view of what constitutes brain activity may help, the researchers say.
First Pan-African neuroscience journal gets ready to launch
With lower-than-average article processing fees, and issues dedicated to topics important to the continent, the journal hopes to give African neuroscience research much-needed international visibility.
First Pan-African neuroscience journal gets ready to launch
With lower-than-average article processing fees, and issues dedicated to topics important to the continent, the journal hopes to give African neuroscience research much-needed international visibility.
New method identifies two-hit genetic variation in autism; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 27 October.
New method identifies two-hit genetic variation in autism; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 27 October.