Developmental neuroscience

Recent articles

Illustration of cells converting from fibroblasts to myoblasts.

This paper changed my life: Learning the molecular rules of cell identity

A 1987 Cell paper showed that a single transcription factor could turn fibroblasts into muscle cells. The work inspired Ardem Patapoutian to think about the molecular codes that define neuronal subtypes.

By Ardem Patapoutian
17 June 2026 | 6 min read
Research image of zebrafish brain activity.

Nearly 400 compounds affect behaviors tied to autism-linked genes in zebrafish

Estropipate, paclitaxel and levocarnitine altered behaviors tied to SCN2A and DYRK1A variants specifically, a new open-source platform revealed.

By Charles Q. Choi
16 April 2026 | 4 min read
Research image of brain activity in infants.

Infant visual system categorizes common objects by 2 months of age

Brain activity patterns in the ventral visual cortex appear to distinguish images across 12 categories, including birds and trees, longitudinal functional MRI scans suggest.

By Helena Kudiabor
24 February 2026 | 5 min read
Research image of the mouse dentate gyrus.

Microglia implicated in infantile amnesia

The glial cells could explain the link between maternal immune activation and autism-like behaviors in mice.

By Lauren Schneider
12 February 2026 | 5 min read
Research image of myelinated axons.

Oligodendrocytes need mechanical cues to myelinate axons correctly

Without the mechanosensor TMEM63A, the cells cannot deposit the appropriate amount of insulation, according to a new study.

By Calli McMurray
11 February 2026 | 5 min read
Research image of the mouse dorsal horn.

Cell atlas cracks open ‘black box’ of mammalian spinal cord development

The atlas details the genetics, birth dates and gene-expression signatures of roughly 150 neuron subtypes in the dorsal horn of the mouse spinal cord.

By Natalia Mesa
3 February 2026 | 5 min read
Marmoset brain slices.

Prenatal viral injections prime primate brain for study

The approach makes it possible to deploy tools such as CRISPR and optogenetics across the monkey brain before birth.

By Angie Voyles Askham
22 January 2026 | 5 min read
Research image of stem cells derived from people of African ancestry.

Bringing African ancestry into cellular neuroscience

Two independent teams in Africa are developing stem cell lines and organoids from local populations to explore neurodevelopmental and neurodegenerative conditions.

By Lauren Schenkman
14 January 2026 | 7 min read

Waves of calcium activity dictate eye structure in flies

Synchronized signals in non-neuronal retinal cells draw the tiny compartments of a fruit fly’s compound eye into alignment during pupal development.

By Lauren Schneider
12 December 2025 | 0 min watch
Research image of microglia in organoids.

Microglia nurture young interneurons

The immune cells secrete a growth factor that “sets the supply of GABAergic interneurons in the developing brain.”

By Lauren Schenkman
28 August 2025 | 3 min read

Explore more from The Transmitter

Connexiohuman Connexin 26 dodecamer at 90mmHg PCO2, pH7.4

Designer synapses edit brain circuits in living animals

The approach could help elucidate relationships between circuit structure and function, as well as the role of natural electrical synapses.

By Simon Makin
23 June 2026 | 5 min read
Research image of cortical excitation–inhibition balance.

Role of GABA-A receptors in dup15q syndrome, and more

Here is a roundup of autism-related news and research spotted around the web for the week of 22 June.

By Jill Adams
23 June 2026 | 2 min read
Thermal image of Danionella fish.

Exclusive: Janelia sunsets rodent work, launches transparent fish project

The Howard Hughes Medical Institute’s Janelia Research Campus is banking on whole-brain imaging in the Danionella fish to advance neuroscience, but some scientists forced to close their labs say that even with a three-year runway and transitional support, they feel betrayed by the pivot.

By Calli McMurray
22 June 2026 | 5 min read