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Recent articles

Autism research hits the road

Some scientists are thinking creatively about how to collect data in flexible environments and meet communities where they’re at.

By Giorgia Guglielmi
8 December 2023 | 0 min watch
Three researchers, one wearing movement-tracking devices, walk around a university campus.

‘Into the wild’: Moving studies of memory and learning out of the lab

People with electrodes embedded deep in their brain are collaborating with a growing posse of plucky researchers to uncover the mysteries of real-world recall.

By Katie Moisse
13 November 2023 | 10 min listen
Illustration of a sheet of red and white pills, with the red pills arranged in the form of a question mark.

Trials test utility of EEG biomarkers for autism-related conditions

This month’s Going on Trial newsletter dives into an electroencephalography biomarker that could track the efficacy of treatments for dup15q and Angelman syndromes, among other drug development news.

By Calli McMurray
31 August 2023 | 7 min read
Close up of blood vessels shows probe sticking to vessel wall.

Brain-surgery-free probes can record single-neuron activity

The new devices, which monitor neural activity from within blood vessels, show long-term stability in rats and could one day deliver electrical stimulation.

By Charles Q. Choi
15 August 2023 | 5 min read
Illustration of hybrid objects: part light bulb, part lab vial, some in blue and some in red to signify null and replicated results.

Prenatal exposures; Angelman trial suspension; autistic adult well-being

This month’s issue of the Null and Noteworthy newsletter breaks down some negative results involving prenatal exposures, an experimental treatment for Angelman syndrome, and the role that age at autism diagnosis plays in subsequent outcomes, and more.

By Emily Harris
17 July 2023 | 4 min read
Research image of brain activity during conversation.

AI model helps decode brain activity underlying conversation

A text-predicting chatbot parses text from conversations in a way that parallels brain-activity patterns associated with speech production and comprehension.

By Alla Katsnelson
15 June 2023 | 6 min listen
A young woman sleeps at home wearing a Dreem headband and surrounded by stuffed animals.

Capturing autism’s sleep problems with devices nearable and wearable

Next-generation trackers could realize a long-standing research dream: conducting sleep studies in large numbers of autistic people.

By Angie Voyles Askham, Peter Hess
6 June 2023 | 9 min read

Wearable device records, stimulates single neurons in people on the go

The tool connects to electrodes implanted in people with epilepsy or other brain conditions and can monitor and regulate neurons during everyday activities.

By Charles Q. Choi
17 March 2023 | 5 min read

Adult Angelman mice get some benefit from boosting UBE3A gene expression

The treatment eases the animals’ sleep troubles, suggesting it has clinically meaningful effects beyond what was thought to be a critical window in early life.

By Angie Voyles Askham
9 February 2023 | 5 min read
A transplanted human organoid labeled with a fluorescent protein in a section of the rat brain.

Human cortical organoids forge functional circuits in rat brains

The transplanted cells integrate into living animals’ neural circuitry and influence behavior.

By Peter Hess
12 October 2022 | 4 min read

Explore more from The Transmitter

What’s next for brain-directed gene therapy after death in Neurogene trial

The incident highlights that viral vectors can trigger deadly immune responses even when delivered directly to the nervous system.

By Calli McMurray
26 November 2024 | 6 min read
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Hessameddin Akhlaghpour outlines how RNA may implement universal computation

Could the brain’s computational abilities extend beyond neural networks to molecular mechanisms? Akhlaghpour describes how natural universal computation may have evolved via RNA mechanisms.

By Paul Middlebrooks
26 November 2024 | 107 min listen
Research image of the NMDA receptor in humans.

Emotional dysregulation; NMDA receptor variation; frank autism

Here is a roundup of autism-related news and research spotted around the web for the week of 25 November.

By Jill Adams
26 November 2024 | 1 min read