Developmental neuroscience
Recent articles
How thirteen-lined ground squirrels illuminate retinal development
In most mammalian retinas, rods outnumber cones. But that ratio is flipped in ground squirrels, a quirk that helps Seth Blackshaw explore how retinal cells develop their identities.
How thirteen-lined ground squirrels illuminate retinal development
In most mammalian retinas, rods outnumber cones. But that ratio is flipped in ground squirrels, a quirk that helps Seth Blackshaw explore how retinal cells develop their identities.
Neurons engage in risky, DNA-breaking business during migration
The cells later repair the damage, which occurs mostly in transcriptionally silent parts of the genome.
Neurons engage in risky, DNA-breaking business during migration
The cells later repair the damage, which occurs mostly in transcriptionally silent parts of the genome.
This paper changed my life: Learning the molecular rules of cell identity
A 1987 Cell paper showed that a single transcription factor could turn fibroblasts into muscle cells. The work inspired Ardem Patapoutian to think about the molecular codes that define neuronal subtypes.
This paper changed my life: Learning the molecular rules of cell identity
A 1987 Cell paper showed that a single transcription factor could turn fibroblasts into muscle cells. The work inspired Ardem Patapoutian to think about the molecular codes that define neuronal subtypes.
Nearly 400 compounds affect behaviors tied to autism-linked genes in zebrafish
Estropipate, paclitaxel and levocarnitine altered behaviors tied to SCN2A and DYRK1A variants specifically, a new open-source platform revealed.
Nearly 400 compounds affect behaviors tied to autism-linked genes in zebrafish
Estropipate, paclitaxel and levocarnitine altered behaviors tied to SCN2A and DYRK1A variants specifically, a new open-source platform revealed.
Infant visual system categorizes common objects by 2 months of age
Brain activity patterns in the ventral visual cortex appear to distinguish images across 12 categories, including birds and trees, longitudinal functional MRI scans suggest.
Infant visual system categorizes common objects by 2 months of age
Brain activity patterns in the ventral visual cortex appear to distinguish images across 12 categories, including birds and trees, longitudinal functional MRI scans suggest.
Microglia implicated in infantile amnesia
The glial cells could explain the link between maternal immune activation and autism-like behaviors in mice.
Microglia implicated in infantile amnesia
The glial cells could explain the link between maternal immune activation and autism-like behaviors in mice.
Oligodendrocytes need mechanical cues to myelinate axons correctly
Without the mechanosensor TMEM63A, the cells cannot deposit the appropriate amount of insulation, according to a new study.
Oligodendrocytes need mechanical cues to myelinate axons correctly
Without the mechanosensor TMEM63A, the cells cannot deposit the appropriate amount of insulation, according to a new study.
Cell atlas cracks open ‘black box’ of mammalian spinal cord development
The atlas details the genetics, birth dates and gene-expression signatures of roughly 150 neuron subtypes in the dorsal horn of the mouse spinal cord.
Cell atlas cracks open ‘black box’ of mammalian spinal cord development
The atlas details the genetics, birth dates and gene-expression signatures of roughly 150 neuron subtypes in the dorsal horn of the mouse spinal cord.
Prenatal viral injections prime primate brain for study
The approach makes it possible to deploy tools such as CRISPR and optogenetics across the monkey brain before birth.
Prenatal viral injections prime primate brain for study
The approach makes it possible to deploy tools such as CRISPR and optogenetics across the monkey brain before birth.
Bringing African ancestry into cellular neuroscience
Two independent teams in Africa are developing stem cell lines and organoids from local populations to explore neurodevelopmental and neurodegenerative conditions.
Bringing African ancestry into cellular neuroscience
Two independent teams in Africa are developing stem cell lines and organoids from local populations to explore neurodevelopmental and neurodegenerative conditions.
Explore more from The Transmitter
Alison Barth discovers how different neuron types contribute to cortical function
Barth uses learning tasks in mice as a tool to drive synaptic plasticity in the sensory cortex, hoping to unlock more general principles of how the cortex works.
Alison Barth discovers how different neuron types contribute to cortical function
Barth uses learning tasks in mice as a tool to drive synaptic plasticity in the sensory cortex, hoping to unlock more general principles of how the cortex works.
Virus-like particles deliver gene-editing tools into Duchenne mouse model
The approach uses a protein found in fruit flies to ferry the gene editor Cas9 into muscle cells.
Virus-like particles deliver gene-editing tools into Duchenne mouse model
The approach uses a protein found in fruit flies to ferry the gene editor Cas9 into muscle cells.
Textbook model of hippocampus’s role in memory may need updating
The CA3 region, long thought to have just one circuit, has two, sporting different wiring and functions, a new preprint suggests.
Textbook model of hippocampus’s role in memory may need updating
The CA3 region, long thought to have just one circuit, has two, sporting different wiring and functions, a new preprint suggests.