Drosophila

Recent articles

Multiple people look together at a whiteboard in a lab.

Why practical summer courses in neuroscience matter

Among other reasons, this tradition helps researchers rekindle the unfettered joy that initially brought them to the field.

By John Tuthill
13 January 2025 | 7 min read
Research image of neurons in the fly’s ventral nerve cord.

New connectomes fly beyond the brain

Researchers are mapping the neurons in Drosophila’s ventral nerve cord, where the central nervous system meets the rest of the body.

By Laura Dattaro
26 July 2024 | 7 min read
A dense reconstruction of layer 2/3 neurons of the mouse visual cortex containing 394 neurons and 3.2 million synapses.

To develop better nervous-system visualizations, we need to think BIG

With a full mouse connectome on the horizon, neuroscience needs to overcome its legacy of minimalism and embrace the contemporary challenge of representing whole-nervous-system connectivity.

By Tyler Sloan
8 July 2024 | 8 min read
Close-up image of a dead fly with visible growths protruding from its abdomen due to Entomophthora fungus infection.

Mind control in zombie flies: Q&A with Carolyn Elya

A parasitic fungus compels its insect host to behave in strange ways by hijacking secretory neurons and circadian pathways.

By Shaena Montanari
25 June 2024 | 5 min read
Photograph of Eugenia Chiappe jumping inside a glass hallway.

Decoding flies’ motor control with acrobat-scientist Eugenia Chiappe

The tiny performers steal the show in Chiappe’s sensorimotor-integration lab in Lisbon, Portugal.

By Elissa Welle
7 May 2024 | 6 min read
Composite of images of fruit flies taking flight.

Seen and heard: The Transmitter’s top multimedia stories in 2023

Our audio, video and photo highlights from the past year help to transport readers into scientists’ lives and research, and the lives of their study participants.

By The Transmitter
29 December 2023 | 3 min read
Still from research video displaying wiring map of a fruit fly's brain.

Standout neuroscience news in 2023

Did you miss any of our favorite stories from the past year? Revisit them here.

By The Transmitter
27 December 2023 | 4 min read

Reading fly minds in a mini-IMAX theater

The setup, involving a custom fly-releasing “PEZ dispenser,” makes it possible to map out — neuron by neuron — how individual insects respond to an imaginary predator.

By Angie Voyles Askham, Rebecca Horne
13 November 2023 | 5 min watch
Research image of presynapses on sensory neurons in fruit flies.

UBE3A’s link to synaptic pruning bolstered by fly study

Increasing or reducing the levels of the UBE3A gene, which is associated with autism and autism-related syndromes, results in altered patterns of synaptic pruning — a process that snips away brain cell connections.

By Giorgia Guglielmi
28 September 2023 | 5 min read

Full connectome of adult fruit fly completed, with help from citizen scientists

The map, by far the largest one of an entire brain to date, contains 130,000 neurons and 53 million synapses.

By Laura Dattaro
7 August 2023 | 6 min read

Explore more from The Transmitter

Pixelated human brain scans showing the distribution of mitochondria.

Mitochondrial ‘landscape’ shifts across human brain

Evolutionarily newer regions sport mitochondria with a higher capacity for energy production than older regions, according to the first detailed map of the organelles in a tissue slice, adding to mounting evidence that the brain features a metabolic gradient.

By Claudia López Lloreda
25 April 2025 | 6 min read
A clinician holds a clipboard while someone else sits on a couch.

Expediting clinical trials for profound autism: Q&A with Matthew State

Aligning Research to Impact Autism, a new initiative funded by the Sergey Brin Family Foundation, wants to bring basic science discoveries to the clinic faster.

By Lauren Schenkman
24 April 2025 | 8 min read
Illustration of astrocytes in a petri dish.

This paper changed my life: Shane Liddelow on two papers that upended astrocyte research

A game-changing cell culture method developed in Ben Barres’ lab completely transformed the way we study astrocytes and helped me build a career studying their reactive substates.

By Shane Liddelow
23 April 2025 | 6 min read